Pathologies Flashcards

1
Q

Prions cause what type of diseases?

A

spongiform encephalopathy
Creutzfeldt-Jakob disease
Mad cow disease

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2
Q

What is the relationship of ALT and AST in viral vs. alcoholic hepatitis?

A

viral: ALT > AST
alcoholic: ALT

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3
Q

where is the most common place to have a paradoxical emboli?

A

brain due to prior CHD

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4
Q

What bacteria causes acute bacterial endocarditis?

A

S. aureus

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5
Q

What bacteria causes subacute bacterial endocarditis?

A

Viridans strep (alpha-hemolytic)

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6
Q

If a patient has a tricuspid valve vegetation what cause should you suspect?

A

intravenous drug use

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7
Q

what bacteria is associated with prosthetic hart valves?

A

staph epidermidis

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8
Q

What bacteria can cause pathologies by entering the bloodstream during dental procedures?

A

Strep. mutans

Strep. mitis

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9
Q

What bacteria causes hypovolemic shock via rice water diarrhea?

A

vibrio cholera

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10
Q

What is the only G+ to have an endotoxin?

A

listera

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11
Q

Most common location for atherosclerotic induced aneurysm?

A

abdominal aorta

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12
Q

What are the collagen vascular diseases?

A
RA
SLE
Polyarteritis nodosa
Dermatomyositis
Scleroderma
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13
Q

What’s the S/S of pseudo gut?

A

Calciumpyrophosphate deposits in joints

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14
Q

Serum marker of inc osteoclast activity

A

hydroxyproline

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15
Q

Serum marker of inc osteoblast activity

A

Alkaline phosphatase

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16
Q

What neoplasms are EBV associated with?

A

Burkitt’s lymphoma
Nasopharyngeal carcinoma
B-cell lymphoma
Hairy leukoplakia

17
Q

4 Conditions associated with Teratlogy of Fallot (children)

A

Dextroposed (overridden aorta)
Pulmonic stenosis
VSD
RV hypertrophy

18
Q

S/S of Edward syndrome (trisomy 18)

A

Micrognathia

Rock bottom feet

19
Q

S/S of Patau syndrome (trisomy 13)

A

microcephaly

cleft

20
Q

S/S of Turner syndrome

A

Primary amenorrhea
Webbed neck
Short
Coarctation of aorta

21
Q

Hyperthyroidism can cause what diseases

A

Plummer disease

Graves disease

22
Q

Hypothyroidism can cause what diseases

A

Myxedema (adults)
Cretinism (children)
Hashimoto’s Disease

23
Q

S/S of hypothyroidism i children

A

underdeveloped mandible, delayed eruption, retinaed decidduous teeth

24
Q

hyperparathyroidism can cause what disease and S/S?

A

von Recklinghausen disease (osteitis fibrosa cystica)
S/S: osteolytic lesions, dec. serum phosphorus
inc. serum Ca and alkaline phosphatase

25
Q

Reed-Sternberg cells are associated with what neoplasm?

A

Hodgkins

26
Q

Philadelphia chromosome is associated with what neoplasm?

A

Myelogenous leukemia

27
Q

Bence-Jones protein in urine is a sign of what neoplasm

A

Multiple myeloma

28
Q

S/S of multiple myeloma

A

Inc plasma cells: dec RBC, platelets, WBC
Osteolyitc lesions and bone pain
hypercalcemia
Amyloidosis

29
Q

What are the histiocytosis X pathologies?

A

Eosinophilic granuloma
Letterer-Side disease
Hand-Schuller-Christina disease

30
Q

Most common cancer

A

basal cell carcinoma

31
Q

Vit B1 (thiamine) deficiency

A

Beriberi: dry skin, progressive paralysis

linked to alcoholism

32
Q

Vit B2 (riboflavin) deficiency

A

angular chelitis
dermatitis
glossitis

33
Q

Vit B3 (Niacin) deficiency

A

Pellagra: diarrhea, dermatitis, dementia

34
Q

Folate deficiency

A

megaloblastic anemia, glossitis, diarrhea, homocystinemia

causes: alcoholism, pregnancy