Pathology Flashcards

1
Q

Area of science focusing on all the changes of cells, tissues, and organs that underly a disease.

A

Pathology

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2
Q

Refers to the cause of disease.

A

Etiology

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3
Q

Manner of how the disease developed.

A

Pathogenesis

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4
Q

Basic unit of life.

A

Cell

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5
Q

Incomplete/defective development of tissue/organ.

A

Aplasia

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6
Q

Complete NON-APPEARANCE of an organ.

A

Agenesia

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7
Q

Failure of an organ to reach normal mature adult size.

A

Hypoplasia

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8
Q

Failure of an organ to form an opening.

A

Atresia

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9
Q

Affected cell can return to its normal state by using several cellular adaptation mechanisms.

A

Reversible Injury

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10
Q

Can no longer return to its normal state. Considered as the “point of no return”
which may lead to cell death.

A

Irreversible Injury

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11
Q

Types of cell death: Physiologic and Normal Process.

A

Apoptosis

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12
Q

Types of cell death: Pathologic and Due to a disease.

A

Necrosis

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13
Q

Acquired decrease in tissue or organ size.

A

Atrophy

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14
Q

Occurs as a consequence of maturation.

A

Physiologic Atrophy

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15
Q

Decrease in tissue or organ size is due to a disease.

A

Pathologic Atrophy

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16
Q

caused by sudden cut off of blood supply.

A

Vascular Atrophy

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17
Q

May happen due to lack of nutritional supply.

A

Starvation/Hunger Atrophy

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18
Q

May develop due to excessive workload.

A

Exhaustion Atrophy

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19
Q

May occur due to lack of hormones needed to maintain the normal size of a tissue/organ.

A

Endocrine Atrophy

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20
Q

May occur due to inactivity or diminished function.

A

Atrophy of Disuse

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21
Q

Persistent pressure on a tissue/organ may cause direct injury to the cell causing to a decrease in size.

A

Pressure Atrophy

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22
Q

There is an increase in tissue/organ size due to the increase in the SIZE of individual cells comprising the organ. No NEW CELLS are produced.

A

Hypertrophy

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23
Q

May happen if one of the paired organs is removed.

A

Compensatory Hyperthrophy

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24
Q

Hypertrophy due to a disease.

A

Pathologic Hypertrophy

25
There is an increase in tissue/organ size due to increased NUMBER of cells comprising the organ.
Hyperplasia
26
Involves transformation of adult cells into another adult cells.
Metaplasia
27
Also known as Pre-neoplastic Lesion/Atypical Metaplasia.
Dysplasia
28
Transformation of adult cells into primitive or embryonic cell type. Also known as De-Diiferentiation.
Anaplasia
29
Process of tumor formation.
Neoplasia
30
study of tumors or neoplasms.
Oncology
31
_____ is a type of cell death that is programmed; Cell shrinkage; No leakage of cellular contents.
Apoptosis
32
_____ is a type of cell death that is due to a disease; Cell swelling; Cellular contents leaked out
Necrosis
33
Cardinal signs of inflammation: _____ - redness; due to increase dilation of blood vessels
Rubor
34
Cardinal signs of inflammation : _______ - pain; due to release of chemical substances
Dolor
35
Cardinal signs of inflammation : _______ - Heat; transfer of internal heat to the site of injury of tissue
Calor
36
Cardinal signs of inflammation : _______ - swelling; due to the extravascular accumulation of fluid
Tumor
37
Cardinal signs of inflammation : _______ - destruction of the functioninh units of tissue
Function laesa
38
________ refers to the death of the entire body; changes that can be noted in the body
Somatic death
39
_______ is a common term for all malignant tumors
Cancer
40
________ is a tissue reaction to injury "itis", a complex reaction to various injurious agents
Inflammation
41
Changes that can be noted/observed IMMEDIATELY AFTER DEATH
Primary changes
42
Changes that can be noted FEW HOURS AFTER DEATH
Secondary changes
43
_______ - Cooling of the body; first secondary change to appear
Algor Mortis
44
_____ - Rigidity ; stiffening of muscles
Rigor Mortis
45
_____ - purplish discoloration of skin due to sinking of fluid blood into the capillaries of the dependent parts
Livor mortis / lividity / post mortem hemolysis
46
______- blood will clot
Post mortem clotting
47
Destruction of cells or tissues
Autolysis
48
Release of foul odor due to increase (bacterial decomposition) in saprophytic organ
Putrefaction
49
Drying and wrinkling of the anterior chamber of the eyeand cornea
Dessication
50
It involves examination fo dead body
Autopsy
51
Most important requirement for autopsy is?
Get a CONSENT from the nearest kin of the patient
52
______ - cadaver is opened from both shoulders down from the xiphoid area; usually done in adult cadavers
Y-shaped incision
53
_______ cadaver is opened from midline of the body from the suprasternal notch down to the pubis ; commonly done in children and infants
Straight cut incision
54
Principal techniques of autopsy: The organs are removed from the body ONE BY ONE
Technique by RUDOLF VIRCHOW
55
Principal techniques of autopsy: "In situ dissection" Dissection is carried out in its original place
Technique by KARL ROKITANSKY
56
Father of modern pathology
RUDOLF VIRCHOW
57
"en-bloc" removal of organs; Organs are removed by group
Technique by ANTON GHON
58
"en-masses" removal of organs; ALL organs are removed at same time
Technique by M. LETULLE (LETTULE)