Pathologies requiring therapeutic anticoagulants

Question 1

Hypercoagulable state

Answer 1

Certain individuals have a higher disposition to thrombosis
risk - having an inherited or acquire thrombophilia defect, medical conditions

Question 2

Forming a thrombus

Answer 2

Hyper-coagulable state
Increase risk of fibrin clot forming - thrombus
Can become embolus

Question 3

What are anti-coagulants?

Answer 3

Inhibit or reduce normal functioning of the coagulation system
Intravenous/subcutaneous anticoagulants - heparins and heparin derivaties

Question 4

Therapeutic use of anticoagulants

Answer 4

Acquired coagulopathies - atrial filtration, deep vein thrombosis, pulmonary embolism
Inherited coagulopathies - Protein C deficiency, Protein S deficiency

Question 5

Incraesed risk of thrombosis

Answer 5

Secondary causes of coagulaopthy
Lifestyle
Chronic inflammation
Statsis
Surgery

Question 6

Determination of pathological throbus

Answer 6

Clinical suspicion
Coagulation screen
If postiive - imaging, doppler

Question 7

Therapeutic management

Answer 7

Balance - risk of thrombosis, risk of haemorrhage