Pathology Nephrotic Diseases Flashcards

1
Q

Minimal Change Nephropathy

Clinical

A

Nephrotic Syndrome:

  • proteinuria
  • hypoalbuminemia
  • edema
  • hyperlipidemia
  • lipiduria
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2
Q

Minimal change nephropathy

morphological

A

No / minimal change

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3
Q

Minimal change nephropathy

pathogen

A

Unknown - circulatory factor

  • EM: foot process effacement
  • IF: negative
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4
Q

Minimal change nephropathy

Treat

A

Steroids

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5
Q

Minimal change nephropathy

prognosis

A

Good

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6
Q

FSGS

Clinical?

A

Nephrotic Syndrome

  • Proteinuria
  • Hypoalbunemia
  • Hyperlipidemia
  • Edema
  • Lipiduria
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7
Q

FSGS

Morph

A

Focal segmental Glomerular sclerosis

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8
Q

FSGS

Pathogenesis

A

Unknown - circulatory factor, hyperfiltration, hereditary forms

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9
Q

FSGS

Therapy

A

Steroids - high relapse rate

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10
Q

FSGS

Prognosis

A

Some progress to ESRD

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11
Q

FSGS

4 types

A

I. Idiopathic / hereditary (primary) FSGS
II. HIV associated
III. Heroin nephropathy
IV. Secondary FSGS (hyperfiltration)

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