Patho Flashcards

1
Q

Mc leukaemia in childern

A

ALL

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2
Q

Mc leukaemia in adults

A

CLL

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3
Q

Philadelphia chromosome no

A

Chr t (9;22)

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4
Q

Chr t (9;22) is a/w which leukemia

A

CML

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5
Q

Hodgkin’s lymphoma marker

A

CD 15, CD30

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6
Q

Leukemia not a/w radiation

A

CLL

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7
Q

Cmyc translocation is a/w

A

Burkit lymphoma- most aggressive type of NHL

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8
Q

Smudge cells/ basket cells are seen in which leukemia?

A

CLL

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9
Q

Auer rods are seen in which leukemia?

A

AML M3

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10
Q

Mc leukemia seen in Down syndrome?

A

AML M7

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11
Q

Acute promyelocytic leukemia chr translocation?

A

Chr t (15;17)

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12
Q

Hairy cell leukemia marker

A

CD 103

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13
Q

Burkit lynphoma a/w which translocation?

A

Chr t (8;14)

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14
Q

1st enzyme To increase in MI

A

Myoglobin

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15
Q

Which enzyme comes to normal level within 24hrs

A

Myoglobin

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16
Q

Which enzyme is not specific for mi

A

Myoglobin

17
Q

Which enzyme is useful for dx of mi but also increases in myocarditis

A

CK MB

18
Q

Troponin I increases within how many hrs after mi

A

24-48 hrs

19
Q

Trop I remains elevated for how many days post mi?

A

7-10 days

20
Q

Most specific and sensitive enzyme to dx mi

A

Trop I

21
Q

Which enzyme is useful to dx re infarction of mi

A

Trop I

22
Q

Normal person has which ldh more?

A

LDH 2 more than LDH 1

23
Q

Which ldh is increased in person with mi

A

LDH1 more than LDH2

24
Q

Which is the last enzyme to increase in mi

A

LDH

25
Q

What are the changes occurs on biopsy within 4 hrs of post MI?

A

No change

26
Q

What are the changes occurs on biopsy within 4-24 hrs of post MI?

A

Intercellular edema
Waviness of fibres
Pale on ttc staining

27
Q

What are the changes occurs on biopsy within 24-72 hrs of post MI?

A

Coagulative necrosis
Neutrophilic infiltration
Infarct with yellow border

28
Q

What are the changes occurs on biopsy within 3-7 days of post MI?

A

Macrophage infiltration
Neutrophils infiltration decreases
Hyperemic borders

29
Q

What are the changes occurs on biopsy within 7-10 days of post MI?

A

Granulation tissue
Red brown margins
Depression in the scarred tissue

30
Q

What are the changes occurs on biopsy within 4-6 weeks of post MI?

A

Scar formation

White scar