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OMSITE > Pathology > Flashcards

Pathology Flashcards

1
Q

Most common type of Basal Cell Carcinoma?

A

Nodular

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2
Q

Differentiating between Ossifying fibroma and fibrous dysplasia?

A

Fibrous Dysplasia will show strong immunoreactivity for osteocalcin and GNAS mutation on PCR.

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3
Q

Management of Ossifying Fibroma

A

Complete Enucleation.

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4
Q

Management of Fibrous Dysplasia

A

Non-surgical.
Bisphosphonates.

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5
Q

What percentage of patients over 40 have Osteoarthritis?

A

10% of men and 13% of women have symptomatic osteo arthritis of knee. 25% of patients have radiographic evidence of knee.

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6
Q

ORNJ Stages

A

0= non-exposed bone
1= exposed necrotic bone or fistulae that probes to bone; no infection
2= 1+ infection
3= 2 + pathologic fracture- or extends to inferior border or sinus floor or communicates with antrum.

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7
Q

Why is BRONJ now called MRONJ

A

Denosumab (Rani-L inhibitor)

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8
Q

Lesion associated with impacted canine?

A

Adennomatoid Odontogenic Tumor

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9
Q

Aspergillosis branching

A

ACUTE angles

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10
Q

Mucormycosis Branching

A

Right or Obtuse angles. Tx: Amphotericin B

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11
Q

Pemphigus vulgaris affects?

A

Desmoglein 3
-Fish net pattern

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12
Q

Pemhagoid Immunofluorescence pattern?

A

Linear.
Attacks basement membrane.

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13
Q

Central feature of Calcifying Odontogenic cyst

A

Ghost cells. Generally radiolucent but sometimes with calcifications within.

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14
Q

Central giant cells occur predominantly….

A

In Anterior mandible of young adults.

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15
Q

Most common type of osteosarcoma

A

Chondroblastic osteosarc.

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16
Q

Most common type of rhabdosarcoma?

A

Embryonic

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17
Q

Lesion on palate with palisaded spindle cells, painful and S100 positive

A

Schwanoma.
S100 found in melanomas, neurofibromas, and nerve sheath tumors.

18
Q

Most common types of rhabdomyosarcoma of the H&N.

A

Embryonal, then alveolar, and pleomorphic

19
Q

Most common type of osteosarcoma of the H&N

A

Chondroblastic then Osteoblastic, then Fibroblastic.

20
Q

Radiation for SCC of floor of mouth

A

Optional in N0 unless positive margin or high risk features.
Always in N1+ ds. Consists of 60-70 Gy 6-7 weeks post op or 44-55Gy if low/intermediate risk. Or higher risk 72Gy +. Radiation Sarcoma is a risk over 40Gy.

21
Q

Trigeminal neuralgia has paroxysmal or continuous pain

A

Paroxysmal

22
Q

What non-malignant jaw lesions need a resection?

A

All ameloblastomas, CEOT, Myxoma, Odontoameloblastoma.

23
Q

Tx of OKC

A

Enucleation with peripheral ostectomy and or cryotherapy.

24
Q

Aneurysmal bone cyst

A

Develops secondarily from another bone lesion. Usually Central Giant Cell.

25
Q

Giant cell lesion marker

A

CD68

26
Q

Radical neck dissection removes

A

Zones 1-5 + spinal accessory nerve, IJ + SCM.

27
Q

Modified radical neck dissection removes

A

Type 1 preserves spinal accessrry nerve
Type 2 preserves spinal accessory. nerve and IJ
Type 3 preserves SAN, IJV, SCM.

28
Q

Selective neck dissection remmoves

A

Just specified levels of lymph tissue. For most oropharyngeal lesions a level 2-4 SND is done.

29
Q

What salivary gland tumor is almost exclusively minor gland?

A

Polymorphous Low-grade Adenocarcinoma.

30
Q

When is the best time to remove an AVM after embolization

A

1-3 days

31
Q

Bone mets to the jaw come from

A

Breast then lung in women.

32
Q

How to treat ulcerative stomatitis?

A

Hydroxychloroquine.

33
Q

What does cavernous sinus thrombosis affect first?

A

CN 6- abducens nerve.

34
Q

Borders of retropharyngeal space infection?

A

Buccopharyngeal fascia anteriorly and prevertebral fascia posteriorly

35
Q

Treatment for chondrosarcoma?

A

Low grade= 1.5cm bony and soft tissue margins. High grade= 3cm bony and 2cm soft tissue margins with pre and post surgery chemotherapy.

36
Q

Treatment of 0.5cm pleomorphic adenoma in parotid?

A

Superficial parotidectomy.

37
Q

MEN I

A

3 Ps pituitary, parathyroid, pancreas.

38
Q

MEN IIa

A

1M, 2Ps. Medullary thyroid, pheochromocytoma, parathyroid

39
Q

MEN 2b

A

2Ms, 1P. Medullary Thyroid, Marfanoid habitus/Mucosal neuromas and pheochromocytoma.

40
Q

What are the most common malignant tumors of minor and major salivary glads?

A

Mucoepidermoid Carcinoma in the parotid

Adenoid cystic carcinoma in the submandibular, sublingual, and salivary glands.

41
Q

What is the most common benign tumor of minor and major salivary glands?

A

Pleomorphic adenoma.

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