Pathology Lecture Flashcards
Define Pathology
Study of the structural and functional changes in cells, tissues and organs that underlie disease
Bridging discipline between the basic and clinical sciense
What is general pathology?
Focuses primarily on basic reactions of cells and tissues to abnormal stimuli that underlie all disease
What is special or systemic pathology?
Examines the specific responses of specialized organs and tissues to well defined stimuli (Organ systems)
What is the foundation of modern pathology?
All diseases are the results of visible cell abnormalities
What is the normal cell confined to?
A specific range of function based on its genetics, current status and complement of nutrients and enzymes
Define Etiology
Cause of the disease
Abnormal conditions or disease are caused
What are intrinsic or genetic factors?
Mutations in genes that encode for enzymes in certain pathway leading to a disease
What are acquired factors?
Infections, toxicities.
External cofactors that contribute to a disease
Define pathogenesis
Mechanisms of development for the disease
Refers to the sequence of events
What are morphological changes?
The structural changes that are induced in cells and tissues of the body by the disease process