Pathology Nephrotic Diseases Flashcards
1
Q
Minimal Change Nephropathy
Clinical
A
Nephrotic Syndrome:
- proteinuria
- hypoalbuminemia
- edema
- hyperlipidemia
- lipiduria
2
Q
Minimal change nephropathy
morphological
A
No / minimal change
3
Q
Minimal change nephropathy
pathogen
A
Unknown - circulatory factor
- EM: foot process effacement
- IF: negative
4
Q
Minimal change nephropathy
Treat
A
Steroids
5
Q
Minimal change nephropathy
prognosis
A
Good
6
Q
FSGS
Clinical?
A
Nephrotic Syndrome
- Proteinuria
- Hypoalbunemia
- Hyperlipidemia
- Edema
- Lipiduria
7
Q
FSGS
Morph
A
Focal segmental Glomerular sclerosis
8
Q
FSGS
Pathogenesis
A
Unknown - circulatory factor, hyperfiltration, hereditary forms
9
Q
FSGS
Therapy
A
Steroids - high relapse rate
10
Q
FSGS
Prognosis
A
Some progress to ESRD
11
Q
FSGS
4 types
A
I. Idiopathic / hereditary (primary) FSGS
II. HIV associated
III. Heroin nephropathy
IV. Secondary FSGS (hyperfiltration)