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MSY2 MHD/Pharm Exam 4 > Pathophysiology of CHF > Flashcards

Pathophysiology of CHF Flashcards

1
Q

Briefly review the determinants of cardiac performance in isolated cardiac muscle and the
normal, intact heart:

A

a

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2
Q

Discuss the pathophysiology of congestive heart failure + reduced ejection fraction:

A

d

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3
Q

Discuss the pathophysiology of congestive heart failure + preserved ejection fraction:

A

d

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4
Q

What are some of the compensatory mechanisms activated in response to myocardial dysfunction (3):

A

Frank-Starling Mechanism
Neurohormonal Alterations
Ventricular Hypertrophy and Remodeling

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5
Q

Discuss the compensatory mechanisms activated in response to myocardial dysfunction: Frank-Starling Mechanism

A

s

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6
Q

Discuss the compensatory mechanisms activated in response to myocardial dysfunction: Neurohormonal Alterations

A

f

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7
Q

Discuss the compensatory mechanisms activated in response to myocardial dysfunction: Ventricular Hypertrophy and Remodeling

A

f

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8
Q

Briefly discuss the clinical manifestations of heart failure

A

Left-sided HF:

Symptoms -Dyspnea, orthopnea, paroxysmal nocturnal dyspnea, cough, fatigue

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9
Q

Review: How does an increase in ventricular afterload reduce cardiac output?

A

d

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10
Q

Review: How does an increase in ventricular preload increase cardiac output?

A

d

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11
Q

Review: how does sympathetic stimulation increase cardiac output in the normal heart?

A

d

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12
Q

Review: how does sympathetic stimulation increase cardiac output in the failing heart?

A

d

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13
Q

Review: What is the pathophysiological basis for HRrEF?

A

d

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14
Q

Review: what is the pathophys basis for HRpEF?

A

d

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15
Q

Review: what are the common symptoms of left-sided congestive heart failure?

How do they relate to the pathophys of CHF?

A

d

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16
Q

Review: How is the RAAS actuely beneficial in maintaining cardiac output?

Why does RAAS actiation ultimately prove deleterious?

A

d

17
Q

Review: what is meant by the term “ventricular remodeling” ?

A

d

MSY2 MHD/Pharm Exam 4 (5 decks)

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