Pathology - Chem Path Flashcards
1
Q
What is the normal level of calcium?
A
2.2-2.6 mmol/l
2
Q
Which tissues make ALP?
A
Intestine, bone, liver, placenta
Most frequently pathologically high in liver or bone disease.
GGT can be used along side ALP to confirm liver damage over bone.
New testing cam also tell the difference between bone and liver isoenzymes.
3
Q
Physiological reasons for high ALP?
A
Pregnancy - 3rd trimester
Childhood - especially during a growth spurt
4
Q
What does a raised amylase suggest?
A
Acute pancreatitis (not chronic) - levels will be >10x the normal limit
Salivary glands also produce a different isoenzyme of amylase eg mumps
Acute abdomen problems can lead to small increases in amylase
5
Q
What are the 3 forms of creatine kinase?
A
CK - MM skeletal muscle
CK - MB cardiac muscle
CK - BB brain
