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PHI REVIEW > PATHOLOGY > Flashcards

PATHOLOGY Flashcards

1
Q

Most common form of testicular neoplasm in men > 60 years of age

A

Testicular lymphoma

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2
Q

Sex cord-stromal tumor with Crystalloids of Reinke (25%)

A

Leydig Cell Tumor

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3
Q

Embryonal Carcinoma with Schiller-Duval Bodies/glomeruloid (50%)

A

Yolk Sac Tumor

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4
Q

Tumor marker for prostatic adenocarcinoma when PSA is elevated but with normal biopsy

A

PCA 3 (Prostate Cancer Gene 3)

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5
Q

Most common site of prostate adenocarcinoma metastasis

A

Lumbar spine 》 proximal femur 》 pelvis 》 thoracic spine 》 ribs

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6
Q

Tennis racket cytoplasmic organelles

A

Birbeck granules/bodies in Langerhans cell histiocytosis

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7
Q

HPV type in condyloma acuminata

A

HPV 6, 11

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8
Q

Most common etiologic agents for pelvic inflammatory disease

A

Gonococcus and Chlamydia

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9
Q

Visual inspection of cervix with Lugol’s solution? High risk for cervical cancer if?

A

Schiller Test. (+) Pale staining areas

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10
Q

Schedule of Papanicolaou Smear

A

Start at 21 or within 3 years after first coitus, every 3 years until 30

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11
Q

Most common malignant germ cell tumor in females

A

Dysgerminoma

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12
Q

Second most common malignant germ cell tumor in females

A

Yolk sac tumor

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13
Q

Tumor marker for dygerminoma

A

KIT

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14
Q

Tumor marker for yolk sac tumor

A

AFP

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15
Q

Tumor marker for ovarian choriocarcinoma

A

HCG

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16
Q

Hydrothorax, ascites, ovarian tumor

A

Meig Syndrome

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17
Q

Sex-chord stromal tumors with Call-Exner bodies

A

Granulosa cell tumor

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18
Q

Signet ring GI carcinoma metastatic to the ovaries

A

Krukenberg tumor

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19
Q

Discohesive infiltrating tumor cells in single file (Indian file)

A

Invasive lobular carcinoma

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20
Q

Most common benign tumor of female breast

A

Fibroadenoma (stromal tumor)

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21
Q

Most common genetic abnormality in phyllodes tumor (stromal tumor)

A

Gains in Ch1q

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22
Q

Granulomatous thyroiditis causing thyrotoxicosis

A

De Quervain thyroiditis

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23
Q

Ovarian teratoma with ectopic thyroid causing thyrotoxicosis

A

Struma ovarii

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24
Q

MCC of congenital hypothyroidism worldwide

A

Congenital iodine deficiency

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25
Q

MCC of hypothyroidism in iodine-sufficient areas

A

Hashimoto (Autoimmune)

26
Q

Metaplastic response characterized by abundant, eosinophilic, granular cytoplasm in Hashimoto

A

Hurthle cell

27
Q

Thyroid carcinoma with high levels of calcitonin but usually without hypocalcemia

A

Medullary thyroid carcinoma

28
Q

Increase osteoclastic activity, peritrabecular fibrosis, cystic brown tumors

A

Von Recklinghausen disease of the bone

29
Q

Nodular glomerulosclerosis of diabetes mellitus

A

Kimmelsteil-Wilson Disease

30
Q

Massive bilateral adrenal hemorrhage as a complication of disseminated bacterial infection

A

Waterhouse-Friedrichsen Syndrome (Primary Acute Adrenocortical Insufficiency)

31
Q

Bacteria associated with Waterhouse-Friedrichsen Syndrome

A

N. meningitidis

32
Q

Cytogenetic origin of pheochromocytoma

A

Chromaffin cells

33
Q

Rule of 10s in pheochromocytoma

A

10% extra-adrenal, 10% bilateral, 10% malignant, 10% NOT associated with hypertension

34
Q

Prolactinoma (pituitary), Primary Hyperparathyroidism (parathyroid), Insulinoma or Gastrinoma (pancreas)

A

MEN 1 (Wermer Syndrome)

35
Q

Mutation in Wermer Syndrome

A

MEN 1

36
Q

MEN associated with parathyroid hyperplasia

A

MEN 2A (Sipple Syndrome)

37
Q

MEN associated with neuromas, gangliomas, and Marfanoid habitus

A

MEN 2B

38
Q

MEN 2 mutations

A

RET

39
Q

Rapid increase in seborrheic keratosis as paraneoplastic syndrome of GI malignancies

A

Leser-Trelat sign

40
Q

Lesions appear on sites of trauma in psoriasis

A

Koebner Phenomenon

41
Q

Pinpoint bleeding on lifting of scales due to dilated tortuous vessels in dermal papillae

A

Auspitz Sign (Psoriasis)

42
Q

Inflammatory infiltrates in psoriasis

A

Spongiform pustules of Kogoj and Munro microabscess

43
Q

Impaired osteoclast function leads to excessive bone formation

A

Osteopetrosis (Marble Bone Disease) aka Albers-Schonberg Disease

44
Q

First disorder to be treated with hematopoeitic stem cell transplantation

A

Osteopetrosis

45
Q

Most common inherited disorder of connective tissue

A

Osteogenesis Imperfecta (Brittle Bone Disease)

46
Q

Most common benign tumor of the liver

A

Hemangioma

47
Q

Autosomal recessive disorder of copper metabolism

A

Wilson disease (hepatolenticular degeneration)

48
Q

Oncogene activated in Pancreatic intraductal neoplasia 1A and 1B

A

KRAS oncogene

49
Q

Gene mutation in PanIN2

A

p16 mutation

50
Q

Gene mutation in PanIN3

A

p53, BRCA2, DPC4/SMAD4

51
Q

Migratory thrombophlebitis in adenocarcinoma of the pancreas (sign)

A

Trousseau sign

52
Q

Also known as strawberry gallbladder (yellow cholesterol-containing flecks in GB mucosal surface

A

Cholesterolosis

53
Q

Also known as strawberry gallbladder (yellow cholesterol-containing flecks in GB mucosal surface)

A

Cholesterolosis

54
Q

Apoptotic hepatocytes first identified in yellow fever

A

Councilman bodies

55
Q

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

A

Mallory bodies

55
Q

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

A

Mallory bodies

55
Q

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

A

Mallory bodies

56
Q

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

A

Mallory bodies

56
Q

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

A

Mallory bodies

56
Q

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

A

Mallory bodies

56
Q

Intracytoplasmic eosinophilic hyaline inclusions in alcoholic hepatitis

A

Mallory bodies

PHI REVIEW (6 decks)

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