Cranial Diabetes Insipidus Flashcards
1
Q
define
A
this is a problem with ADH in the posterior pituitary/hypothalamus
2
Q
causes
A
familial
acquired
3
Q
familial causes
A
DIDMOAD DI DM optic atrophy deaf
4
Q
acquired causes
A
idiopathic tumour- more metastasis than primary tumour germinoma trauma inflammatory disorder e.g. sarcoidosis
5
Q
diagnosis
A
- water deprivation test (give desmopressin). should be Ur/serum osmol ratio >2, otherwise DI. if low and improves give desmopressin (DDAVP) then it is cranial not nephrogenic
- baseline urine to serum osmolality >2 avoids need for water deprivation test
6
Q
management
A
desmospray or desmopressin tablets or desmopressin injection (emergency)
