Pathophysiology of cardiovascular disease

Question 1

Cardiac disease prevalence

Neoplastic disease is no. 1 though

Answer 1

11% of dogs- increases with age

Question 2

Findings- clinical signs = heart failure

Answer 2

Heart murmurs
breathlessness
coughing

Question 3

Heart Failure

Answer 3

inadequate CO with normal BP= forward failure

Adequare CO with abrnomral filling pressure = congestive/backwards failure

can have both

Question 4

How does heart failure occur

Answer 4

Inadequacy of blood inot arteries- initiates adaptions to restore arterial filling
1. Pump Failure
2. Vol. overload (most common in dogs)
3. Mitral Insuffiiency
4. Pressure overload
5 arrythimias
6. Diastollic failure

Question 5

NC-ProBNP marker

Answer 5

released in response to high pressure/ too much fluid retention. (maladaption)

marker of heart disease in cats

Question 6

Heart Hypertrophy

Answer 6

vol overload- eccentric hypertrophy.

pressure overload- concentric hypertropy

Good to begin with but can outgrow blood supply,