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Phase 2 > PATHOLOGY > Flashcards

PATHOLOGY Flashcards

1
Q

Define healing and repair

A

Healing is when tissue damage resolves with minimal or no residual damage (eg skin abrasion). (no tissue loss - healing by first intention(
Repair is when there is tissue loss and organisation has to happen to fill in the gap of the lost tissue - healing by second intention. After repair there is regeneration of liable cells (eg hepatocytes etc) but architecture cannot be regenerated.

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2
Q

What is granulation tissue

A

Loops of capillaries and myofibroblasts (secrete collagen + matrix)
Part of organisation, which is a repair process when there is tissue loss

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3
Q

What tissues cannot regenerate

A

Cardiac and smooth muscle cannot regenerate
Skeletal muscle has some regeneration but not much
Neurons

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4
Q

What is RAS

A

onco-gene - regulates cell proliferation

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5
Q

What is APC associated with

A

Familial adenomatous polyposis

100% penetrance

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Phase 2 (12 decks)

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