Pathology Flashcards
Triad of aspirin-intolerance?
- asthma (LOX overactive - lots of LT’s and resultant bronchoconstriction)
- asp-induced bronchospasms
- nasal polyps
Three situations in which nasal polyps are seen?
- repeated bouts of rhinitis
- cystic fibrosis (beware in kids)
- aspirin-intolerant asthma
Benign tumor of nasal mucosa composed of large BV’s and fibrous tissue? Population? Presentation?
- angiofibroma
- adolescent males
- profuse epistaxis
Organism associated with acute epiglottitis?
- H. influenzae type b
- pediatric emergency due to risk of airway obstruction
Common cause of laryngotracheobronchitis? Common name?
- parainfluenza virus
- croup
Benign papillary tumor of vocal cord? Viral association?
- laryngeal papilloma
- low-risk HPV 6 and 11 associated with genital warts (16 and 18 are high risk) = poikilocytosis
Why is pleuritic pain occur in pneumonia?
- pleura is sensitized to pain due to release of PGE2 and bradykinin from inflammation = pain mediators
Common physical exam findings in pneumonia?
- tachypnea with pleuritic chest pain
- decreased breath sounds
- dullness to percussion
Four classic gross phases of lobar pneumonia?
- congestion
- red hepatization
- gray hepatization
- resolution (Type II cell epithelial regeneration)
What pneumonia patterns are associated with bacteria? Viruses? Anaerobic bacteria?
- lobar and bronchopneumonia
- interstitial (atypical) pneumonia
- aspiration pneumonia - oropharynx anaerobes
Three anaerobes commonly associated with aspiration pneumonia?
- Bacteroides
- Fusobacterium
- Peptococcus
Which organism is commonly transmitted from a water source?
Legionella pneumophila (silver stain)
Two common causes of atypical pneumonia in young adults?
- Mycoplasma pneumoniae
- Chlamydia pneumoniae
Two common causes of lobar pneumonia?
- Strep pneumoniae: most common cause of CAP and secondary pneumonia
- Klebsiella pneumoniae: enteric flora that is aspirated = capsular jelly sputum + abscess
Organism in atypical pneumonia with post-transplant immunosuppressive Tx?
CMV (herpes virus)