Pathophysiology of Thrombosis and Embolism Flashcards
How can blood flow be abnormal?
Can be stasis or Turbulent
Stasis blood flow?
Stagnant blood flow because something is obstructing the blood flows path.
Turbulent blood flow?
Forceful and unpredictable blood flow
What causes defects in blood flow?
- Commonly may be caused by thromboembolism
- Other causes includes: Atheroma, Hyperviscosity (blood is too thick), spasm of vessels, external compression (such as a tumour oppressing the blood vessel), vasculitis (inflammation of the blood vessel wall, vascular steal
What is the Virchows Triad ?
This gives us answers on thrombolism and embolism. It includes
- Changes in blood vessel walls
- Changes in blood constituents
- Changes in pattern of blood flow
Virchows triad gives the factors which cause thrombosis.
What is thrombosis ?
Thrombosis is defined as a formation of a solid mass from the constituents of blood within the vascular system during life. It is in the VESSEL! It is not the same as clot
Pathophysiology of thromosis?
Change in vessel wall will be causes by enfothelial injury. Then there should be stasis or turbulent flow. Hypercoagulity of the blood will be an important factor.
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