Patient Eligibility Flashcards
1
Q
A patient is eligible for MS-2 Step if:
A
- She has made an informed voluntary choice to have an MTOP.
- Her pregnancy is no more than 9 weeks.
- She has no medical contrindications to MS-2 Step.
- She meets the legal requirements for termination of pregnancy in the Australian State where it is provided.
2
Q
When is MS 2-Step contraindicated?
A
- Lack of access to emergency medical care 14 days after the start of treatment.
- Suspected or confirmed ectopic pregnancy
- IUD.
- Uncertainty about gestational age.
- Chronic adrenal failure.
- Diseases that require exogenous steroid administration (e.g. asthma that is uncontrolled by treatment)
- Known Haemorrhagic disorders.
- Treatments with anticoagulants.
- Known hypersensitivity to MS-2 Step.
- Contraindications to mifepristone and misoprostol.
3
Q
If you have symptoms of a pelvic infection what do you need to do before taking MS-2 step?
A
Treat it.
4
Q
Who can safely be offered MS-2 Step?
A
- Women who have had a C-section in the past.
- Women who have multiple gestations.
- Obesity
- Uterine abnormalities like fibroids.
5
Q
Mifepristone is not recommended in patient with:
A
- Cardiovascular Disease
- Hypertension
- Hepatic Disease
- Renal Disease
- Respiratory Disease
- Diabetes
- Severe Anaemia
- Malnutrition
- Heavy Smokers.
6
Q
If you have an IUD, what should you do?
A
Remove it before taking the MS 2-Step.
7
Q
If you are taking inhaled steroids what can happen?
A
They can lose their effectiveness for a 3-4 day period whilst Mifepristone Linepharma starts working.
(It has antiglucocorticoid effects)
8
Q
What are the potential drug interactions for Mifepristone?
A
Mifepristone is metabolised by the P450 enzyme CYP3A4. (But there is no evidence of yet of any drug interactions)
- Inhibitors
- Ketoconazole
- Itraconazole
- Erythromycin
- Grapefruit juice.
- Inducers
- Rifampicin
- Dexamethasone
- St John’s Wort
- Anticonvulsants.
