Pathology

Question 1

What sinonasal condition is associated with charcot leyden crystals?

Answer 1

Allergic fungal rhinosinusitis

Question 2

Macrophages in rhinoscleroma? What are eosinophilic round structures a/w plasma cells in rhinoscleroma called?

Answer 2

Mikulicz. Russel bodies

Question 3

“Soap bubble” cell in chordoma?

Answer 3

Physalliferous cells

Question 4

Nests of cells in paraganglioma?

Answer 4

Zellballen

Question 5

Mucor vs Aspergillus: septations? angle? background? shape?

Answer 5

Mucor = nonseptations, 90 degrees, tissue background, serpiginous. Aspergillus = +septations, 45 degrees, hyphae background, vermiform

Question 6

Path findings in rhinoscleroma vs rhinosporidiosis?

Answer 6

Rhinosclera has Mikulicz cells and Russell bodies. Rhinosporidium has pseudoepitheliomatous hyperplasia.

Question 7

Histological markers/genetic expression: low-grade mucoepidermoid carcinoma associated with what translocation?

Answer 7

t(11;19) translocation.

Question 8

histological markers in high grade mucoep a/w poor prognosis?

Answer 8

Ki67, Her2/neu

cribriform = swiss cheese and best prognosis. solid = worst prognosis. tubular = middle/low-grade.

Question 9

adenoid cystic associated with expression of what protein?

Answer 9

c-KIT

Question 10

what marker a/w acinic cell caricinoma?

Answer 10

Ki67

Question 11

Adenoid cystic - cribriform vs solid vs tubular: a) appearance b) prognosis

Answer 11

cribriform = swiss cheese and best prognosis. solid = worst prognosis. tubular = middle/low-grade.