Pathology Flashcards

1
Q
genetic mutation of type V Collagen
def wich enzime
A
Ehlers-Danlos
procollagen peptidase (Cleavage of procollagen C- and N- chains)
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2
Q

Adolescent athlete

Knee pain worsen with Extension

A

Osgood-Schlatter Disease

Avulsion TIBIAL TUBERCULE (jumping)
Secondary ossification center

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3
Q

Paget disease of the Bone- Osteitis deformans
M-CSF & RANK-L – NFkB Osteoclast / mixed / osteoblast
Sx.
Rx
Tx

A

Sx: bone thickening and hearing loss
Rx: Osteosarcoma
Tx: bisphosphonates

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4
Q
Gradual onset of symptoms
Pleuritic
Fever
Arthralgias
Erythematous rash

ask for…

A

Anti-double strand DNA antibodies

High Specificity

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5
Q
high Osm
-
low ICF 
low ECF
cause?
A

Diabetes Insipidus
high serum osmolarity
low urine osmolarity

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6
Q

ANTICARDIOLIPIN…
LUPUS ANTICOAGULANT…
produce?

A

Antiphospholipid Syndrome
Anticardiolipin__ FALSE + VDRL/RPR
Lupus Anticoagulant__ kPTT prolonged (but)

HYPERCOAGULABILITY STATE
#Thrombosis
#Preganancy Loss-Abortion
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