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PHI REVIEW > PATHOLOGY > Flashcards

PATHOLOGY Flashcards

1
Q

Most common form of testicular neoplasm in men > 60 years of age

A

Testicular lymphoma

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2
Q

Sex cord-stromal tumor with Crystalloids of Reinke (25%)

A

Leydig Cell Tumor

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3
Q

Embryonal Carcinoma with Schiller-Duval Bodies/glomeruloid (50%)

A

Yolk Sac Tumor

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4
Q

Tumor marker for prostatic adenocarcinoma when PSA is elevated but with normal biopsy

A

PCA 3 (Prostate Cancer Gene 3)

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5
Q

Most common site of prostate adenocarcinoma metastasis

A

Lumbar spine 》 proximal femur 》 pelvis 》 thoracic spine 》 ribs

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6
Q

Tennis racket cytoplasmic organelles

A

Birbeck granules/bodies in Langerhans cell histiocytosis

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7
Q

HPV type in condyloma acuminata

A

HPV 6, 11

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8
Q

Most common etiologic agents for pelvic inflammatory disease

A

Gonococcus and Chlamydia

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9
Q

Visual inspection of cervix with Lugol’s solution? High risk for cervical cancer if?

A

Schiller Test. (+) Pale staining areas

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10
Q

Schedule of Papanicolaou Smear

A

Start at 21 or within 3 years after first coitus, every 3 years until 30

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11
Q

Most common malignant germ cell tumor in females

A

Dysgerminoma

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12
Q

Second most common malignant germ cell tumor in females

A

Yolk sac tumor

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13
Q

Tumor marker for dygerminoma

A

KIT

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14
Q

Tumor marker for yolk sac tumor

A

AFP

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15
Q

Tumor marker for ovarian choriocarcinoma

A

HCG

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16
Q

Hydrothorax, ascites, ovarian tumor

A

Meig Syndrome

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17
Q

Sex-chord stromal tumors with Call-Exner bodies

A

Granulosa cell tumor

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18
Q

Signet ring GI carcinoma metastatic to the ovaries

A

Krukenberg tumor

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19
Q

Discohesive infiltrating tumor cells in single file (Indian file)

A

Invasive lobular carcinoma

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20
Q

Most common benign tumor of female breast

A

Fibroadenoma (stromal tumor)

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21
Q

Most common genetic abnormality in phyllodes tumor (stromal tumor)

A

Gains in Ch1q

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22
Q

Granulomatous thyroiditis causing thyrotoxicosis

A

De Quervain thyroiditis

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23
Q

Ovarian teratoma with ectopic thyroid causing thyrotoxicosis

A

Struma ovarii

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24
Q

MCC of congenital hypothyroidism worldwide

A

Congenital iodine deficiency

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25
MCC of hypothyroidism in iodine-sufficient areas
Hashimoto (Autoimmune)
26
Metaplastic response characterized by abundant, eosinophilic, granular cytoplasm in Hashimoto
Hurthle cell
27
Thyroid carcinoma with high levels of calcitonin but usually without hypocalcemia
Medullary thyroid carcinoma
28
Increase osteoclastic activity, peritrabecular fibrosis, cystic brown tumors
Von Recklinghausen disease of the bone
29
Nodular glomerulosclerosis of diabetes mellitus
Kimmelsteil-Wilson Disease
30
Massive bilateral adrenal hemorrhage as a complication of disseminated bacterial infection
Waterhouse-Friedrichsen Syndrome (Primary Acute Adrenocortical Insufficiency)
31
Bacteria associated with Waterhouse-Friedrichsen Syndrome
N. meningitidis
32
Cytogenetic origin of pheochromocytoma
Chromaffin cells
33
Rule of 10s in pheochromocytoma
10% extra-adrenal, 10% bilateral, 10% malignant, 10% NOT associated with hypertension
34
Prolactinoma (pituitary), Primary Hyperparathyroidism (parathyroid), Insulinoma or Gastrinoma (pancreas)
MEN 1 (Wermer Syndrome)
35
Mutation in Wermer Syndrome
MEN 1
36
MEN associated with parathyroid hyperplasia
MEN 2A (Sipple Syndrome)
37
MEN associated with neuromas, gangliomas, and Marfanoid habitus
MEN 2B
38
MEN 2 mutations
RET
39
Rapid increase in seborrheic keratosis as paraneoplastic syndrome of GI malignancies
Leser-Trelat sign
40
Lesions appear on sites of trauma in psoriasis
Koebner Phenomenon
41
Pinpoint bleeding on lifting of scales due to dilated tortuous vessels in dermal papillae
Auspitz Sign (Psoriasis)
42
Inflammatory infiltrates in psoriasis
Spongiform pustules of Kogoj and Munro microabscess
43
Impaired osteoclast function leads to excessive bone formation
Osteopetrosis (Marble Bone Disease) aka Albers-Schonberg Disease
44
First disorder to be treated with hematopoeitic stem cell transplantation
Osteopetrosis
45
Most common inherited disorder of connective tissue
Osteogenesis Imperfecta (Brittle Bone Disease)
46
Most common benign tumor of the liver
Hemangioma
47
Autosomal recessive disorder of copper metabolism
Wilson disease (hepatolenticular degeneration)
48
Oncogene activated in Pancreatic intraductal neoplasia 1A and 1B
KRAS oncogene
49
Gene mutation in PanIN2
p16 mutation
50
Gene mutation in PanIN3
p53, BRCA2, DPC4/SMAD4
51
Migratory thrombophlebitis in adenocarcinoma of the pancreas (sign)
Trousseau sign
52
Also known as strawberry gallbladder (yellow cholesterol-containing flecks in GB mucosal surface
Cholesterolosis
53
Also known as strawberry gallbladder (yellow cholesterol-containing flecks in GB mucosal surface)
Cholesterolosis
54
Apoptotic hepatocytes first identified in yellow fever
Councilman bodies
55
Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis
Mallory bodies
55
Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis
Mallory bodies
55
Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis
Mallory bodies
56
Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis
Mallory bodies
56
Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis
Mallory bodies
56
Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis
Mallory bodies
56
Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis
Mallory bodies

PHI REVIEW (6 decks)

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