Pathology Flashcards
where is a pituitary adenoma derived from?
anterior pituitary
what is a pituitary adenoma associated with?
MEN1
what can a large pituitary adenoma cause?
visual field defects
what can infarction of the pituitary cause?
panhypopituitarism
what disease is caused if the pituitary adenoma is ACTH secreting?
Cushing’s syndrome
what is craniopharyngioma derived from?
remnants of Rathke’s pouch
what is pituitary hypo function usually?
panhypopituitarism
causes of panhypopituitarism?
granulomatous inflammation (sarcoidosis)
infarction (Sheehan’s syndrome)
tumours
two examples of posterior pituitary syndromes
- diabetes insipidus
- SIADH secretion
causes of DI
trauma (surgery)
tumours
inflammatory disorders
two types of DI
central (ADH deficiency)
nephrogenic (renal resistance to ADH effects)
describe SIADH secretion
ectopic production of ADH (paraneoplastic syndrome)
