Pathology Flashcards
Fordyce Granules What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Ectopic sebaceous glands in the oral cavity
most common on buccal mucosa and upper lip
many yellow plaques or granules
No treatment
Leukoedema What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Intracellular edema of cells White, foggy bilateral buccal mucosa white areas dissapear with stretching No treatment
Varices What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Dilated blood vessels
blue veins that bulge
Lip and under the tongue
No treatment
Geographic Tongue (Erythema Migrans) What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Atrophy of filliform papillae with keratinized border
Red, Flat cental area with white serpentine border
typically on tongue, can be anywhere in oral cavity
It moves around
no treatment, unless symptomatic = corticosteroid
Tori What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Abnormal bone growth
pink, hard growth of bone covered by healthy epithelium
hard palate and lingual surface of mandible by premolars
no treatment unless growth is excessive or required for prosthesis
Physiologic pigmentation What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Pigmentation of intra oral tissues
typically seen in darker individuals
Ankyloglossa
tongue tied
short lingual frenum
Cleft lip and palate
Defect between median nasal process and maxillary process (lip)
defect between palatal shelves (palate)
Radiographic radiolucencies that extend from the nasal cavity to the oral cavity
Morsicatio What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Chronic Mucosa Chewing White rough tissue above and below lingual planes Must be in a location that the patient can chew No treatment
White Sponge Nevus What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
autosomal dominant mutation causing keratin production
Thick White folds of velvety tissue
Multifocal (buccal mucosa, ventral tongue, soft palate…)
No treatment
LInea alba
Hyperkeratosis line on the buccal mucosa at the height of the occlusal table
no treatment
Oral Hairy Leukoplakia What causes it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Epstein barr white rough plaque lateral border of the tongue seen in immune compromised patients no treatment (sign of immunocompromised state)
Hairy Tongue What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Elongation of filliform papillae
looks like a hairy tongue
dorsal surface of the tongue
Treatment = Scrape tongue
Reticular Lichen Planus What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
autoimmune disorder
Oral cavity = White lacy pattern, doesn’t rub off
Multifocal
Wickhams Striae, purple, pruritic papules on skin
no treatment unless burning = corticosteroids
Erosive Lichen Planus What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
autoimmune disorder with painful ulcerations
Painful ulcerations, pseudomembrane with erythema
Multifocal
remnants of Wickhams Striae, purple, pruritic papules on skin
treatment = topical steroids (severe = systemic corticoids)
Nicotinic Stomatitis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
heat of smoking causes minor salivary glands of the hard palate to become inflamed
red gland ducts with white leukoplakic background
on the palate
no treatment (not premalignant)
White Candidosis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
opportunistic growth of candida albicans
pseudomembranous white patches that rub off leaving red base, painful
Generalized
pts are immunocompromised, taking antibiotics or corticosteroids
Treatment = antifungal medication
which is more common
reticular or erosive lichen planus
reticular
Acute Erythematous Candidosis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
opportunistic growth of candida albicans painful and burning erythema generalized typically follows broad spectrum antibiotics (antibiotic sore mouth) treatment = antifungal medication
Chronic Erythematous Candidosis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Candida growth in denture bearing area
potentially painful erythematous area
only on denture bearing areas
may be caused by things other than candida (bad denture hygeine, poorly fitting dentures)
treatment = improve dentures/care/antifungal
Angular Chelitis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Candida and Bacterial infection Erythematous lesions Oral commisures often associated with VDO loss Treatment = antifungal and antibiotic
Median Rhomboid Glossitis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Candida infection
erythematous rhomboid patch
midline on dorsal surface of tongue
“kissing lesion” on palate
Chemical/Physical Burn
What is it?
What is it’s appearance?
burn causing necrosis of epithelial tissue
white pseudomembranous patch that rubs off with difficulty
Scarlet Fever
what is it
oral manifestation
Group A strep infection Strawberry tongue (white coating with red dots that transitions to red coating with white dots)
Hemangioma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Tumor of Vasculature
red/purple tumor
located anywhwere
Blanches, not present at birth, rapidly growing
Treament = none, gradual involution (goes away)
Venous Malformation What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Abnomalities without endothelial proliferation red/purple growth located anywhere Blanches, present at birth no treatment, but doesn't go away
Sturge weber angiomatosis
Port wine stain (venous malformation)
Petechiae What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Submucosal hemorrhage from minor trauma very small red/purple bruises hard palate, buccal mucosa, can be anywhere doesn't blanch no treatment
Ecchymosis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Submucosal hemorrhage from minor trauma red/purple bruises larger than 2 cm can be anywhere doesn't blanch no treatment
Hematoma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Submucosal hemorrhage from trauma red/purple mass caused by accumulated blood can be anywhere doesn't blanch no treatment
Kaposi's Sarcoma What causes it? What is it's appearance? Where is it typically located? Key identifiers?
caused by HHV-8 red/purple tumor located anywhere in oral cavity and on the body malignant seen in immunocompromised patients
Aquired Melanocytic Nevus (mole) What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
controlled proliferation of melanocytes
small blue/brown macule
can be anywhere
Treatment = biopsy
Malignant Melanoma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Uncontrolled proliferation of melanocytes
may begin as blue/brown macule, becomes raised more widespread
can be located anywhere
ABCDE
oral melanoma has very poor prognosis
Heavy metal intoxication What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
inclusion of heavy metals into oral tissues
blue-gray line along gingival margin
gingival margin
burtons line (history of working with heavy metals)
no treatment
traumatic Ulcer What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Ulcer caused by mechanical trauma
red center lesion with white keratin border
located near a source of irritation
Treatment = remove source of irritation
(if no source of irritation can be found or lesion persists following removal of irritation it needs to be biopsied)
Aphtous Stomatitis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
ulcerations of unknown cause
central white area with surrounding red halo
ONLY on NON-KERATINIZED tissue
Treatment = corticosteroids
Primary Herpes Simplex What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Initial infection with HSV 1 (2)
small vesicles that rupture and coalesce to form large ulcerations
BOTH keratinized and non keratinized tissues
typically presents with fever, malaise, lymphadenopathy
Treatment = acyclovir (within first 3 days)
Recurrent Herpes Simplex What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Flaring up of existing HSV 1(2) infection
small vesicles that rupture and coalesce to form large ulcerations
ONLY KERATINIZED TISSUES
doesn’t present with fever/malaise. has prodrome
Treatment = Valacyclovir
Herpes Zoster What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
HHV-3 infection
small vesicles that rupture and coalesce to form large ulcerations
intraorally and extra oral
follows a dermatome
Pemphigus Vulgaris What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Autoimmune disease that attacks desmosomes
Ulcerations of skin/mucosa
generalized, intra and extra oral
intraepithelial splitting, nikolsky sign, immunofluoresence, long duration
Treatment = corticosteroids
Mucous Membrane Pemphigoid What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Autoimmune disease that hemidesmosomes Ulcerations of skin/mucosa generalized intra and extra oral subepithelial splitting, eye involvement, symblepharon, immunofluresence, long duration treatment = corticosteroids
Systemic Lupus Erythematosus What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Multisystem Autoimmune disease Ulcerations generalized lesions butterfly rash, long duration treatment = corticosteroids
Chronic Cuatneous Lupus Erythematosus
like SLE but only has skin and oral lesions
Erythema multiforme What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Generalized Ulcerative condition of unknown etiology
Generalize ulcerations
Generalized
Sometimes preceeded by herpes, pneumonia, or medications, FAST onset, target lesions, BLACK CRUSTY LIPS
treatment = self resolving, corticosteroids prn
Chron's disease What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
inflammatory bowel disease
oral = labial swelling, apthous ulcers, mucosal tags, granulomatous gingiva
from anus to oral cavity
cobblestoning of GI tract
treatment = steroids/immunosuppressants (doesn’t cure)
Epilus fissuratum What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
hyperplastic fibrous connective tissue
sheet of fibrous CT
buccal vestibule
Associated with overextended denture flange
Treatment = excision if necessary, adjust denture flange
Inflammatory papillary hyperplasia What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
hyperplastic fibrous tissue papillary projections denture bearing areas (palate) caused by poor fitting dentures/24 hour wear treatment = better denture care
Denture leaf fibroma
leaf like fibroma on hard palate under a denture
Papilloma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Benign Warty projection of Squamous epithelium associated with HPV
rough surface with multiple finger like projections with pedunculated base
Verruca Vulgaris What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Benign Warty projection of Squamous epithelium associated with HPV
rough surface with multiple finger like projections with sessile base
single lesions
more common on skin
Condyloma
papilloma like growths, typically multiple and associated with high risk HPVs
What are the 5 P’s of gum bumps
parulis plain fibroma pyogenic granuloma peripheral ossifying fibroma peripheral giant cell granuloma
Parulis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Gum bump formed from pus caused by infection of necrotic tooth canal that accumulated under epithelium
mass on the gums
gingiva
found near a necrotic tooth, doesn’t blanch, pus filled
Treatment = treat source of infection
Peripheral ossifying fibroma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Overgrowth of fibrous tissue
Red or pink growth
Gingiva
doesn’t blanch
Peripheral Giant Cell granuloma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Overgrowth of vascular tissue
Red/purple growth
gingiva
blanches
Pyogenic granuloma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Overgrowth of vascular tissue
red/purple growth
gingiva
blanches, common in pregnancy
Plain Fibroma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
overgrowth of fibrous tissue
firm pink growth
can be found anywhere
Doesn’t blanch
Do salivary lesions ever occur on attached gingiva
nope
What is the only tumor of neural origin that hurts
traumatic neuroma
What is the most common site of a Granular Cell tumor
dorsum of tongue
What are the tumors of muscle origin
leiomyoma (smooth muscle tumor) anywhere
Rhabdomyoma (skeletal muscle) not on palate or gingiva
What is the tumor of fat origin
lipoma (anywhere)
Congenital Epilus
Bump on the alveolar ridge that is present at birth
Lymphoepithelial cyst
What is it?
What is it’s appearance?
Where is it typically located?
Cyst of lymphatic tissue
well circumscribed pale/yellow swelling
found in waldeyers ring (floor of mouth, tonsillar pillar, lateral tongue)
Lymphangioma What is it? What is it's appearance? Where is it typically located? Key identifiers?
lymph filled superficial vessels
many red/yellow bumps
most commonly on dorsum of tongue
Frog-egg appearance
Leukemia
What is it?
What does it cause?
Excessive production of Abnormal WBCs in bone marrow
decrased RBCs = fatigue, shortness of breath
decreased functioning WBCs = increased infections
decreased platelets = prolonged bleeding
Oral manifestations of leukemia
petechia a purpura
spontaneous and prolonged gingival bleeding
boggy gingival enlargement and ulcerations
candidosis
herpes and apthous can happen anywhere
What tests to order when suspecting leukemia
complete blood count
white blood count differntial
Langerhans Cell disease
What is it?
What is it’s radiographic appearance?
proliferation of langerhans cells for unknown reasons
Scooped out bone, teeth floating in air
Multiple Myeloma
What is it?
What is it’sradiographic appearance?
Key identifiers?
multifocal malignancy of plasma cells
multiple punched out lesions (well defined)
Bence Jones Proteins
Cheilitis Glandularis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
inflammation of minor salivary glands
swelling of lip with inflammed ducts
typically on lower lip
risk of squamous cell carcinoma
Necrotizing Sailometaplasia What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Necrotic Ulceration of tissue due to local ischemia
Necrotic ulceration, exposing bone (makes a hole)
Posterior hard palate near GP foramen
Rapid onset, often follows local anesthesia (GP block)
Treatment = mimics squamous cell carcinoma, should be biopsied, self resolving
Mucocele What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Severed salivary duct leading to mucous accumulation under the epithelium often caused by trauma
bluish dome shaped vesicle
typically on the lower lip, can be anywhere there are salivary glands
history of recurrence
treatment = none, unless large and frequently recurring then excision
Ranula
Mucocele found on the floor of the mouth
looks like frog belly
Danger of plunging ranula (mucous retention spreading into fascial spaces that can asphyxiate the patient)
Most common salivary gland tumor
pleomorphic adenoma
most common benign salivary gland tumor
pleomorphic adenoma
most common malignant salivary gland tumor
mucoepidermoid carcinoma
most common location for salivary gland tumors
parotid gland
Pleomorphic adenoma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
benign salivary gland tumor
swelling under epithelium
common in parotid gland but can occur anywhere
treatment = incisional biopsy, excision
Mucoepidermoid carcinoma
most common malignant salivary gland tumor
Canalicular Adenoma
Salivary gland tumor commonly found on the upper lip
Warthin's tumor What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
(papillary cystic lympomatosum)
benign tumor
almost always in the parotid, can be bilateral
associated with smoking
Sjogren's Syndrome What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Autoimmune disease that attacks the salivary glands and lacrimal glands
Bilateral swelling of parotid glands
parotid glands, lacrimal glands
Xerostomia and Xeropthalmia
Secondary Sjogren’s includes a second autoimmune disease
Leukoplakia
White patch that does not rub off
term only used when the white lesion cant be anything else
what are the 4 things leukoplakia could be
hyperkeratosis (95%)
dysplasia
carcinoma in situ
squamous cell carcinoma
what is erythroplakia
red patch that doesn’t rub off
much more commonly dysplasia or SCC than leukoplakia
Actinic Chelitis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Premalignant change of lower lip vermillion
causes atrophy of vermillion border
lower lip
due to excessive exposure to UV, 6-10% of cases are cancer
Squamous Cell Carcinoma What is it? What is it's appearance? Where is it typically located? contributing factors? Treatment?
most common intra-oral cancer
Many forms, non-healing ulcer, red or white patch, mass
most common on lateral border of the tongue and floor of the mouth
smoking, drinking, HPV, genetic effects
Verroucus Carcinoma What is it? What is it's appearance? Where is it typically located? Key identifiers?
Low grade form of squamous cell carcinoma
slow growing warty, rough, white surface
found anywhere
low tendancy to metastisize
Basal Cell carcinoma What is it? What is it's appearance? Where is it typically located? Key identifiers?
Painless ulcer on sun exposed face
Raised rolled border with central depression or ulceration
above the lip tragus line, never in mouth
doesn’t typically metastisize
telangiectasia
Alveolar Osteitis
What is it?
Treatment?
Dry socket, Exposed bone following EXT
radiograph to rule out root tip or foreign body, irrigate with warm saline, don’t curretage, analgesics
Rarefying Osteitis What is it? What is it's appearance? Where is it typically located? different types? Treatment?
The destruction of bone around the apex of a non-vital tooth
radiolucency around apex of tooth
radicular cyst, granuloma, abscess
Endo/EXT
Condensing Osteitis
What is it?
What is it’s appearance?
Treatment?
A sclerotic band of bone surrounding rarefying osteitis
RO border around RL lesion at apex of necrotic tooth
Endo/EXT
Idiopathic Osteosclerosis What is it? What is it's appearance? Key identifiers? Treatment?
non-inflammatory portion of more dense bone
radiopaque area that blends with the trabeculae
not fused to root or associated with RL lesion
no treatment needed
Chronic Osteomyelitis What is it? What is it's appearance? Where is it typically located? Key identifiers?
Acute/Chronic bone inflammation away from the initial site caused by staph/strep
Large diffuse, not well defined area of “MOTH EATEN” bone
pain is common
Osteomyelitis with proliferative periostitis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
inflammation of the bone spreading to the periosteum
periostium lifts and deposits bone creating onion skin appearance
commonly found in young people, on mandible
What is the most common developmental cyst
dentigerous cyst
Dentigerous cyst What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
expansion of the follicle around an unerupted tooth
radiolucency around the crown of a tooth attached to CEJ
most common on unerupted 3rd molars and max canines
RL area around crown of tooth (must be at least 2mm to be pathologic)
may transform into ameloblastoma or SCC
Lateral Periodontal Cyst
true odontogenic cyst forms lateral to the root of a tooth
typically in premolar canine area
Odontogenic Keratocyst What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
odontogenic Cyst with high recurrence rate
mimics anything, unilocular/multilocular, apical, lateral, small or large
only in odontogenic areas
Associated with Gorlin Syndrome
Treatment = enucleation, curretage, rinse of some sort
Calcifying Odontogenic Cyst
What is it?
What is it’s appearance?
Key identifiers?
Only cyst that can be mixed RL/RO (odontogenic tumors may be mixed)
Histologic Ghost Cells
Ameloblastoma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Most common true odontogenic tumor
radiolucency with soap bubble appearance, may be unilocular
common in 24-40 year olds, most common in posterior mandible
causes expansion
Ameloblastic Fibroma/ Ameloblastic Fibro-odontoma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
odontogenic tumor precursor to odontoma
AF = completely RL, AFO = mixed RL/RO
typically in the posterior mandible of <20 year olds
Odontoma
What is it?
What is it’s appearance?
What types?
Tumor of tooth tissues
Radiopaque area, radiolucent rim, surrounded by RO line
Compound = toothlets (anterior Max)
Complex = large unidentifiable mass (posterior mandible)
Adenomatoid Odontogenic Tumor
What is it?
Key identifiers?
Radiographic Appearance?
2/3 tumor 2/3 teens 2/3 females 2/3 anterior jaw 2/3 maxilla may be RL or mixed mixed has snowflake calcifications
Odontogenic Myxoma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
benign odontogenic tumor of connective tissue
appears with honeycomb or tennis racket appearance (septations at 90 degrees)
found in younger patients <30
Nasopalatine Duct Cyst What is it? What is it's appearance? Where is it typically located? Key Identifiers?
Non-odontogenic cyst in the incisive canal
may have palatal swelling, heart shaped RL lesion at max midline
Heart Shaped RL lesions at max midline
What is the most common non-odontogenic developmental cyst
Nasopalatine Duct Cyst (incisive canal cyst)
Nasolabial Cyst What is it? What is it's appearance? Where is it typically located? Key identifiers?
Soft tissue Cyst, not in bone
smooth swelling adjacent to max lat incisor
causes elevation of ala
no radiographic changes
Idiopathic Bone Cavity What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
simple bone cyst, traumatic bone cyst (it is an empty cavity in the bone) unknown cause
RL lesion with interdental scalloping
usually in mandibular premolar area
treatment = opening cavity = spontaneous healing
Mucous Retention pseudocyst What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
accumulation of mucus under the lining of the sinus
dome shaped RO lesion in the sinus, non-corticated
max sinus
no treatment necessary
Stafne Defect What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Depression in the mandible caused by submandibular salivary gland
RL lesion with thick corticated superior border
Below IAC usually at the angle of mandible
No treatment
Osteoma What is it? What is it's appearance? Key identifiers? Treatment?
Benign tumor of bone
Irregularly shaped radioopaque mass
multiple Osteomas associated with Garner’s syndrome
What is osteoma cutis
osteomas in skin/buccal mucosa
multiple _______’s are associated with Garners Syndrome
osteomas
What are the Giant Cell Lesions
Central giant Cell granuloma
Hyperparathydroidism
Cherubism
Central Giant Cell Granuloma What is it? What is it's appearance? Where is it typically located? Key identifiers?
Giant Cell tumor
Soap bubble appearance and expansion (resembles ameloblastoma) commonly causes root resorption
Typically found in females <30 in anterior mandible
Cherubism What is it? What is it's appearance? Where is it typically located? Key identifiers?
Multilocular radiolucent lesions in the jaws
bilateral, multilocular, expansile lesions in the jaw
begins between 1-4 years old
BILATERAL, expansile lesions
Hyperparathyroidism What is it? Radiographic appearance? Where is it typically located? Key identifiers? Treatment?
Parathyroid gland hyperfunction
granular, salt and pepper, ground glass bone
loss of lamina dura
painful bones, renal stones, abdominal groans, psychotic moans
Focal Cemento-Osseous Dsyplasia
What is it?
radiographic appearance?
Where is it typically located?
dysplasia, typically asymptomatic
RL or Mixed lesion (rarely RO)
Single lesion, not in anterior mandible
no treatment necessary
Periapical Cemento-Osseous Dsyplasia
What is it?
radiographic appearance?
Where is it typically located?
dysplasia, typically asymptomatic
RL or Mixed lesion (rarely RO)
involves mandibular anterior teeth
no treatment necessary
Florid Cemento-Osseous Dsyplasia
What is it?
radiographic appearance?
Where is it typically located?
dysplasia, typically asymptomatic
RL or Mixed lesion (rarely RO)
involves multiple quadrants
Fibrous Dysplasia What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
painless unilateral Swelling of the jaw of genetic cause
ground glass appearance of bone, causing expansion
early onset, stops at age 20
Treatment = cosmetic bone after growth cessation
Paget's disease of bone What is it? radiographic appearance? Where is it typically located? Key identifiers? Treatment?
abnormal resorption and deposition of bone causing weakened deformed bone cotton wool appearance of bone excessive hypercementosis enlargement of jaws increased risk of osteosarcoma occurs in >40 year olds
Melanotic Neuroectodermal tumor of infancy What is it? What is it's appearance? Where is it typically located? Key identifiers?
tumor with rapid onset
Radiolucency in anterior maxilla
increase in VMA
destructive tumor
Osteopetrosis
What is it?
What is it’s appearance?
Where is it typically located?
Defect in osteoclasts causing increased bone density and osteomyelitis
can cause cranial nerve compression and bone fractures
Neurofibroma/Schwannoma What is it? What is it's appearance? Where is it typically located? what to look out for? Treatment?
Tumor of nerve tissue or schwann cells
causes enlargement of canals and/or foramina
Look out for hemangioma
always aspirate before biopsy to rule out vascular in nature
Most common primary bone cancer
osteosarcoma
Most common cancer in bone
Metastisized lesions
what is the numb chin syndrome
parasthesia of lower lip often caused by malignancies
Osteosarcoma What is it? radiographic appearance? Where is it typically located? Key identifiers?
Malignant connective tissue lesions
poorly defined, sun-ray appearance, irregular widening of PDL space
causes swelling of bone, loose teeth, paresthesia
Cleidocranial dysplasia
Radiographic/clinical findings
multiple unerupted supernumerary teeth
hypoplasia/aplasia of clavicle
Ectodermal dysplasia
Radiographic/clinical findings
hypodontia, conical shaped teeth
fine sparse hair, decreased heat tolerance
Multiple endocrine neoplasia
Radiographic/clinical findings
oral mucosal neuromas
medullary carcinoma of thyroid
pheochromocytoma of adrenal gland
Neurofibromatosis
Radiographic/clinical findings
multiple neurofibromas
cafe au lait spots
axillary freckling
lisch nodules
Peutz Jegher syndrome
Radiographic/clinical findings
numerous melanotic macules
intestinal polyps
Gardner syndrome
Radiographic/clinical findings
Osteomas that may block eruption
polyps that become malignant
epidermoid cysts on skin
Treacher Collins syndrome (mandibulofacial dysostosis)
Radiographic/clinical findings
Deformed ears/hearing loss
Coloboma - lower eyelid fissure
convex profile, Bird face
Gorlin Syndrome (nevoid basal cell carcinoma syndrome) Radiographic/clinical findings
Multiple basal cell carcinomas Odontogenic Keratocysts Calcified falx cerebri rib anomalies palmar plantar pits ocular hypertelorism enlarged head spina bifida
Hypercementosis
Radiographic findings
too much cementum, regular PDL space
(generalized hypercementosis = paget’s disease
Cementoblastoma
Radiographic findings
large mass of cementum with radiolucent rim around it, causing root resorption
Ankylosis
tooth fused to bone, shortened root, no PDL space
Dens Evaginatus
cusp like elevation of enamel
most common on mandibular premolars
Dens Invaginatus
tooth in tooth
most common on max laterals
Attrition
wear from tooth to tooth contact
abrasion
pathologic wear from an external agent
Erosion
pathologic wear due to chemicals
perimolysis = erosion from gastric regurgitation
Abfraction
loss of tooth structure from flexion and failure of enamel/dentin caused by occlusion
hypoplastic Amelogenesis Imperfecta
not enough enamel, rough and pitted enamel
hypocalcified amelogenesis imperfecta
regular thickness that is soft and easily breaks off
hypomature amelogenesis imperfecta
regular thickness, soft, “snow capped”
What disease causes picket fence look of teeth
amelogenesis imperfecta
Dentinogenesis imperfecta
teeth are translucent (blue to brown) bulbous crowns, cervical constriction thin tapered roots obliteration of root canals and pulp chamber "Golf ball on a tee"
Osteogenesis imperfecta
what is it?
what are the clinical signs?
Genetic disease that leads to defective collagen
opalescent teeth, brittle bones and fractures
blue sclera, bowing of legs
blue brown discoloration of teeth
Type 1 Dentin Dysplasia
Developmental defect of dentin radicular type rootless teeth pulpal obliteration tooth mobility
Type 2 dentin dysplasia
developmental defect of dentin
coronal type
enlarged thistle tube shaped pulp chambers
Progressive Systemic Sclerosis
what is it?
Oral symptoms
autoimmune disease causing hardening of the skin
Trismus, generalized widening of PDL space
Condylar hyperplasia
what is it? symptoms?
enlarged condyle
causes deviation away from affected side