PCAP CPG Flashcards

1
Q

What are the clinical signs and symptoms that accurately diagnose community-acquired pneumonia in infants and children aged 3 months to 18 years?

A

Cough or fever, PLUS any of the following positive predictors:
* Tachypnea
* Retractions or chest indrawing
* Nasal flaring
* O2 saturation <95% at room air
* Grunting

Tachypnea thresholds vary by age group.

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2
Q

What is the tachypnea threshold for infants aged 3 to 12 months?

A

≥50 breaths per minute

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3
Q

What is the tachypnea threshold for children aged 1 to 5 years?

A

≥40 breaths per minute

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4
Q

What is the tachypnea threshold for children aged 5 to 12 years?

A

≥30 breaths per minute

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5
Q

What is the tachypnea threshold for children aged over 12 years?

A

≥20 breaths per minute

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6
Q

What clinical and ancillary parameters determine the need for admission in infants and children with community-acquired pneumonia?

A

Clinical parameters include:
* Respiratory signs
* Central Nervous System signs
* Circulatory signs
* General considerations
* Ancillary parameters

Different parameters are assessed based on severity.

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7
Q

In the 2021 PCAP CPG, what is the respiratory sign threshold for severe pneumonia in children aged 3 to 12 months?

A

> 60/min to ≤70/min

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8
Q

What is the general consideration for malnutrition in non-severe pneumonia according to 2021 PCAP CPG?

A

None or mild

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9
Q

What ancillary parameter is used to assess oxygen saturation in children with pneumonia?

A

Oxygen saturation at room air using pulse oximetry for 20-30 minutes

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10
Q

What is the recommended oxygen saturation threshold for admission in the 2021 PCAP CPG?

A

≥94%

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11
Q

What diagnostic aid is strongly recommended for severe community-acquired pneumonia in a hospital setting?

A

Chest X-ray

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12
Q

What is the role of procalcitonin (PCT) in diagnosing bacterial pneumonia?

A

Recommended to be used in conjunction with other factors such as clinical presentation and imaging modalities

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13
Q

True or False: Routine diagnostic aids are considered for non-severe pneumonia in an ambulatory setting.

A

False

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14
Q

What are the parameters suggestive of bacterial etiology for antibiotic treatment in pneumonia?

A
  • Elevated white blood cell count (WBC)
  • Elevated C-reactive protein (CRP)
  • Elevated procalcitonin (PCT)
  • Imaging findings such as alveolar infiltrates or unilateral consolidation

These parameters apply to both non-severe and severe pneumonia.

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15
Q

What is the recommended empiric treatment for non-severe pneumonia?

A

Options include:
* Amoxicillin trihydrate
* Amoxicillin-clavulanate
* Cefuroxime

Dosing varies based on age and severity.

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16
Q

What is the recommended empiric treatment for severe pneumonia?

A

Options include:
* Penicillin G
* Ampicillin
* Cefuroxime
* Ceftriaxone
* Ampicillin-sulbactam
* Clindamycin
* Vancomycin for severe cases

Dosing and selection depend on vaccination status and local resistance data.

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17
Q

What is the significance of chest X-ray findings in severe pneumonia?

A

Findings of effusion, abscess, air leak, or multilobar consolidation indicate severe pneumonia.

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18
Q

What clinical signs indicate the need for admission in severe pneumonia?

A

Signs include:
* Cyanosis/Hypoxemia
* Altered sensorium
* Poor perfusion
* Severe malnutrition

These signs help assess the severity and need for intervention.

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19
Q

Fill in the blank: Empiric antibiotic therapy is considered to be started in patients with clinical signs and symptoms of pneumonia with _______ suggestive of bacterial etiology.

A

[ANY parameters]

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20
Q

What is the preferred dosage of Vancomycin?

A

40-60 mg/kg/day Q6 to Q8

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21
Q

What empiric treatment is effective for infants and children aged 3 months to 18 years with community-acquired pneumonia if a bacterial etiology is considered?

A

Cefuroxime or Ceftriaxone

22
Q

What is the dosage for Cefuroxime in patients with non-type 1 hypersensitivity to Penicillin?

A

PO 20-30mg/kg/day Q12 or IV 100-150mg/kg/day Q8

23
Q

What is the recommended treatment for patients with type 1 hypersensitivity to Penicillin?

A

Azithromycin, Clarithromycin, or Clindamycin

24
Q

What is the dosage for Azithromycin in patients with type 1 hypersensitivity?

A

10mg/kg/day PO or IV Q24 for 3 days or 10mg/kg/day on day 1 followed by 5 mg/kg/day Q24 for days 2 to 5

25
When an atypical pathogen is suspected in pneumonia, what is the treatment consideration?
Starting a macrolide
26
What is the recommended duration of treatment for uncomplicated bacterial pneumonia?
7 to 10 days
27
Is the addition of a macrolide to standard beta-lactam antibiotic therapy considered in the empiric treatment of bacterial pneumonia?
No
28
What is the recommended treatment if a viral etiology is considered for pneumonia?
Oseltamivir
29
What parameters indicate a good response to therapeutic management in non-severe pneumonia?
Clinical stability, improvement of cough, normalization of temperature
30
What parameters indicate a good response to therapeutic management in severe pneumonia?
Absence of danger signs, tachypnea, fever, tachycardia, improving radiologic findings
31
What diagnostic evaluations are considered for non-severe pneumonia patients not improving?
Coexisting agents, resistant etiologic agent, pneumonia-related complications
32
What is the recommended action for non-severe pneumonia patients not improving within 24-72 hours?
Increase antibiotic dosage or shift to a different antibiotic
33
What is the role of macrolides if an atypical pathogen is suspected in non-severe pneumonia?
Add Azithromycin or Clarithromycin
34
What diagnostic evaluations are considered for severe pneumonia patients not improving?
Cultures, imaging, biomarkers
35
What clinical parameters indicate that switch therapy can be considered in the management of severe pneumonia?
Parenteral antibiotic for at least 24 hours, afebrile for 8 hours, clinical improvement
36
What adjunctive treatment is strongly recommended for measles pneumonia?
Vitamin A
37
What treatments are not considered effective adjuncts for severe pneumonia?
Zinc, Vitamin D, mucokinetic agents
38
What strategies are recommended to prevent community-acquired pneumonia in children?
Vaccination, breastfeeding, avoiding smoke exposure
39
What is the impact of vaccination on pneumonia incidence in children?
Decreases incidence by up to 32%
40
What is the association between breastfeeding and pneumonia mortality?
Shorter duration of breastfeeding increases pneumonia mortality
41
What are the key vaccinations recommended to prevent pneumonia?
* Streptococcus pneumoniae * Haemophilus influenzae type b (Hib) * Bordetella pertussis * Rubeola virus * Influenza virus
42
What is whooping cough also known as?
Whooping cough ## Footnote WHO 2015
43
What is the impact of including PCVs in childhood immunization programs?
Inclusion reduces incidence of pneumonia in young children by up to 32% ## Footnote WHO 2015
44
What is the relationship between breastfeeding duration and pneumonia mortality?
Shorter breastfeeding duration is associated with pneumonia mortality ## Footnote Particularly among infants < 5 months of age
45
What is the increased risk factor for childhood lower respiratory tract infections (LRTI)?
Smoking by either parent ## Footnote Found in several studies
46
How does household air pollution affect childhood pneumonia risk?
Almost doubles the risk ## Footnote Responsible for 45% of pneumonia deaths in children < 5 years old (WHO, 2021)
47
What effect does daily zinc supplementation have on pneumonia prevention?
Can prevent pneumonia in children aged 2 to 59 months ## Footnote Daily supplementation of 10mg for at least 4 to 6 months
48
What immune response is enhanced by zinc supplementation in children?
Improves levels of complement in the blood and enhances T-lymphocytes, macrophages, and neutrophils ## Footnote Increases ability to fight infection (Lassi, 2016)
49
True or False: Exposure to indoor biomass fuel increases the risk of childhood pneumonia.
True ## Footnote Related to environmental tobacco smoke exposure
50
Fill in the blank: Exposure to household air pollution is responsible for _______ of all pneumonia deaths in children less than 5 years old.
45% ## Footnote WHO, Household Air Pollution and Health, 2021