Pathologie maladies spécifiques - Bovins paratuberculose Flashcards

1
Q

Étiologie

A

Mycobacterium avium ssp. paratuberculosis (Map)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Pathogénie :

  • age infection
  • age dev SC
A

Moins 30 jours âge

2 ans et plus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Pathogénie

A

Contamination paturages, eau et aliments par fumier contaminé OU colostrum/lait

Ingestion –> activation FAP
Infection macrophages
- Blocage acidification et maturation phagosome en inhibant la fusion phagosome avec lysosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Principal mécanisme immunitaire pour contrôle condition

A

Immunité cellulaire Th1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

SC Bovins

A

D+ intermittente à chronique

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

SC PRum

A

10-30% avec D+ ou fèces molles (meilleure réabsorption eau dans côlon)
–> DÉPÉRISSEMENT PROGRESSIF SURTOUT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

SC Bo et PRum

A

Perte de poids progressive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Lésions macro bovins

A

Entérite granulomateuse iléon terminal et côlon proximal
Lymphangite intestinale
Lymphadénopathie mésentérique
Minéralisation sous-endocardique

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Lésions macro PRum

A

Pas lésions (dépérissement progressif +)

Sinon Lymphangite > Lymphadénopathie > lésions intestinale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Lésions micro

A

Entérite granulomateuse diffuse
Lymphangite intestinale pyogranulomateuse
Lymphadénite granulomateuse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Formes retrouvées à coloration Ziehl-Neelsen (2) ?

A

Pluribacillaire (lépromateuse) si bcp bactéries

Paucibacillaire (tuberculoide) si pas bcp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dx ante-mortem

A

Grattage muqueuse rectale 60%

Biopsies intestinales = gold standard

How well did you know this?
1
Not at all
2
3
4
5
Perfectly