Pathology Differentials Flashcards

1
Q

Large ulcerative lesions

A

GETSE
Granulomatous lesions (Crohns, syphilis, TB, deep fungal)
EBV mucosal ulceration
TUGSE (traumatic ulcerative granuloma of stromal eosinophilia)
Squamous cell carcinoma (HPV vs Non HPV)
Epithelial dysplasia

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2
Q

Mass on soft Palate

A

Salivary gland neoplasm (benign vs. malignant)
Lymphoma
Abscess
Peripheral nerve sheath tumor
Epithelial dysplasia
Squamous cell carcinoma
Sinonasal/Maxillary Tumor
Necrotizing Sialometaplasia

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3
Q

Peripheral nerve sheath tumors

A

Neuroma
Neurofibroma
Traumatic neuroma
Schwanomma
Perineuroma
Granular cell tumor

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4
Q

RO Mass of Jaws

A

Osteoma
Osteosarcoma
Chondrosarcoma
Osteoblastoma
Osteomyelitis with proliferative periostitis
Metastasis

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5
Q

RO Single Lesion

A

Condensing osteitis
Idiopathic sclerosing osteitis
Cementoblastoma
Osteoma
Cemento-ossifying fibroma
Osteosarcoma

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6
Q

RO Multiple Lesions

A

Pagets Dz
Osteomas (Gardner’s Syndrome)
Florrid Osseous Dysplasia
Fibrous Dysplasia

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7
Q

RL Posterior Mandible

A

GO MAC AP

Glandular Odontogenic Cyst
OKC
Odontogenic myxoma
Ameloblastoma
Central Giant Cell Lesions
Ameloblastic Fibroma
Primordial Odontogenic Tumor

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8
Q

RL Posterior Maxilla

A

GO MACoc

Glandular Odontogenic Cyst
OKC
Odontogenic Myxoma
Ameloblastoma
Calcifying Odontogenic Cyst

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9
Q

RL Single Lesion: Not Associated with a Tooth

A

MALLS, CO

OKC
Ameloblastoma
Langerhans Cell Histiocytosis
Lymphoma
Metastatic Disease
Central Giant Cell Lesions
Simple bone cavity

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10
Q

RL Single Lesion: Associated with a Tooth

A

CA DOLOP
Calcifying Odontogenic Cyst
Ameloblastoma
Dentigerous Cyst
OKC
Lateral Periodontal Cyst
Odontogenic Tumor
Periapical Cyst

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11
Q

RL Crossing Midline

A

MAGA.COM

Central Mucoepidermoid Carcinoma
Ameloblastoma
Glandular Odontogenic Cyst
Aneursymal Bone Cyst
Central Giant Cell Granuloma
OKC
Mets from Distant Sites

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12
Q

Multiple RL

A

NBC NBC M&M

Nevoid Basal Carcinoma Syndrome (Multiple OKCs)
Multiple Myeloma
Cherubism
Noonan
Brown’s Tumors of Hyperparathyroidism
Mets

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13
Q

Multilocular RL

A

AbcC.. 1, 2,3… GOAL

Glandular Odontogenic Cyst
OKC
Aneurysmal Bone Cyst
Langerhans Cell Histiocytosis
AV Malformation/Hemangioma
Central Giant Cell Lesions

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14
Q

Mixed RO/RL Lesions

A

DOC 2As, 4Cs and an M

Desmoblastic ameloblastoma
Osteosarcoma
Chondrosarcoma
Ameloblastic Fibroma
Adonmatoid Odontogenic Tumor
Central Ossifying Fibroma
Calcifying Epithelial Odontogenic Tumor (Pinborg Tumor)
Calcifying Odontogenic Cyst (Gorlin Cyst)
Cemento-ossifying Fibroma
Mets (prostate, breast, thyroid MC)

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15
Q

Central Giant Cell Lesions

A

Central Giant Cell Granuloma
Brown’s Tumor of Hyperparathyroidism
Noonan’s Syndrome
Cherubism
Metabolic Bone Disease (Renal osteodsytrophy)
Giant Cell Osteosarcoma
Giant Cell Tumor of the Bone

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16
Q

Ulcerative & Vesiculobullous Lesions

A

HELLPP

Herpetic Stomatitis
Erythema Multiforme (EM)/Steven Johnson Syndrome
Lichen Planus
Lupus
Pemphigus
Pemphigoid

GVHD (Graft v Host Dz)

17
Q

Fungal Infections

A

HAM are most common
Histoplasmosis
Aspergillosis
Mucormycosis

Uncommon:
Blastomycosis
Paracoccidiomycosis
Coccidiomycosis
Cryptococcisis

18
Q

Blue/Black/Brown Pigmented Lesions of Oral Mucosa

A

Single:
Amalgam Tattoo
Blue nevus
Melanotic macule
Mucosal melanoma

Multiple:
Ethnic pigmentation
Smoker’s melanosis
Endocrine disorder (Addisons - adrenal insufficiency)

19
Q

Sarcomas

A

Rhabdomyosarcoma
UPS (undifferentiated pleomorphic sarcoma)
Kaposi sarcoma
Ewing sarcoma
Angiosarcoma
Liposarcoma

20
Q

Multiple Ulcers

A

A PEARL

Apthous ulcers
Anemia induced ulcerative mucositis
Late stage herpes simplex
Immune mediated or autoimmune (i.e. pemphigus/pemphigoid)
Reaction to substances (EM, SJS, lichenoid reaction)

21
Q

Papillary/Verrucous Lesions

A

SVC HS

HPV related squamous papilloma
Verrucous xanthoma
Condyloma acuminatum
Heck’s disease: cobblestone fissured appearance multiple papillary lesions
Verrucous carcinoma
Sialdenoma papilloforma
Inflammatory papillary hypoplasia

22
Q

Leukoplakias Single Lesion

A

Hyperkeratosis
Epithelial dysplasia
SCC
Mucosal burn
Verruciform xanthoma
Oral hairy leukoplakia (associated with EBV)

23
Q

Leukoplakias Multiple Lesions

A

Lichen planus
White sponge nevus
Proliferative verrucous leukoplakia
GVHD
Lupus
Candidasis
Condyloma Lata

24
Q

Erythroplakias

A

Epithelial dysplasia
SCC
Vascular lesion (telangectiasia, hemangioma)
Erythematous candidasis
Mucosal atrophy

25
Q

Single Gingival Lesions

A

Pyogenic granuloma
Peripheral ossifying fibroma
Peripheral giant cell granuloma
Neurofibroma
Dental abscess
Peripheral odontogenic tumors
Mets

26
Q

Yellow Hue Lesions

A

Adipose tissue (lipoma, liposarcoma)
Lymphoma
Amyloid containing lesion
Verrucifom xanthoma
Keratin containing lesion (SCC, OK, lymphepithelial cyst)
Pus containing cyst

27
Q

Floor of mouth mass

A

Ranula
SCC
Salivary gland neoplasm
Dermoid or epidermoid cyst

28
Q

Tongue Mass

A

Granular cell tumor
Hemangioma
Lymphangioma
Salivary gland neoplasm
Lipoma
Liposarcoma