Dermatology

Question 1

SUN UV
DNA Pyridine dimers…
- Repair by Nucleotide Excision Repair
DNA polymerase in G1..

this is defective in…

Answer 1

Xeroderma Pigmentosum

“photosensitivity and Skin cancer in young”

Question 2

Intensely pruritic on the flexor surface of the wrist, lateral surface of the finger, and finger webs
WORSE AT NIGTH

Answer 2

Sarcoptes scabei

• Permethrin and wash clothes

Question 3

erythematous hyperkeratosis covered by silver scale
Pinpoint bleeding (sign?)
mildly pruritic
Koebner phenomenon
parakeratosis and cubed rete ridges

Answer 3

Psoriasis
–Auspitz sign!

+ stratum spinosum
- stratum granulosum

Question 4

IgG ab DESMOSOMES (desmoglein 1-3)
Flaccid bullae
ORAL MUCOSA affected
- new blisters form w/gentle traction
- bullae spread laterally when applied pressure
IF ¿?

Answer 4

Nikolsky +
Asboe-Hansen sign +

IF: RETICULAR

Question 5

IgG ab HEMIDESMOSOMES
TENSE blisters
NO oral compromise

IF?

Answer 5

Bullous Pemphigoid

IF: LINEAR

Question 6

+ common skin cancer
sun-exposed
waxy pink pearly nodules - nonhealing ulcers
-· Palisading of Nuclei

Answer 6

Basal Cell carcinoma

Question 7

premalignant lesions by sun expousure
Small, ROUGH, papules or plaques w/scale
hyperkeratosis & parakeratosis & Keratinocite atipia
– RISK ok SQUAMOUS CELL CARCINOMA

Answer 7

Actinic Keratosis

Question 8

6P
INFILTRATE OF LYMPHOCYTES at the dermal-epidermal junction
Thickened of stratus GRANULSOSUS with sawtooth rate ridges
Wickham Striae- reticular withe lines
associated with hepatitis C

Answer 8

Priritic, Purple/Pink, Polygonal, Planar Papules and Plaques

LICHEN PLANUS

Question 9

flat greasy pigmented
Looks “Stuck on” & waxy
Horn cyst - microscope: keratin containing cyst

Rapid onset…

Answer 9

SEBORRHEIC KERATOSIS

Rapid onset… LASER-TRELAT sign: malignancy (GI)

Question 10

Skin: ·Target Lesions·
ass. w/ Herpes, mycoplasma, and Sulfas
T-cells

Answer 10

Erythema Multiforme

Question 11

INTENSE PRURITIC eruption
associated w/asthma & allergic
mutation in the filaggrin gene (skin barrier dysfunction)
face on infants or antecubital fosa
High IgE / eosinophilia

Answer 11

Atopic Dermatitis

ECZEMA

Question 12

Depigmentation
Absence of Melanocytes
associated with other autoimmune

Answer 12

VITILIGO

Question 13

Most common benign vascular tumor in children?

strawberry-like bright red compressible plaques

Answer 13

Capillary hemangioma

Question 14

Acanthosis nigricans
associated w/
-
-

Answer 14

Insulin resistance (DBT, obesity, Cushing, PCOS)
Visceral malignancy (gastric adenocarcinoma)

Question 15

Type IV Hypersensitivity
erythematous papulovesicular weeping lesions
SPONGIOSIS & EDEMA FLUID

Answer 15

ALLERGIC CONTACT DERMATITIS

Question 16

Chronic lymphedema risk of developing…

Answer 16

Cutaneous Angiosarcoma

Steward-Treves Sindome

Question 17

Cutibacterium acnes colonize …

Answer 17

Pilosebaseous follicles

anaerobic lipid-rich environment

Question 18

defective keratinocyte desquamation
sry scaly skin
loss of normal barrier function
mutation in the filaggrin gene
Symptoms worsen with age and winter (less humidity)

Answer 18

Ichthyosis Vulgaris

Question 19

ROUGH skin lesion in sun exposure

+ RISK of SCC

Answer 19

ACTINIC KERATOSIS

Question 20

hyperkeratosis
parakeratosis
Epidermal hyperplasia
Acanthosis with CLUBBED RETE REGED

Answer 20

PSORIASIS

Silver scaling
+SPINOSUM

Question 21

microorganism

NON- purulent cellulitis:
Purulent Cellulitis:

Answer 21

NON-purulent cellulitis: Strepto Grup A

Purulent cellulitis: Staphilococus aureus