Pathology Conditions Flashcards

1
Q

What is the histological change in cholesteatoma\?

A

Iin the superior posterior middle ear causes dysplastic change from cuboidal epithelium to squamous epithelium

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2
Q

What type of pathogen usually causes otitis media

A

Viral

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3
Q

What cranial nerve is associated with vestibulr schwannoma

A

CN VIII

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4
Q

If there is bilateral vestibular schwannoma in a patient e.g both ears. What condition should you be suspicious they have?

A

Neurofibromatosis type 2

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5
Q

If a child presents with nasal polyps what condition should you be thinking of

A

Cystic fibrosis

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6
Q

You suspect granulomatosis with polyangitis, what antibodies should you expect to find on bloods?

A

PR3 and cANCA

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7
Q

Where in thenose would you expect to find scheniderian papilloma subtype inverted and oncoytic ?

A

On the lateral walls and paranasal sinuses

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8
Q

Where in the nose would you expect to find scheniderian papilloma subtype exophytic ?

A

Septum

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9
Q

What groups of people commonly get scheniderian papillomas?

A

> 50 years

Solvent abusers
Smokers
Welders

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10
Q

What cancer is associated with exposure to the Epsteinbarr virus?

A

Nasopharyngeal carcinoma

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11
Q

What would you expect to find histologically with nasopharyngeal carcinoma?

A

Dysplasia of the epithelium to keratinising or non keratinising epithelium

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12
Q

Who is most likley to get laryngeal polyps?

A

Reactive change to laryngeal mucosa from;

SMOKING, SINGING, infection,

Associated with hypothyroidism

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13
Q

Squamous papilloma/ papillomatosis is associated with exposure to what virus?

A

HPV types 6-11

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14
Q

Squamous cell carcinoma is associated with exposure to what virus?

A

HPV 16

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15
Q

Male of 55yrs presents with a swelling around both his parotid gland. On histology there is a pink cytoplasm and the stroma has large lymphocyte invasion (b cells). He smokes. likely diagnosis

A

Warthins tumour

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16
Q

Name the two main malignant tumours found in the parotid gland

A

Adenoid cystic

Mucoepidermoid. Carcinoma

17
Q

What cell type lines the outer ear

A

Squamous epithelium with sebaceous and ceruminous glands

18
Q

What cell type lines the middle ear

A

Cuboidal epithelial cells

19
Q

What cell type lines the nasal vestibule and the rest of the lower nose

A

Stratified squamous epithelium

Pseudostratified ciliated columnar epithelium

20
Q

Name the cell types that line the throat

A

Oropharynx- stratified squamous epithelium

Everywhere else resp epithelium (pseudostratified squamous columnar epithelium