Pathology Flashcards
Area of science focusing on all the changes of cells, tissues, and organs that underly a disease.
Pathology
Refers to the cause of disease.
Etiology
Manner of how the disease developed.
Pathogenesis
Basic unit of life.
Cell
Incomplete/defective development of tissue/organ.
Aplasia
Complete NON-APPEARANCE of an organ.
Agenesia
Failure of an organ to reach normal mature adult size.
Hypoplasia
Failure of an organ to form an opening.
Atresia
Affected cell can return to its normal state by using several cellular adaptation mechanisms.
Reversible Injury
Can no longer return to its normal state. Considered as the “point of no return”
which may lead to cell death.
Irreversible Injury
Types of cell death: Physiologic and Normal Process.
Apoptosis
Types of cell death: Pathologic and Due to a disease.
Necrosis
Acquired decrease in tissue or organ size.
Atrophy
Occurs as a consequence of maturation.
Physiologic Atrophy
Decrease in tissue or organ size is due to a disease.
Pathologic Atrophy
caused by sudden cut off of blood supply.
Vascular Atrophy
May happen due to lack of nutritional supply.
Starvation/Hunger Atrophy
May develop due to excessive workload.
Exhaustion Atrophy
May occur due to lack of hormones needed to maintain the normal size of a tissue/organ.
Endocrine Atrophy
May occur due to inactivity or diminished function.
Atrophy of Disuse
Persistent pressure on a tissue/organ may cause direct injury to the cell causing to a decrease in size.
Pressure Atrophy
There is an increase in tissue/organ size due to the increase in the SIZE of individual cells comprising the organ. No NEW CELLS are produced.
Hypertrophy
May happen if one of the paired organs is removed.
Compensatory Hyperthrophy