Pastest Flashcards

1
Q

Signet cells and linitis plastica?

A

Adenocarcinoma

signet cells confirms a poorly differentiated adenocarcinoma

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2
Q

Carcinoid syndrome

A
Flush is the main symptom
Hypotension
Tachycardia
Right sided cardiac valve fibrosis
Increased skin temperature
PROFUSE secretory diarrhoea
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3
Q

Charcot’s triad

A
  • Fever
  • Jaundice
  • Abdominal pain

(acute cholangitis)

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4
Q

Spider naevie and hepatic disease?

A

True

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5
Q

Acanthosis nigricans and gastrointestinal malignancy?

A

True

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6
Q

Cutaneous pigmentation and Peutz-Jeghers syndrome?

A

True

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7
Q

Most common cause of GI haemorrhage?

A

Peptic ulcer disease

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8
Q

Can GI be a complication of overwhelming sepsis?

A

Stress ulcers causing severe GI bleeding are a recognised complication of severe burns and overwhelming sepsis

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9
Q

Causes of orogenital ulceration?

A
Behcets
Pemphigus and pemphigoid
Erythema multiforme
Reiter's syndrome
Herpes simplex virus
HIV
Syphilis
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10
Q

Prognostic indicators for acute pancreatitis?

A

Age over 55
Raised white count
Blood glucose
Urea
A fall in haemocrit and calcium and blood gas derangement
Amylase is not of prognostic value, it is only useful to make the inital diagnosis

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11
Q

Diptheria treatment?

A

Diptheria anti-toxin and penicillin/erythromycin

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12
Q

Nasal flaring. intercostal recession, increased respiratory effort and cyanosis are signs of what?

A

Respiratory distress

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13
Q

How might tracheo-oesophageal fistulae present?

A

May present immediately with an inability to feed

  • Chronic cough
  • pneumonia
  • cyanosed when feeding
  • failure to grow/thrive
  • when coughin, produces copious amounts of secretions and appear to “blow bubbles”
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14
Q

A 5 year old presents with a severe sore throat, drooling of saliva, high temperature and difficulty in breathing

A

The is the unforgettable clinical picture of acute epiglottitis

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15
Q

Breslow thickness?

A

The depth from the granular layer of the epidermis to the deepest melanoma cell
-The breslow thickness is a prognostic indicator

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16
Q

UVB, direct or inderect DNA damage?

A

UVB causes direct DNA damage

UVA causes indirect DNA damage

17
Q

Prognostic indicators which worsen the diagnosis of malignant melanoma?

A

Ulceration
Vascular invasion
Nodular subtype

18
Q

How do you investigate achalasia?

A

Oesophageal manometry

19
Q

Carcinoid syndrome flush is associated with what?

A

Tachycardia, hypotension and increased skin temperature

20
Q

Intermittent dysphagia could be caused by what

A

Benign oesophageal strictures

21
Q

Dukes A colon cancer

A

Confined to muscular lining of intestinal wall

22
Q

Dukes C colon cancer

A

Node involvement

23
Q

Dukes D colon cancer

A

Distant metastases are present

24
Q

Where does carcinoma of the stomach most commonly occur?

A

The pylorus

25
Q

Troisers sign?

A

Presence of a palpable lymph node in the left supraclavicular fossa, which is a sign of abdominal malignancy
-may be present in gastric cancers
(also called Virchows node)

26
Q

Absorption of what may be impaired after gastrectomy?

A

fat and fat soluble vitamins (D)

27
Q

Crypt abscesses

A

Ulcerative colitis (rare in Crohn’s)

28
Q

Rose thorn (deep) ulcers

A

Crohn’s disease

29
Q

Lymphod aggregates in Crohns or UC?

A

Crohns

30
Q

Dukes B colon cancer

A

Tumour extends across the bowel wall

31
Q

Causes of bright red PR bleeding?

A

Haemorrhoids or an anal fissure