Pathology Of The Female Genital Tract Practical Class 1 Flashcards
Histology of the Ectocervix
Non-keratinising stratified squamous epithelium
Describe the histology of the endometrium during the secretory phase
Presence of the corpus luteum
Early secretory phase- day 15/16 show subnuclear/vacuolation (i.e clear spaces in a row)
Late secretory phase- long, tortuous endometrial glands contain luminal secretions ready for implantation
What is the name of a malignant smooth muscle tumour?
Leiomyosarcoma
How can abruptio placenta present?
Anterpartum haemorrhage
APH
Describe the histology of cells infected by HPV?
cells show clear cytoplasm
called KOILOCYTOSIS
CIN 1
precancerous or dysplastic cells involve the lower third of the epithelium.
CIN 2
two third of epithelium involved by dysplastic epithelium
CIN 3
Dysplastic cells involve the full thickness of the epithelium→ carcinoma in situ
Possible symptoms of cervical cancer?
- Post coital bleeding
- foul smelling discharge
- intermenstrual bleeding
- weight loss when advanced
Histology of cervical cancer
95% of cervical cancers are squamous cell carcinoma
Histology of TZ
metaplastic squamous epithelium
How SCC of the cervix typically classified?
can be well, moderate or poorly differentiated and this depends on the amount of keratin produced
What does the presence of the corpus luetuem signify?
secretory phase of endometrium
What is the corpus lutuem?
The collapsed Graafian follicle following the ovulation of the secondary oocyte
lives for 14 days and then becomes corpus albacians which doesnt produce any hormones
Submucosal fibroid uterus
under the endometrium
(leiomyoma)
