Pathology Flashcards
Fordyce Granules What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Ectopic sebaceous glands in the oral cavity
most common on buccal mucosa and upper lip
many yellow plaques or granules
No treatment
Leukoedema What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Intracellular edema of cells White, foggy bilateral buccal mucosa white areas dissapear with stretching No treatment
Varices What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Dilated blood vessels
blue veins that bulge
Lip and under the tongue
No treatment
Geographic Tongue (Erythema Migrans) What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Atrophy of filliform papillae with keratinized border
Red, Flat cental area with white serpentine border
typically on tongue, can be anywhere in oral cavity
It moves around
no treatment, unless symptomatic = corticosteroid
Tori What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Abnormal bone growth
pink, hard growth of bone covered by healthy epithelium
hard palate and lingual surface of mandible by premolars
no treatment unless growth is excessive or required for prosthesis
Physiologic pigmentation What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Pigmentation of intra oral tissues
typically seen in darker individuals
Ankyloglossa
tongue tied
short lingual frenum
Cleft lip and palate
Defect between median nasal process and maxillary process (lip)
defect between palatal shelves (palate)
Radiographic radiolucencies that extend from the nasal cavity to the oral cavity
Morsicatio What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Chronic Mucosa Chewing White rough tissue above and below lingual planes Must be in a location that the patient can chew No treatment
White Sponge Nevus What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
autosomal dominant mutation causing keratin production
Thick White folds of velvety tissue
Multifocal (buccal mucosa, ventral tongue, soft palate…)
No treatment
LInea alba
Hyperkeratosis line on the buccal mucosa at the height of the occlusal table
no treatment
Oral Hairy Leukoplakia What causes it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Epstein barr white rough plaque lateral border of the tongue seen in immune compromised patients no treatment (sign of immunocompromised state)
Hairy Tongue What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Elongation of filliform papillae
looks like a hairy tongue
dorsal surface of the tongue
Treatment = Scrape tongue
Reticular Lichen Planus What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
autoimmune disorder
Oral cavity = White lacy pattern, doesn’t rub off
Multifocal
Wickhams Striae, purple, pruritic papules on skin
no treatment unless burning = corticosteroids
Erosive Lichen Planus What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
autoimmune disorder with painful ulcerations
Painful ulcerations, pseudomembrane with erythema
Multifocal
remnants of Wickhams Striae, purple, pruritic papules on skin
treatment = topical steroids (severe = systemic corticoids)
Nicotinic Stomatitis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
heat of smoking causes minor salivary glands of the hard palate to become inflamed
red gland ducts with white leukoplakic background
on the palate
no treatment (not premalignant)
White Candidosis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
opportunistic growth of candida albicans
pseudomembranous white patches that rub off leaving red base, painful
Generalized
pts are immunocompromised, taking antibiotics or corticosteroids
Treatment = antifungal medication
which is more common
reticular or erosive lichen planus
reticular
Acute Erythematous Candidosis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
opportunistic growth of candida albicans painful and burning erythema generalized typically follows broad spectrum antibiotics (antibiotic sore mouth) treatment = antifungal medication
Chronic Erythematous Candidosis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Candida growth in denture bearing area
potentially painful erythematous area
only on denture bearing areas
may be caused by things other than candida (bad denture hygeine, poorly fitting dentures)
treatment = improve dentures/care/antifungal
Angular Chelitis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Candida and Bacterial infection Erythematous lesions Oral commisures often associated with VDO loss Treatment = antifungal and antibiotic
Median Rhomboid Glossitis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Candida infection
erythematous rhomboid patch
midline on dorsal surface of tongue
“kissing lesion” on palate
Chemical/Physical Burn
What is it?
What is it’s appearance?
burn causing necrosis of epithelial tissue
white pseudomembranous patch that rubs off with difficulty
Scarlet Fever
what is it
oral manifestation
Group A strep infection Strawberry tongue (white coating with red dots that transitions to red coating with white dots)
Hemangioma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Tumor of Vasculature
red/purple tumor
located anywhwere
Blanches, not present at birth, rapidly growing
Treament = none, gradual involution (goes away)
Venous Malformation What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Abnomalities without endothelial proliferation red/purple growth located anywhere Blanches, present at birth no treatment, but doesn't go away
Sturge weber angiomatosis
Port wine stain (venous malformation)
Petechiae What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Submucosal hemorrhage from minor trauma very small red/purple bruises hard palate, buccal mucosa, can be anywhere doesn't blanch no treatment
Ecchymosis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Submucosal hemorrhage from minor trauma red/purple bruises larger than 2 cm can be anywhere doesn't blanch no treatment
Hematoma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Submucosal hemorrhage from trauma red/purple mass caused by accumulated blood can be anywhere doesn't blanch no treatment
Kaposi's Sarcoma What causes it? What is it's appearance? Where is it typically located? Key identifiers?
caused by HHV-8 red/purple tumor located anywhere in oral cavity and on the body malignant seen in immunocompromised patients
Aquired Melanocytic Nevus (mole) What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
controlled proliferation of melanocytes
small blue/brown macule
can be anywhere
Treatment = biopsy
Malignant Melanoma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Uncontrolled proliferation of melanocytes
may begin as blue/brown macule, becomes raised more widespread
can be located anywhere
ABCDE
oral melanoma has very poor prognosis
Heavy metal intoxication What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
inclusion of heavy metals into oral tissues
blue-gray line along gingival margin
gingival margin
burtons line (history of working with heavy metals)
no treatment
traumatic Ulcer What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Ulcer caused by mechanical trauma
red center lesion with white keratin border
located near a source of irritation
Treatment = remove source of irritation
(if no source of irritation can be found or lesion persists following removal of irritation it needs to be biopsied)
Aphtous Stomatitis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
ulcerations of unknown cause
central white area with surrounding red halo
ONLY on NON-KERATINIZED tissue
Treatment = corticosteroids
Primary Herpes Simplex What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Initial infection with HSV 1 (2)
small vesicles that rupture and coalesce to form large ulcerations
BOTH keratinized and non keratinized tissues
typically presents with fever, malaise, lymphadenopathy
Treatment = acyclovir (within first 3 days)
Recurrent Herpes Simplex What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Flaring up of existing HSV 1(2) infection
small vesicles that rupture and coalesce to form large ulcerations
ONLY KERATINIZED TISSUES
doesn’t present with fever/malaise. has prodrome
Treatment = Valacyclovir
Herpes Zoster What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
HHV-3 infection
small vesicles that rupture and coalesce to form large ulcerations
intraorally and extra oral
follows a dermatome
Pemphigus Vulgaris What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Autoimmune disease that attacks desmosomes
Ulcerations of skin/mucosa
generalized, intra and extra oral
intraepithelial splitting, nikolsky sign, immunofluoresence, long duration
Treatment = corticosteroids
Mucous Membrane Pemphigoid What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Autoimmune disease that hemidesmosomes Ulcerations of skin/mucosa generalized intra and extra oral subepithelial splitting, eye involvement, symblepharon, immunofluresence, long duration treatment = corticosteroids
Systemic Lupus Erythematosus What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Multisystem Autoimmune disease Ulcerations generalized lesions butterfly rash, long duration treatment = corticosteroids
Chronic Cuatneous Lupus Erythematosus
like SLE but only has skin and oral lesions
Erythema multiforme What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Generalized Ulcerative condition of unknown etiology
Generalize ulcerations
Generalized
Sometimes preceeded by herpes, pneumonia, or medications, FAST onset, target lesions, BLACK CRUSTY LIPS
treatment = self resolving, corticosteroids prn
Chron's disease What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
inflammatory bowel disease
oral = labial swelling, apthous ulcers, mucosal tags, granulomatous gingiva
from anus to oral cavity
cobblestoning of GI tract
treatment = steroids/immunosuppressants (doesn’t cure)
Epilus fissuratum What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
hyperplastic fibrous connective tissue
sheet of fibrous CT
buccal vestibule
Associated with overextended denture flange
Treatment = excision if necessary, adjust denture flange
Inflammatory papillary hyperplasia What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
hyperplastic fibrous tissue papillary projections denture bearing areas (palate) caused by poor fitting dentures/24 hour wear treatment = better denture care
Denture leaf fibroma
leaf like fibroma on hard palate under a denture
Papilloma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Benign Warty projection of Squamous epithelium associated with HPV
rough surface with multiple finger like projections with pedunculated base
Verruca Vulgaris What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Benign Warty projection of Squamous epithelium associated with HPV
rough surface with multiple finger like projections with sessile base
single lesions
more common on skin
Condyloma
papilloma like growths, typically multiple and associated with high risk HPVs
What are the 5 P’s of gum bumps
parulis plain fibroma pyogenic granuloma peripheral ossifying fibroma peripheral giant cell granuloma
Parulis What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Gum bump formed from pus caused by infection of necrotic tooth canal that accumulated under epithelium
mass on the gums
gingiva
found near a necrotic tooth, doesn’t blanch, pus filled
Treatment = treat source of infection
Peripheral ossifying fibroma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Overgrowth of fibrous tissue
Red or pink growth
Gingiva
doesn’t blanch
Peripheral Giant Cell granuloma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Overgrowth of vascular tissue
Red/purple growth
gingiva
blanches
Pyogenic granuloma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
Overgrowth of vascular tissue
red/purple growth
gingiva
blanches, common in pregnancy
Plain Fibroma What is it? What is it's appearance? Where is it typically located? Key identifiers? Treatment?
overgrowth of fibrous tissue
firm pink growth
can be found anywhere
Doesn’t blanch
Do salivary lesions ever occur on attached gingiva
nope
What is the only tumor of neural origin that hurts
traumatic neuroma
What is the most common site of a Granular Cell tumor
dorsum of tongue
What are the tumors of muscle origin
leiomyoma (smooth muscle tumor) anywhere
Rhabdomyoma (skeletal muscle) not on palate or gingiva
What is the tumor of fat origin
lipoma (anywhere)
Congenital Epilus
Bump on the alveolar ridge that is present at birth