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Hematology > Pathology > Flashcards

Pathology Flashcards

1
Q

How to differentiate between B12 and folate deficiency

A

B12 deficiency has increased methylmalonic acid

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2
Q

Why does protein aciduria occur

A

Orotic acid not able to convert to UMP
Due to defiance of UMP synthetase

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3
Q

How to differentiate between orotic aciduria and ornithina transcarbamoyl deficiency?

A

Orotic aciduria has orotic acid in urine with no hyperammonemia
The latter has hyperammonemia

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4
Q

Treatment of orotic aciduria

A

Uridine monophosphate or uridine triacetate

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5
Q

Diamond blackfan deficiency is what type of anemia

A

Non megaloblastic macrocyclic anemia

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6
Q

Presentation of diamond blackfan

A

Pure red cell aplasia
Anemia onset within 1st year of life

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7
Q

Total hb in blackfan

A

Decreased but HBF is increased

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8
Q

What is the cause of aplastic anemia

A

Reduce Volume From Inside Diaphysis
Radiation
Virus - EBV PARVOVIRUS
Fanconi anemia
Idiopathic
Drugs - alkylation agents, chloramphenicol, benzene

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Hematology (3 decks)

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