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Periodontics I > Pathogenesis of Periodontal Disease (9/20) > Flashcards

Pathogenesis of Periodontal Disease (9/20) Flashcards

1
Q

What are 5 components of microbial plaque?

A
  • bacteria
  • fungus
  • protozoa
  • virus
  • mycoplasm
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2
Q

What 3 factors contribute to periodontal disease?

A
  • microbial plaque
  • genetics/host factors
  • acquired/environmental factors
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3
Q

What are the 2 types of supragingival plaque?

A
  • coronal plaque

- marginal plaque

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4
Q

What are the 2 types of subgingival plaque?

A
  • attached plaque

- unattached

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5
Q

What are the 3 types of attached plaque?

A
  • tooth
  • epithelium
  • connective tissue
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6
Q

What are the 5 cardinal signs of inflammation?

A
  • redness (rubor)
  • swelling (tumor)
  • heat (calor)
  • pain (dolor)
  • loss of function (functiolaesa)
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7
Q

What are the 5 cardinal signs of inflammation?

A
  • redness (rubor)
  • swelling (tumor)
  • heat (calor)
  • pain (dolor)
  • loss of function (functiolaesa)
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8
Q

What are the underlying host response events that are the basis for the clinical findings seen in gingivitis and periodontitis?

A

-

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9
Q

What is the relationship between periodontal disease and systemic effects?

A

-

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10
Q

T/F: Increased epithelial turnover rate may result in a lack of keratinization.

A

True.

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11
Q

What is the major cell type found in inflammatory cell infiltrate?

A

PMNs

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12
Q

When does the initial lesion occur?

A

2-4 days

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13
Q

What are the histologic features of an initial lesion?

A
  • vasculitis of vessels in JE
  • exudate from gingival sulcus
  • increased leukocytes into JE & gingival sulcus
  • presence of serum proteins (fibrin)
  • increased vascularity
  • alteration to coronal JE
  • loss of perivascular collagen
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14
Q

What is the clinical appearance of the initial lesion?

A
  • appears clinically healthy
  • no periodontal pocket
  • no radiographic evidence of bone loss
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15
Q

When does the early lesion occur?

A

4-7 days

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16
Q

What are the histologic features of the early lesion?

A
  • accentuation of initial lesion
  • lymphoid cells in JE
  • further loss of collagen fiber network of marginal gingiva
  • beginning proliferation of basal cells of JE
17
Q

What are the clinical features of the early lesion?

A
  • gingivitis (acute)
  • changes in gingival color, contour, and consistency
  • bleeding on probing
  • no pocket
  • no bone loss
18
Q

When does the established lesion occur?

A

2-3 weeks

19
Q

What are the histologic features of an established lesion?

A
  • predominance of plasma cells without bone loss
  • immunoglobulins in CT & JE
  • continuing loss of CT
  • proliferation, apical migration, and lateral extension of JE
  • early pocket formation may or may not be present
20
Q

What are the clinical features of the established lesion?

A
  • gingivitis
  • changes in color, contour, and consistency of gingiva
  • bleeding on probing
  • no pocket
  • no bone loss
21
Q

When does the advanced lesion occur?

A

> 3 weeks

22
Q

What are the histologic features of the advanced lesion?

A
  • significant bone loss
  • loss of collagen in pocket epithelium
  • cytopathically altered plasma cells
  • formation of periodontal pockets
  • periods of quiescence and exacerbation
  • conversion of distant bone marrow into fibrous CT
  • widespread manifectations of inflammatory/immunopathologic reactions
23
Q

What are the clinical features of the advanced leasion?

A
  • periodontitis
  • changes in gingival color, contour, and consistency
  • pocket formation
  • alveolar bone loss
24
Q

What is the innate immune response?

A

non-specific

25
Q

What is the acquired immune response?

A
  • adaptive

- specific

26
Q

T/F: Both innate and acquired immune responses are required for host immune competency.

A

True.

27
Q

T/F: Both innate and acquired immune responses are required for host immune competency.

A

True.

28
Q

T/F: It is widely accepted that the initiation and progression of periodontitis are dependent on the presence of microorganisms capable of causing disease.

A

True.

29
Q

What cell causes the most damage to the CT in periodontitis?

A

Fibroblast when stimulated in the immune response.

Periodontics I (3 decks)

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