Pathology Pt 2 Flashcards
Which of the following is least likely to be associated with the acute onset of 3 blue toes?
A. DVT formation in the popliteal and calf veins
B. popliteal aneurysm
C. recent angiography procedure
D. abdominal aortic aneurysm
A
FeedBack:Blue toe syndrome occurs due to distal embolism from a recent invasive procedure, atherosclerotic plaque or thrombus in the aorta or lower extremity artery.
Longitudinal images are presented of the anterior abdomen just superior to the umbilicus. What is the most common cause of the abnormality seen on the images?
A. portal HTN
B. polycythemia vera
C. malignant HTN
D. pulmonary HTN
A
FeedBack:A patent umbilical vein is identified on the images. Severe portal HTN will cause the umbilical vein to recanalize, allowing retrograde filling to occur within the vessel.
Significant atherosclerotic disease found in which artery could lead to male impotence?
A. common iliac or internal iliac
B. common iliac or external iliac
C. common femoral or profunda femoral
D. external iliac or common femoral
A
FeedBack:Disease in the common iliac and internal iliac artery can lead to ischemia of the penile tissues.
Numbness and tingling in the extremities is summarized by what term listed below?
A. Paralysis
B. Paresis
C. Paresthesia
D. Pallor
C
FeedBack:Paresis refers to the partial loss of movement and feeling of an extremity/body part. Paralysis refers to the complete loss of movement and feeling of an extremity of body part. Pallor refers to a pale white color of the skin.
All of the following correctly describe compartment syndrome, except:
A. all forms of compartment syndrome are considered an emergency
B. most commonly occurs due to trauma
C. can occur in the leg or arm
D. prevents blood flow in and out of surrounding tissues
A
FeedBack:Acute compartment syndrome is an emergency, but chronic compartment syndrome is not an emergency. The acute onset of compartment syndrome is usually associated with trauma and a broken leg or arm. Increased pressure in the osteofascial compartment will prevent blood flow in and out of surrounding tissues. This can cause permanent muscle and nerve damage.
Which of the following describes chronic lower extremity DVT?
A. pulsatile flow pattern
B. echogenic vein walls
C. vein is completely non-compressible
D. varicocele formation
B
FeedBack:Chronic thrombus formation can cause the vein walls to appear thickened and echogenic. It can also lead to partial compressibility of the vein and continuous flow in the vessel.
A patient presents with a prior history of popliteal DVT and a recent history of intermittent mild leg pain with increasing appearance of small varicosities on the calf. Which statement below best describes his condition?
A. The patient is suffering from secondary varicose vein formation.
B. There is most likely a clot in the gastrocnemius veins of the calf.
C. The patient most likely has a recurrent acute DVT.
D. There is most likely a Baker’s cyst in the popliteal fossa causing extrinsic compression.
A
FeedBack:Primary varicosities form due to abnormal valves in the superficial venous system. Secondary varicosities form if there is an associated problem in the deep system, such as previous DVT.
Proximal to a DVT in the femoral vein, the flow appears very slow and visible on 2D imaging. The red blood cells appear lined up or stacked in rolls. What is this phenomenon called?
A. May-Thurner Syndrome
B. Rouleaux Formation
C. Phlegmasia cerulea dolens
D. Raynaud phenomenon
B
FeedBack:Proximal to a DVT in the superficial femoral vein, the flow appears very slow and visible on 2D imaging. The red blood cells appear lined up or stacked in rolls. This phenomenon is called Rouleaux formation.
Which of the following is associated with CREST syndrome?
A. Secondary Raynaud phenomenon
B. Superficial phlebitis
C. Primary Raynaud disease
D. Aortic aneurysm
A
FeedBack:In contrast to Raynaud disease, Raynaud phenomenon presents concurrently with CREST syndrome, in which tissue necrosis results from spastic and occlusive disease. CREST syndrome involves symptoms of generalized calcinosis, Raynaud phenomenon, esophageal dysfunction, scleroderma, and telangiectasia.
Which of the following vessels supplies blood to a carotid body tumor?
A. ICA
B. subclavian
C. ECA
D. MCA
A
FeedBack:Coarctation causes a ridge of tissue that blocks flow, usually in the descending aorta. This causes monophasic flow with increased antegrade diastolic flow. Brachial pressures will be normal but the bilateral ankle pressures will be decreased.
A 55yr old with a history of alcoholism, jaundice and cirrhosis is referred for a liver Doppler exam. All of the following are commonly associated findings, except
A. portal thrombosis
B. dilated umbilical vein
C. dilated coronary vein
D. decreased resistance in the hepatic artery
D
FeedBack:Resistance in the hepatic artery will increase with the increase in resistance to flow in the cirrhotic liver tissue. The coronary vein (AKA left gastric vein) and the umbilical vein will dilate with significant portal HTN.
All of the following correctly describes Buerger disease, except?
A. commonly associated with collagen disease
B. associated with males that are heavy smokers
C. also known as thromboangiitis obliterans
D. most commonly presents as multiple painless, wet, oozing ulcers of the feet and ankles
D
FeedBack:Buerger Disease/Thromboangiitis Obliterans is an occlusive disease of SMALL to MEDIUM size arteries caused by inflammation of arterial wall and surrounding connective tissue. It is always associated with heavy smoking. It is most common in men, age 20-30 years. Collagen disease, such as lupus, is usually associated with Buerger disease. The disease first affects the plantar or palmar arteries then moves centrally. Common symptoms include ischemic rest pain and distal dry, painful ulcers. Evaluation can be performed by Duplex and PPG techniques.
Arterial claudication occurs:
A. distal to the obstruction
B. while the patient is resting
C. while the legs are in the dependent position
D. proximal to the obstruction
A
FeedBack:Arterial claudication occurs distal to the hemodynamically significant obstruction.
Which of the following is a congenital vascular abnormality that commonly causes decreased ankle pressures bilaterally?
A. Coarctation of the aorta
B. Budd Chiari Syndrome
C. Thoracic Outlet Syndrome
D. CHF
A
FeedBack:Coarctation causes a ridge of tissue that blocks flow, usually in the descending aorta. This causes monophasic flow with increased antegrade diastolic flow. Brachial pressures will be normal but the bilateral ankle pressures will be decreased.
Which of the following terms would be used to describe flow identified just proximal to a 95% ICA stenosis?
A. laminar
B. damped
C. low resistance
D. tardus parvus
B
FeedBack:Pre-Stenotic Zone: Increased resistance and resistive index, Flow velocity may be dampened with loss of diastolic flow, Short acceleration time
If the left proximal CCA demonstrates a PSV of 35cm/s and the right proximal CCA demonstrates a PSV of 115cm/s, which of the following could explain the findings?
A. aortic valve stenosis
B. decreased hematocrit levels
C. congestive heart failure
D. left ICA occlusion
D
FeedBack:If a single CCA demonstrates elevated velocity = tortuosity on that side or compensatory flow due to obstruction in the other carotid system. If the left ICA is occluded, flow in the CCA will be low velocity with a quick upstroke and little to no diastolic flow. The right CCA velocity can increase as it tries to provide the additional cerebrovascular flow needed. The left vertebral artery may also demonstrate elevated velocity as it tries to compensate for the ipsilateral ICA occlusion. The other choices would cause bilateral hemodynamic changes.
Fibromuscular dysplasia most commonly affects which portion of the carotid arteries?
A. CCA bifurcation
B. bulb and proximal ICA
C. mid segment of the ICA
D. proximal ECA
C
FeedBack:FMD usually occurs in the mid or distal segment of the ICA, while atherosclerosis most commonly affects the proximal ICA.
You perform a bilateral venous Doppler due to bilateral swelling and pain in the legs. Both common femoral vein waveforms look like the tracing on the image. Which of the following is least likely to cause the flow changes?
Image of spectral Doppler is of pulsatile venous flow
A. congestive heart failure
B. severe tricuspid regurgitation
C. venous hypertension
D. IVC obstruction
D
FeedBack:Cardiac pulsatility in the lower extremity veins can be related to venous HTN. This is caused by CHF, renal dysfunction and severe tricuspid regurgitation.
Which of the following is least likely to cause a decrease in digit pressures of the upper extremity?
A. Buerger disease
B. SVC syndrome
C. Raynaud disease
D. Thoracic outlet syndrome
B
FeedBack:Raynaud, TOS, Buerger disease and atherosclerosis can all lead to abnormally low digit pressures and abnormal PPG tracing.
Patients with lower extremity arterial disease may describe pain
A. that is relieved by lying down
B. that is relieved by elevating the legs
C. that is relieved by walking
D. that is relieved by placing legs in a dependent position
D
FeedBack:The dependent position helps blood to reach the lower legs more quickly. Walking and elevating the legs would increase the pain. Lying down would provide minimal relief due to the loss of gravity’s assistance with the flow.
What is the most common symptom of peripheral arterial disease?
A. claudication
B. rest pain
C. decreased pedal pulses
D. ulceration
A
FeedBack:Claudication is the most common symptom of peripheral arterial disease.
If the tibioperoneal trunk is occluded, flow in which calf vessel(s) will not be decreased?
A. anterior tibial artery
B. posterior tibial artery
C. peroneal artery
D. posterior tibial artery and peroneal artery
A
FeedBack:The popliteal artery bifurcates into the anterior tibial artery and tibioperoneal trunk just outside the popliteal artery. Slight distal to that bifurcation the trunk splits into the posterior tibial artery and peroneal artery.
Blue Toe Syndrome can be a complication of which of the following?
A. Abdominal aortic aneurysm
B. Deep venous thrombosis
C. Thoracic outlet syndrome
D. Raynaud Phenomenon
A
FeedBack:Blue toe syndrome is caused by emboli reaching the small digital arteries and causing obstruction/ischemia. The ischemic toe tissue becomes discolored and cyanotic in appearance. AAA formation usually leads to thrombus accumulation in the affected area of the vessel. This thrombus poses a risk of emboli formation and distal ischemia.
The Scimitar sign is associated with:
A. Median arcuate ligament syndrome
B. Adventitial cysts
C. Bovine arch
D. Femoral to Femoral bypass graft
: B
FeedBack:The Scimitar sign is associated with adentitial cyst formation. The arterial lumen is compressed by the cyst and is said to look like a scimitar (type of curved sword).
Which of the following describes the path of an embolus?
A. a small piece of soft plaque breaks off from the carotid bulb and floats toward the brain
B. a small piece of thrombus breaks off from a thrombus in the left ventricle and floats toward the lungs
C. a small piece of soft plaque breaks off from the carotid bulb and floats toward the lungs
D. a small piece of thrombus breaks off from a thrombus in the right ventricle and floats toward the brain
A
FeedBack:An embolus is a floating piece of debris, air bubble, thrombus or plaque that moves distally until it lodges in a small vessel. Thrombus in the right ventricle will be sent to pulmonary artery and the lungs = pulmonary embolism. Thrombus in the left ventricle can be sent to the brain through the aorta = stroke. An embolus in the carotid system will go to the brain.
Paresthesia is defined as:
A. dizziness related to change in patient position
B. loss of vision in one eye for a short period of time
C. loss of ability to move an extremity or other body part
D. an abnormal skin sensation, such as numbness or tingling
D
FeedBack:Paralysis is defined as loss of ability to move an extremity or other body part. Paresthesia refers to an abnormal skin sensation, such as numbness or tingling.
A patient presents with gangrene of the foot and toes. The most likely cause of these symptoms is:
A. a 5cm aortic aneurysm with mural thrombus
B. chronic occlusion of the popliteal artery
C. extensive deep and superficial vein thrombosis
D. coarctation of the aorta
C
FeedBack:Venous gangrene usually involves the foot and all toes, while arterial gangrene usually involves one or two toes.
Which of the following statements regarding venous ulceration is false?
A. Venous ulcerations are most commonly located on the medial calf/ankle area.
B. Venous ulcerations are usually very painful.
C. Venous ulcerations are usually wet and oozy.
D. Most venous ulcers can be treated and resolved.
B
FeedBack:Venous ulcerations are not reported as causing pain in majority of cases. Arterial ulcerations are very painful due to tissue ischemia and necrosis. Most venous ulcerations can heal once the venous insufficiency issue has been corrected. (stockings, laser, surgery etc)
Which of the following risk factors has the highest incidence of lower extremity thrombus formation?
A. Diabetes
B. Polycythemia vera
C. Rotator cuff repair
D. Recent hip surgery
D
FeedBack:Patients who have undergone any type of lower extremity surgery are at the greatest risk of DVT. Usually these patients are confined to a bed for several days/weeks which leads to stasis. There are significant limitations with using blood thinners immediately following surgery because it would prevent the healing of the surgery and could lead to hemorrhage.
A patient presents with a swollen left leg from hip to ankle and the right leg is normal. A US exam shows compressible vessels bilaterally. Doppler demonstrates normal flow in right, leg but there is loss of phasicity of flow and decreased augmentation of the left common femoral vein and proximal femoral vein. Which of the following is/are a potential diagnosis?
A. left ovarian mass and left external iliac thrombosis
B. right external iliac thrombosis and IVC thrombosis
C. bilateral external iliac and internal iliac thrombosis
D. IVC thrombosis
E. bilateral external iliac thrombosis
A
FeedBack:IVC thrombosis would cause flow abnormalities in both extremities. Internal iliac thrombosis will not affect the venous outflow of the legs.
Adventitial cysts:
A. are more common in women
B. most commonly affect the popliteal artery
C. are a normal variant that can be seen in up to 10% of patients
D. are usually treated with bypass graft placement
B
FeedBack:Adventitial cysts are a rare condition that involves the collection of mucinous material within the adventitial wall layer of the affected vessel. They predominantly affect the peripheral arteries with the popliteal artery most commonly affected. The cysts are most common in young to middle-aged men. The can be treated by ultrasound guided cyst aspiration.
Venous gangrene usually involves ____________________________, while arterial gangrene usually involves________________________.
A. the foot but no toes, the toes but not the foot
B. all the toes and foot, just one or two toes
C. right foot, left foot
D. just one or two toes, all the toes and foot
B
FeedBack:Venous gangrene usually involves the foot and all toes, while arterial gangrene usually involves one or two toes.
A venous insufficiency exam is performed for a patient with multiple varicosities. The deep system is found to be competent, but there is insufficiency present in the great saphenous vein. Which of the following statements regarding the findings is true?
A. There are secondary varicosities present but compression stockings are not an option for treatment for this patient.
B. There are primary varicosities present.
C. There are secondary varicosities present.
D. Compression stockings are not an option for treatment for this patient.
B
FeedBack:Varicosities with superficial venous insufficiency related to deep venous system disease = secondary varicosities Varicosities with incompetent valves causing superficial venous insufficiency and normal deep system = primary varicosities Compression stockings are usually the first step in treatment for all varicosities.
A 54yr old male presents with a moderately swollen right leg, from the upper thigh down to the ankle. He states that the leg started to swell 3 days ago. He first noticed it when he returned home from the airport following a recent vacation to Indonesia. What is the most likely cause of his symptoms?
A. Acute DVT in the femoral vein
B. Acute DVT in the popliteal vein
C. Superficial phlebitis in the great saphenous vein caused by infection
D. Chronic DVT in the femoral vein with onset of cellulitis
A
FeedBack:Superficial phlebitis would not lead to moderate leg swelling. Chronic DVT would not create an acute symptom. His recent history of a long flight to Indonesia increases his risk for Acute DVT formation due to stasis. Acute DVT in the popliteal vein would cause swelling of the lower leg only.
Which of the following can cause overestimation of stenosis in the carotid artery?
A. polycythemia vera
B. congestive heart failure
C. aortic regurgitation
D. compensatory flow
D
FeedBack:When there is a significant stenosis or an occlusion in one carotid system, the carotid system on the other side can aid in feeding both sides of the brain. Flow velocities in the contralateral carotid system will be elevated. For example, if there is a left CCA occlusion, the velocities in the right CCA, ECA and ICA can increase with compensatory flow. If there is also a carotid stenosis on the right side, the stenosis can be overestimated using velocity criteria because the velocities are falsely elevated due to compensatory flow.
Venous flow proximal to an AV fistula becomes ________________ due to the inflow of arterial flow distally
A. phasic
B. high resistance
C. pulsatile
D. continuous
C
FeedBack:Venous flow proximal to an AV fistula becomes pulsatile due to the inflow of arterial flow distally.
You are performing a venous Doppler exam due to the recent onset of swelling in the left calf. The mid left femoral vein appears to be occluded by hypoechoic, non-compressible thrombus. The popliteal vein is completely compressible. Which of the following Doppler waveform characteristics is expected from the popliteal vein?
A. normal response to distal augmentation of calf muscle
B. decreased response to distal augmentation of calf muscle
C. loss of respiratory phasicity
D. increased pulsatility
C
FeedBack:The flow response to the distal augmentation would most likely be decreased but NEVER augment a patient’s calf when an acute DVT is diagnosed. The best answer is loss of respiratory phasicity because continuous flow is expected with the proximal obstruction.
A varicose vein is usually:
A. a dilated vessel of the perforator system.
B. a dilated lesser saphenous vein.
C. a dilated tributary of the deep system.
D. a dilated tributary of the greater saphenous vein.
D
FeedBack:The greater saphenous vein and associated tributaries are most commonly associated with varicosity formation.
If there is a 75% stenosis of the distal superficial femoral artery, which of the following arteries will demonstrate a monophasic waveform?
A. peroneal and posterior tibial
B. posterior and anterior tibial
C. anterior tibial only
D. posterior tibial, peroneal and anterior tibial
D
FeedBack:A 75% stenosis in the SFA will cause a significant loss of flow distally. The resistance in the distal vessels will drop and the waveforms will become monophasic.
An aortic dissection most commonly originates:
A. in the infrarenal descending aorta
B. in the descending thoracic aorta, just distal to the origin of the left subclavian artery
C. in the aortic root
D. in the ascending aorta
B
FeedBack:Aortic dissection most commonly occurs in the descending thoracic aorta, just distal to the origin of the left subclavian artery. The ascending aorta and arch are the second most common sites for dissection.
Which of the following would lead to overestimation of stenosis in the internal carotid artery?
A. Tandem stenosis
B. Reduced systemic blood pressure
C. Compensatory flow due to stenosis on other side
D. Significant aortic valve stenosis
C
FeedBack:Overestimation of stenosis in the ICA can be seen with:
Systemic HTN
Compensatory flow due to stenosis on other side
Short area of focal stenosis
Smaller vessel size
Elevated heart rate
Measuring a compensatory heart beat with arrhythmias
The most common cause of hemodialysis graft failure is ________________.
A. thrombus formation
B. acute rejection
C. arterial stenosis
D. anastomosis rupture
A
FeedBack:The most common cause of hemodialysis graft failure is thrombus formation.
Which of the following portions of the leg would be swollen with chronic insufficiency?
A. calf only
B. ankle and calf, but not the foot
C. foot and ankle, but not the calf
D. calf, foot, ankle
B
FeedBack:Swelling of the feet normally does not occur with venous disease (systemic or cardiac disease, yes)
Which of the following is not considered a risk factor for peripheral arterial disease?
A. Smoking
B. Systemic HTN
C. Pregnancy
D. Diabetes
C
FeedBack:Pregnancy can lead to an increase in venous blood volume and stasis but has no effect on the formation of arterial disease.
Which of the following will result in a low resistance ECA waveform with increased antegrade flow in diastole?
A. contralateral ICA occlusion
B. temporal arteritis
C. contralateral subclavian stenosis
D. ipsilateral mid CCA stenosis
D
FeedBack:The ECA normally demonstrates a high resistance flow pattern with minimal antegrade diastolic flow. Stenosis proximal to the ECA (in the CCA) or in the proximal ECA will cause lower resistance ECA flow with increased antegrade flow in diastole. If the ipsilateral ICA is occluded, these same changes will occur.
Instep claudication is a symptom that is most commonly related to:
A. Thoracic outlet syndrome
B. Thromboangiitis Obliterans
C. Peripheral arterial disease
D. Raynaud’s syndrome
B
FeedBack:TAO refers to occlusive disease of SMALL to MEDIUM size arteries caused by inflammation of arterial wall. The disorder is always assoc. w/ heavy smoking and commonly presents with instep claudication.
A damped waveform with low velocity turbulent systolic flow will be found:
A. at the stenosis site
B. distal to a significant stenosis
C. proximal to a significant stenosis
D. in a normal PTA tracing
B
FeedBack:Distal to the site of stenosis, the blood flow will be lower velocity than at the stenosis. Turbulence will also cause spectral broadening.
What is caput medusa?
A. tortuous vessels around the umbilicus caused by portal HTN
B. lower extremity varicosities on the anterior thigh
C. formation of gastroesophageal varices caused by portal HTN
D. lower extremity varicosities on the anterior knee
A
FeedBack:Caput medusa refers to dilated, tortuous vessels around the umbilicus caused by portal HTN.