Pathology Random

Question 1

Virchow’s triad of thrombosis

Answer 1

Endothelial injury
Turbulent blood flow (stasis)
Hypercoagulable blood

Question 2

Platelet activation

Answer 2

Activated platelets are more sticky
Attract and aggregate with other platelets
Aggregate with fibrin
Fibrin in end point of coagulation cascade

Question 3

Uh, this is on a slide called Technical Stuff on platelet aggregation.

Answer 3

Endothelium is lost, so underlying collagen exposed

Collagen binds to glycoprotein Ia (and here we lost the slide)

Question 4

Likely spots to find occlusion

Answer 4

Branching of arteries
Just above aorta
Coronary arteries

Question 5

Where does most stasis occur?

Answer 5

Deep venous system

Faulty valves

Question 6

What can cause hypercoaguability

Answer 6

Increased viscosity:
Dehydration
Polycythemia
Leukaemia

Question 7

Inherited disorders causing hypercoaguability

Answer 7

Factor V Leiden

Protein C deficiency
Protein S deficiency
Antithrombin III deficiency

Question 8

Other causes of emboli in blood

Answer 8

Tumour emboli
Air and amniotic fluid after birth
Septic in PWID
Fat emboli after accident (bone fat into open blood vessels)