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Midterm 4 > Pato Lab Soruları > Flashcards

Pato Lab Soruları Flashcards

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1
Q

Peripheral neuropathy in DM shows…

Endoneural arteriolar thickening
BM reduplication
Hyalinization and PAS + material accumulation in the wall
All

A

All

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2
Q

Neurons floating in the mixoid ground is a feature of…

Central neurocytoma
Ganglioglioma
Dysembryoplastic neuroepithelial tumor

A

Dysembryoplastic neuroepithelial tumor

Also, all of these tumors are neural tumors of CNS

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3
Q

Which of the following demyelinating disease is caused by viral infection of polioma virus?

ADEM (Acute disseminated encephalomyelitis)
SSPE (subacute sclerosing panencephalitis)
Acute hemorrhagic leukoencephalitis
Progressive multifocal leukoencephalopathy

A

Progressive multifocal leukoencephalopathy

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4
Q

Acute hypertensive encephalopathy is characterized by diffuse cerebral dysfunction with no spontanous recovery

Is this statement true or false?

A

True

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5
Q

There is no in situ/ premalignant / precursor lesions for CNS tumors

Is this statement true or false?

A

True

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6
Q

The autoimmune disease associated with acetylcholine receptors that make you stumble and fall?

Myasthenia gravis
Lambert- eaton myasthenic syndrome

A

…

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7
Q

The autoimmune disease associated with voltage gated calcium channel autoantibodies

Myasthenia gravis
Lambert- eaton myasthenic syndrome

A

Lambert- eaton myasthenic syndrome

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8
Q

Almost all cerebral infarction occurs with local vascular occlusion.

Is this statement true or false?

A

True

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9
Q

Which of the following is an anemic hypoxia reason that causes oxygen deprivation in the brain?

Cardiac arrest
Cyanide poisoning
Hypotension
CO poisoning

A

CO poisoning

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10
Q

Which of the following is a latent virus infection and presented with painful vesicular skin eruptions in dermatomes?

Leprosy neuropathy
Diphteric neuropathy
Varicella zoster neuropathy

A

Varicella zoster neuropathy

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11
Q

Central neurocytoma is a ventricular system located tumor with round uniform nuclei and neutrophil islands

Is this statement true or false?

A

True

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12
Q

The hyperacute reaction that shows the perivascular distribution of ADEM and sometimes kills within 48 hours?

SSPE (subacute sclerosing panencephalitis)
Acute hemorrhagic leukoencephalitis
Progressive multifocal leukoencephalopathy
Neuromyelitis optica (Devic’s disease)

A

Acute hemorrhagic leukoencephalitis

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13
Q

Which of the following is among vascular malformations of the CNS?

Arteriovenous malformation (AVM)
Capillary telangiestica
Cavernous hemangioma
All

A

All

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14
Q

Which of the following menengioma is considered as grade 3 tumor?

Fibrous
Clear cell
Papillary
Transitional

A

Papillary

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15
Q

Which of the following is observed in Pick disease?

Senile / neuritic plaques
Hirano bodies
Amyloid angiopathy
Swelling of the neurons

A

Swelling of the neurons

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16
Q

In ischemic encephalopathy, subacute changes are observed in 24 hours- 2 weeks and repair after 2 weeks.

Is this statement true or false?

A

True

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17
Q

The disease which is previously called perivenous, postinfectious or post vaccine encephalomyelitis?

ADEM (Acute disseminated encephalomyelitis)
SSPE (subacute sclerosing panencephalitis)
Acute hemorrhagic leukoencephalitis
Progressive multifocal leukoencephalopathy

A

ADEM (Acute disseminated encephalomyelitis)

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18
Q

ALS occurs after the 5th decade, is common in men and presented with asymmetrical weakness and respiratory failure

True/ false

A

True

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19
Q

Hypertensive intracerebral hemorrhage is mostly not in the basal ganglia.

True/ false

A

False. It is in the basal ganglia

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20
Q

Which of the following menengioma is considered as grade 2 tumor?

Meningothelial
Angiomatous
Choroid
Metaplastic

A

Choroid

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21
Q

Neurofibrillary tangles consists of double helix fibrils in the cytoplasm and presented as elonge shaped or flame shaped

True or False

A

True

22
Q

The muscular dystrophy with dangerous cardiac conduction defects and cardiomyopathy but not pseudohypertrophy

Becker muscular dystrophy
Duchenne muscular dystrophy
Emery dreifuss muscular dystrophy

A

Emery dreifuss muscular dystrophy

23
Q

Which cells are most susceptible to ischemia

Hippocampus pyramidal cells
Cerebral cortex cells
Cerebellar purkinje cells
All

A

All

24
Q

Pontocerebellar corner tumor is the tumor of … cranial nerve

8
9
10
11

A

8

25
Q

Segmental demyelination is the analogue of demyleination in the brain, axon is protected, myelin is lost

True/ false

A

True

26
Q

Anaplastic astrocytoma + atypical mitotic figures + palisading necrosis and VEP=?

Diffuse astrocytoma
Pilocytic astrocytoma
Glioblastoma

A

Glioblastoma

27
Q

Arterial hypertension is the most common cause of intrapenchymal hemorrhage?

True/ false

A

True

28
Q

IDH mutation frequency decreases as the grade of the tumor increases

True/ false

A

True

29
Q

Cortical symmetrical atrophy, most often in the frontal, temporal and parietal lobes is seen in Alzheimer’s disease

True/ false

A

True

30
Q

Median nerve compression by the transfer carpal ligament at the level of the wrist is named as carpal tunnel syndrome

True/ false

A

True

31
Q

Hypoxia- ischemia, infarction, intracranial hemorrhage and hypertensive cerebrovascular disease are 3 main CVD categories

True False

A

True

32
Q

In axonal degeneration, degeneration starts from the periphery of the axon and progress towards cell body/ dying back

True/ false

A

True

33
Q

A tumor which originates from the lining of the ventricular system…

Astrocytoma
Meningioma
Ependymoma

A

Ependymoma

34
Q

Demyleniating plaques have a tendency for optic chiasma and tract

True/ false

A

True

35
Q

Which astrocyoma has few mitosis no necrosis and no VEP?

Diffuse astrocytoma
Anaplastic astrocycoma
Glioblastoma

A

Anaplastic astrocycoma

36
Q

Which of the following is a degenerative disease of motor neurons?

Progressive supranuclear palsy
Amyotropic lateral sclerosis
Straintonigral degeneration
Shy drager syndrome

A

Amyotropic lateral sclerosis

37
Q

Muscular dystrophies are acquired myopathies with progressive muscle weakness and muscle fiber degeneration

True false

A

false.

Genetic, (AR) not acquired

38
Q

A small round cell tumor of childhood with homer wrigt rosettes, myc gene amplification and poor prognosis

Central neurocytoma
Meningioma
Medulloblastoma
Pilocytic astrocytoma

A

Medulloblastoma

39
Q

Wallerian degeneration develops after the cross section of the axon

True false

A

True

40
Q

Chemosensitive CNS tumor with soft, gelationous morphology and has prominent calcification?

Diffuse astrocytoma
Pilocytic astrocytoma
Oligodendroglioma
Meningioma

A

Oligodendroglioma

41
Q

CNS tumors usually spread outside of the CNS but they dont cause local infiltraton

True false

A

False

(neden false yaz)

42
Q

Pigment loss in substantia nigra and locus cereleus is observed in Parkinson’s disease

True false

A

True

43
Q

Which of the following tumors are among the intradural intraaxial located tumors?

Meningiomas
Neuroepithelial tumors
Nerve sheath tumors
All

A

Neuroepithelial tumors

44
Q

Triton tumor is a benign peripheral nerve sheath tumor with heterologous elements

True false

A

False.

It is heterologous but not benign, malignant.

45
Q

In ischemia, mild cases may show temporary confusion and then deep coma is observed in survivors

True false

A

False

(neden??)

46
Q

Dysembryoplastic neuroetpithelial tumor and ganglioglioma are low grade tumors with slow growth and present with seizures

True false

A

True

47
Q

A slowly progressive CNS infection that occurs years after measles infection which is decreased after routine vaccination.

ADEM (Acute disseminated encephalomyelitis)
SSPE (subacute sclerosing panencephalitis)
Acute hemorrhagic leukoencephalitis
Progressive multifocal leukoencephalopathy

A

SSPE (subacute sclerosing panencephalitis)

48
Q

Clinical manifestations of Parkinson’s disease includes…

Flexibility
Abnormal posture
Ä°ncrease in voluntary movements, decrease in involuntary movements
All

A

Abnormal posture

49
Q

Lambert- eaton myasthenic syndrome can be a paraneoplastic manifestation of…

Squamous cc of the lung
Small cc of the lung
Adenocarcinoma of the lung

A

Small cc of the lung

50
Q

Wernicke Korsakoff syndrome is a cause of secondary dementia

True / false

A

True.

Thiamine (B1) deficiency

51
Q

In neurofibromatosis, mutliple neurofibromas are observed

True / false

A

True

Midterm 4 (9 decks)

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