Clinical rashes Flashcards
Chronic inflammatory disease of the pilosebaceous unit
Acne vulgaris
Mild acne
Scattered papules, pustules, comedones
Moderate acne
Numerous papules, pustules and mild atrophic scarring
Severe acne
Numerous papules, pustules, cysts, nodules, significant scarring
Acne treatment
Topical treatment:
Benzoyl peroxide – keratolytic, antibacterial
Topical vitamin A derivatives (retinoid): eg adapalene – drying effect
topical antibiotics – antibacterial and anti-inflammatory
Systemic treatment:
Antibiotics
Isotretinoin (oral retinoid) – effect on sebaceous gland activity. Lot of side effects including initial aggravation of acne.
Name a side effect of isotretinoin (used for acne)
Can initially aggravate acne
Difference between acne and roasacea
No comedones in rosacea
Factors exacerbating rosacea
Sudden change in temp, alcohol, spicy food
How to reduce aggravating factors in Rosacea?
Reduce dietary triggers, wear high factor sunscreen, avoid topical steroids
Antibiotics to use in Rosacea
TOPICAL metronidazole
Oral tetracycline long term
Isotretinoin low dose if severe
Telangiectasia : vascular laser
Rhinophyma: surgery/ laser shaving
Bullous pemphigoid and pemphigus vulgaris, which is deeper?
Bullous pemphigoid = DEJ
Pemphigus = superficial, intra-epidermal
What may be the initial presenting complaint in bullous pemphigoid?
itchy erythematous plaques and papules may be the presenting feature
Mucosal lesions in bullous pemphigoid?
Not likely
–> pemphigus vulgaris usually
Where would you develop bullous pemphigoid?
localized to one area, or widespread on the trunk and proximal limbs
Where would you get pemphigus vulgaris?
Typically affects scalp, face, axillae, groins
