Patient Safety / Quality Assurance (26.5%) Flashcards

1
Q

What are High Alert Medications?

A

Drugs with heighten risk of causing significant patient harm when they used in error

  • Errors w/these drugs may or may not be more common that w/other drugs
  • However conseq. of errors can be SEVERE
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

High Alert Medications: Potential Safeguards

A
  • MANDATORY Patient Counseling
  • Standardized protocols
  • Education regarding their safety and use
  • Safeguards to limit access
  • Appropriate labeling
  • Use of IT tools
  • Manual double-checks when feasible
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Examples of High Alert Medications in Institutions (look at page 126 in PTCE book)

A
  • IV drugs used for cardiovascular
  • IV sedatives or anesthetic agents; inhaled volatile gases
  • IV antiarrhythmic drugs
  • Antithrombotic drugs: Reduce formation of blood clots
  • Chemotherapeutic agents
  • Hypertonic solutions
  • Epidural and intrathecal preps (pain relief – anathesia, spine work, etc.)
  • Insulin
  • Sterile water bags or vials GREATER than 100ml
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Examples of High Alert Medications in the Community

A
  • Anticoagulants are classified as high-alert medications because they cause fatal bleeding.
  • Neuromuscular blockers are classified as high-alert medications because they cause cessation of breathing.
  • Opioids are classified as high-alert medications because they cause fatal respiratory suppression.
  • Antiretroviral drugs
  • Chemotherapeutic drugs
  • Oral drugs that can cause hypoglycemia (blood glucose lower than normal)
  • Immune suppressing agents
  • Insulin
  • Opiods
  • Pediatric liquid medication
  • Drugs contraindicated in pregnancy (a particular technique or drug should not be used in the case in question).
  • Warfarin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Look-Alike Sound-Alike Medications (who publishes?)

A

• Institute for Safe Medication Practices (ISMP) publishes list of look-alike sound-alike (LASA) medications
o These meds are at risk for being confuse w/other meds
o Have tall man recommend lettering

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How can differentiate drugs? (LASA)

A
  • Require specific strats to differentiate drug from similar sounding and appearing drugs to reduce risk of errors.
  1. Use both brand and generic names on prescriptions and labels
  2. Include ID for drug on prescription
  3. Configure electronic health records and pharma info systems so that similar appear names not consecutive
  4. Use of tall man letter to draw attention to diffs in drug names, with TALL MAN lettering for different parts of names
    * e.g. NovoLOG vs. NovoLIN
    * DiazePAM vs DilTIAZem
    * RaNITIdine vs riMANTAdine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is a Medication Error?

A
  • Any PREVENTABLE event that may cause or lead to inappropriate medication use or patient harm while the med is in control of health care professional, patient or consumer.
  • Such events may be relate to profess practice, health care products, procedures, and systems, including prescribing, order commun, product labelling, packaging, nomenclature, compounding, dispensing, distribution, admin, education, monitoring and use.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Types of Adverse drug event (ADE)?

A

Adverse drug event (ADE): injury resulting from medical intervention related to drug

1) Preventable adverse drug event: An ADE that results from medication error that reaches patient and causes any degree of harm
2) Potential adverse drug event: Medication errors that do not do harm (either by chance or bs they were ID before reach patient)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the Medication Process?

A

1) Order/Prescribing: Prescriber must select the appropriate drug, at approp dose, frequency and duration
2) Transcribing: Written orders must be read, interpret and enter correctly. Verbal orders must be heard, interpret and enter correctly.
3) Preparation/Compound & Dispense: Includes pharmacist review of order for appropriateness, and provide correct drug formulation, quantity and instructs for use.
4) Administration: May be done by patient, caregiver, or healthcare provider.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the 5 Rights of Medication Administration?

A
  • Right Drug
  • Right Dose
  • Right Patient
  • Right Route
  • Right Time
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are typical Ordering and prescribing errors?

A
  • Wrong patient
  • Omission (non-treat)
  • Incomplete/unclear order
  • Wrong drug
  • Wrong time
  • Wrong dose
  • Wrong dosage form
  • PATIENT ALLERGY
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is name of the SYSTEM to prevent errors?

A

Computerized Physician Order Entry (CPOE)

Computerized provider order entry (CPOE) is an application that allows health care providers to use a computer to directly enter medical orders electronically in inpatient and ambulatory settings, replacing the more traditional order methods of paper, verbal, telephone, and fax.

  • Elims risk of incomplete or unclear written orders that may be misinterpret
  • Most systems contain clinical decision support tools
  • Algorithms and prompts that guide ordering provider to select approp drug, dose, frequency while checking for allergies and interactions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Other ways to prevent errors?

A

1) Preprinted order forms
2) Standardized forms will already contain many elements of appropriate order
o When take verbal or telephone orders: transcribe, read back, confirm
o Must follow these steps. Do NOT read back then transcribe
3) Tall Man lettering. Often built into systems
4) If ANY doubt about an order (written, verbal, electronic) CONFIRM w/prescriber

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is Medication Reconciliation and when needed?

A

Changes often occur when patients TRANSITION from one level of care to another. Creates environ that facilitates medication errors.

  • Medication reconcile is process of review medication list against medical records
  • Technicians should pay attention to prescription and nonprescription medications, alternative medics, dietary supps (herbs, vit/minerals)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Preventing errors during prescribe or order (common errors)

A
AD, AS, AU – confuse w/ OD, OS, OU	
CC for cubic centim.  Use mL instead	
D/C  - for discharge or discontinue	
HS – for half-strength or “at bedtime”
IU – for international unit	
Ug – for micrograms	
MS, MSO4, MgSO4 – for morphine sulfate or magnesium sulfate	
Q.D – for every day
Q.O.D. – for every other day	
SC or SQ – for subcutaneous	
T.I.W. – for 3x/week	
U – for units (spell word instead
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is Root Cause Analysis (RCA)?

A

A structured method that is used to analyze serious adverse events. Focuses on underlying probs that increase likelihood of errors while avoid focus on mistakes by individs.

17
Q

Key steps in RCA?

A

1) Data Collection (review of records and interviews)
2) Reconstruction of timeline of processes and events
3) Analysis of processes and events by multidiscipline team
4) ID of active errors (error by humans interact w/system)
5) ID of latent errors (hidden problems)
6) Elimination of systems architect that lead to ID’d latent errors

18
Q

Why Reporting of Adverse Drug Events (ADEs) important?

A
  • Clinical trials that conduct to achieve drug approval MAY NOT BE LARGE OR LONG ENUF to detect rare but serious side effects.
  • There have been many high-profile cases where drugs have been remove from the market or highly restrict Only After Years Of Post-Mktg Data Show Safety Concerns.
19
Q

Who has oversight on report of adverse drug events?

A

FDA HAS MEDWATCH SYSTEM, should be used to report any ID adverse drug events. These include:

  • Unexpect side effects or adverse events
  • Product qual problems
  • Product use or other medication errors that can be prevented
  • Therapeutic failures

Medwatch – report directly to FDA thru this monitor system. VOLUNTARY REPORTING SYSTEM. For report issues w/prescription and OTC meds, biologics, med devices, combo prods, special nutrition prods, cosmetics, foods and bevs.

20
Q

Where to report Vaccine related adverse event?

A

Vaccine related events should be report to Vaccine Adverse Event Reporting system (VAERS). THIS IS MANDATORY.
• Healthcare providers require by law to report:
o Adverse events list by vaccine manuf to be a contradiction to future doses of vaccine
o Selected adverse events list under each vaccine type on the VAERS website
• Healthcare providers are strongly encourage to report other adverse events occur after vaccine admin, regardless of if link to vaccine. Also vaccine admin errors.

21
Q

What is a Sentinel Event?

A

Patient safety events that result in DEATH, PERMANENT HARM, OR SEVERE TEMPOR HARM, AND INTERVENTION REQUIRE TO SUSTAIN LIFE, or “Unexpected occurrence involve death or serious physical/psycho injury, or risk thereof”, e.g. patient suicide, abduction of patient, etc.

Encouraged that these events be reported to the Joint Commission.

22
Q

What is reporting of Medication Errors system called, and what is required?

A

ISMP National Medication Error Reporting Program (ISMP MERP) is a VOLUNTARY reporting platform for healthcare professionals to report actual or potential med errors.
A vaccine error reporting system also available (ISMP VERP).

23
Q

What are Q’s and Issues that must be answer by Pharmacist?

A

1) Drug safety
Qs: a) Adverse effects (Can XX cause headache?), b) Allergies, c) Contraindications (Is XXX ok to take if I have high blood pressure?), d) Drug interacts (Can I take xx with yy?), e) Pregnancy and Lactation Qs

2) Dosing/Administration
a) Dose (What dose of XXX should I give patient?), b) Frequency, c) Duration (How long take?), d) Route (Can morphine be taken subcutaneously – under skin?), e) Special Instructs, f) Compatibility – can XX and YY be infuse in same IV line?

3) Interchangeability “What can be used to treat XXX instead of drug YYY?; Any issues using generic?”
4) Therapeutic uses: Can clonidine be used for ADHD?

5) Monitoring: Interpret of lab values, vital signs.
6) Drug misuse or adherence issues
7) Drug Utilize review

24
Q

What is DUR?

A

DRUG UTILIZATION REVIEW (DUR)

MUST be done by pharmacist. Changes in drug therapy MAY BE NECESS based on DUR results.

Done on EVERY prescription.

ADEs checked during DUR.

Techs may encounter a DUR rejection code when process a prescription order in the pharmacy info system.

1) Review DUR in coordinate w/pharmacist
a. Override DUR in system if approp and allowable.
b. Contact prescriber to address med prob if needed
c. Submit prior auth or contact prescriber to submit prior auth form if require
2) After above, process medication order

25
Q

What are issues that should be evaluate by designated personnel prior to enter non-sterile compounding areas?

A

o Rashes
o Sunburn
o Recent tattoos, oozing sores
o Conjunctivitis

26
Q

What are key prepare steps for compounding drugs?

A

1) Maintain hand hygiene
o Wash hands frequent during work, also when enter/exit compound areas
o Keep nails trim and clean

2) Ensure clothing is clean and appropriate for compound area

3) Remove items not easily cleanable or that may interfere with garbing, including:
o Outer garments
o Hand, wrist, or other exposed jewelry that may interfere w/gloves and gowns
o Headphones, earphones, earbuds
o Artificial nails

27
Q

What are common Personal Protective Equipment (PPE)? How and when used?

A
  • Gloves: MUST be worn for all compounding activities.
  • Gown, hair, facial hair coverings, shoe cover generally appropriate as well. Gowns can be used same shift IF NOT SOILED. Other covers/gloves SINGLE USE ONLY.
  • Googles/respirators should be clean w/isopropyl alcohol.
  • Visible soiled PPE – should be changed immediately.
  • PPE reqs for hazardous substances should always be follow.
28
Q

What are regulations re Cleaning and Sterilizing Nonsterile compounding areas?

A

(Proposed changes to USP GENERAL CHAPTER 795 are to recco the following):

  • Floors: DAILY, after spills, and when surface contamination is known/suspected
  • Containment Ventilated Enclosures (containment hoods) and countertops: at BEGIN/END OF EACH SHIFT, after spills, and when surface contamination is known/suspected. Clean and sanitize horizontal work surface of CVE between compound of different drugs.
  • Equipment used in compounding operations: Before 1st use and thereafter in accord w/manuf’s reccos. IF NO RECCO AVAILABLE, AFTER EACH USE.
  • Clean should be done w/70% ISOPROPYL ALCOHOL
  • Ceilings, storage shelving, walls: EVERY 3 MONTHS, after spills, and when surface contaminate is known/suspected.