PCO

Question 1

Classifications of WHO group of ovulation disorders

Answer 1

hypothalamic!pituitary!failure!(hypothalamic!amenorrhoea!or!hypogonadotrophic!hypogonadism).!• !They!can!improve!their!chance!of!regular!ovulation,!conception!and!an!uncomplicated!pregnancy!by:!• increasing!their!body!weight!if!they!have!a!BMI!of!less!than!19!.#;E5,/• moderating!their!exercise!levels!if!they!undertake!high!levels!of!exercise.!• Offer!women!with!WHO!Group!I!ovulation!disorders!pulsatile!administration!of!gonadotrophinreleasing!• hormone!or!gonadotrophins!with!luteinising!hormone!activity!to!induce!ovulation!ABC/?,5:)/DD/5’:-.&%5#/;%$5,;”,$!• hypothalamic-pituitaryovarian!dysfunction!(predominately!polycystic!ovary!syndrome).!• Advise!women!with!WHO!Group!II!anovulatory!infertility!who!have!a!BMI!of!30!or!over!to!lose!weight!!• !this!alone!may!restore!ovulation,!improve!their!response!to!ovulation!induction!agents,!and!have!a!positive!impact!on!pregnancy!outcomes!• WHO!group!3!is!ovarian!failure!

Question 2

PCOS

Answer 2

Hairsitisum can be sign of PCOS
Regular sex is better than ovulation kit
Reason of miscarriage could be sporadic and due to high BMI, faulty chromosomes
Folic acid 5 mg
Need to Do weight loss 5-10%
Increase chance of spontaneous pregnancy and better response to medication such as ovulation induction

Answer 3

Clinical signs of hyper androgenise
12 follicular more than 10 cubic centimetres
Oligo or an ovulation

Question 4

Significant of AMH

Answer 4

AMH: more than 35
debate whether or not

Question 5

Prevelance of PCOS

Answer 5

10-18%
Clomiphene resistance if not able to ovulate
Failure if not able to get pregnant despite ovulation