Pathology Pg 775 Chart Flashcards
Osteoid Osteoma
Location
Metaphysis of femur and tibia
Osteoma
Location
Facial bones, skull
Osteoblastoma
Location
Vertebral column
Primary osteosarcoma
Location
Metaphysis of distal femur, proximal tibia, and humerus
Secondary Osteosarcoma
Location
Femur, humerus, pelvis
Osteochondroma
Location
Metaphysis of long tubular bones
Enchondroma
Location
Small bones of hands and feet
Chondrosarcoma
Location
Bones of shoulder, pelvis, proximal femur and ribs
Giant Cell Tumor
Location
Epiphysis of long bones
Ewing sarcoma
Location
Diaphysis and metaphysis
Osteoma
Age
40-50
Osteoid Osteoma
Age
10-20
Osteoblastoma
Age
10-20
Primary Osteosarcoma
Age
10-20
Secondary Osteosarcoma
Age
> 40
Osteochondroma
Age
10-30
Enchondroma
Age
30-50
Chondrosarcoma
Age
40-60
Giant Cell Tumor
Age
20-40
Ewing Sarcoma
Age
10-20
Osteoma
Morphology
Exophytic (grows out) growths attached to bone surface;
histologically similar to normal bone
Osteoid Osteoma
Morphology
Cortical tumors, characterized by pain;
hisotlogic pattern consisting of interlacing trabeculae of woven bone
Osteoblastoma
Morphology
Arise in vertebral transverse and spinous process;
histologically similar to osteoid osteoma
Primary osteosarcoma
Morphology
Grow outward, lifting periosteroum, and inward to the medullary cavity;
microscopy shows malignant cells forming osteoid;
cartilage also may be present
Secondary Osteosarcoma
Morphology
Complications of polyostotic Paget disease;
histologically similar to primary osteosarcoma
Osteochondroma
Morphology
Bony excrescences with a cartilaginous cap;
may be solitary or multiple and hereditary
Enchondroma
Morphology
Well-circumscribed single tumors resembling normal cartilage;
arise within medullary cavity of bone;
uncommonly multiple and hereditary
Chondrosarcoma
Morphology
Arise within medullary cavity and erode cortex;
microscopy shows well-differentiated cartilage-like or anaplastic features
Giant Cell Tumor
Morphology
Lytic lesions that erode cortex;
Microscopy shows osteoclast-like giant cells and round to spindle-shaped mononuclear cells;
Most are benign
Ewing Sarcoma
Morphology
Arise in medullary cavity;
Microscopy shows sheets of small round cells that contain glycogen;
Aggressive neoplasm
