pathogens quiz Flashcards
Prokaryotic
-lack of nucleus; and other membrane organelles
-single celled organisms
-Domains: Archea and bacteria
-0.5-2 um in diameter
-large surface to volume ration (3:1)
Archea
no diesease causing organisms; thermophiles, e
Eukaryotic
-contain a nucleus and other membrane bound structures
-plants, animals, fungi, protists
Bacteria arrangement
-Diplo (2) - in on plane
-tetra (4) - in two planes
-sarcinan (8)- in three planes
-Bacillus- in one plane end to end making chains; rods that make chains
prokaryotic peptidoglycan components
- Sugar backbone
2.tetra peptide crosslinkers - penta glycine bridge
prokaryotic peptidoglycan function
-maintains shape
-prevent lysis
-water passes thru via osmosis
-no real regulation of materials
if peptidoglycan is enzymatically dissolved
Gram negative cell wall peptidogylcan
-DAP- type; sugar backbone, tetra peptide
Gram negative periplasmic space
-digestive space
-protein pumps
-bacterial toxin
3 Antigens
O- Cell wall
K- capsule
H-Flagella
Gram negative cells (outer membrane)
fluid mosaic model (lipid + many sugars
Gram positive cells peptidogylcan
- sugar backbone
- tetra
- penta
Gram positive cells periplasm
semi solid structure
Acid fast cell walls
- lipids
- peptodpgyclan
ecto
-on/outside
-ticks, fleas
endo
-in/inside
-virus, tapeworm
obligate
-must be with a host
farulatiative
-can have free living stages
permanent
whole life
temporary
on and off
definitive host
host where sexual replication occurs “adult stage.”
intermediate host
any other stage
reservoir host
place where pathogen survives and thrives -jump or move to human.
parasite envasion strategies
avoiding death by the immune responses
host cell invasion
-enter our cells
-extracellular environment to intracellular
immunological challenges
parasite will change outer protein and carbohydrate coat.
encystment
enter into stasis inside a structure, created by the parasite
damage to the host caused by patasite
nutritional deprivation
direct trauma. obstruction
inflammation/ immunological reaction
Gram negative periplasmic space
-digestive space
-protein pumps
-bacterial toxin
