pathogen p1 Flashcards
What should you be able to recognize in periodontal pathogenesis?
Various immune system elements involved in periodontal pathogenesis.
What is the role of immune receptors in periodontal pathogenesis?
They signal different responses, leading to bystander damage.
Describe the histopathological stages of periodontal diseases and their clinical presentation.
Stages and signs of disease progression like inflammation and tissue damage.
What is periodontal disease pathogenesis?
The molecular immune response mechanism causing periodontal tissue changes.
What is the purpose of understanding PD pathogenesis?
To understand clinical and histopathological changes in the periodontium.
How do microorganisms directly affect the periodontium?
By releasing toxins causing tissue damage.
What is the role of the immune system in indirect periodontal damage?
Immune responses to pathogens can lead to bystander damage.
What are polymorphonuclear leukocytes (PMNs)?
PMNs are immune cells crucial for bacterial defense in the periodontium.
How do macrophages contribute to periodontal pathogenesis?
They perform phagocytosis and secrete inflammatory mediators.
What is bystander damage in periodontal disease?
Tissue damage caused indirectly by immune responses to pathogens.
What immune cells are typically involved in bystander damage?
Mainly PMNs and macrophages releasing reactive molecules.
What represents the immune system in the war analogy for PD?
The immune system acts as ‘Army Forces’ fighting pathogens.
In the war analogy, who are the ‘Invaders’?
Microorganisms invading and attacking periodontal tissues.
What is the ‘Battlefield’ in periodontal disease?
The periodontium where immune cells and pathogens interact.
What role does the periodontium play in immune response?
It’s the site where immune cells meet and combat pathogens.
What type of immune cells are known as the ‘first responders’?
PMNs or neutrophils, which attack pathogens immediately.
How do PMNs affect periodontal tissue in the battle?
Their actions can cause collateral damage to surrounding tissues.
How does macrophage action relate to the ‘invaders’ analogy?
They target invaders and present antigens to other immune cells.
Define periodontal disease (PD) pathogenesis.
The immune mechanism causing tissue changes in response to pathogens.
What responses are involved in PD pathogenesis?
Inflammatory and immune responses working to combat pathogens.
How does PD pathogenesis begin?
It starts with pathogen invasion and immune response activation.
What cells are involved in the inflammatory response of PD?
Mast cells, PMNs, and macrophages.
How does vasodilation aid immune response in PD?
Increases blood flow, allowing immune cells to reach affected tissue.
What mediators are released in inflammation?
Histamine and cytokines like IL-1 and TNF-alpha.
