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Prudent Use of Antimicrobials Entrance Exam > Past Questions 2021/ 2022 > Flashcards

Past Questions 2021/ 2022 Flashcards

1
Q

Enrofloxacin AMEG

A

B

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2
Q

Validity of a Vet Prescription

A

5 days

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3
Q

Gentamycin AMEG

A

C

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4
Q

How has AM consumption changed in the last 5 years in the EU

A

Decreased

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5
Q

Pharmacokinetics of colistin and gentamycin

A

Adsorption very low

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6
Q

O. Rhinotracheale frequently resistant AB

A

Tylosin and Difloxacin

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7
Q

Systemic T in Otitis Externa

A

Suppurative

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8
Q

This agent is effective against Actinobacillus suis and Mycoplasma hyopneumoniae in swine?

A

Enrofloxacin IM, Tulathromycin IM and Lincomycin-Spectinomycin combination IM

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9
Q

This drug can be used for the treatment of foot rot, as it is active against anaerobic bacteria and its penetration is good

A

Florefenicol + Lincomycin

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10
Q

This drug can effectively be used in cystitis in dogs if it’s caused by enterococci or lactamase producing E.
coli?

A

Amoxicillin clavulanic acid and Amoxicillin

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11
Q

Authorised for poultry and can be effective against fowl cholera

A

Amoxicillin

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12
Q

Authorised for poultry and can be effective against ulcerative enteritis

A

Phenoxymethylpencillin

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13
Q

Gamithromycin Admin

A

IM ONLY

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14
Q

1st line choice pharyngitis

A

Azithromycin

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15
Q

1st line choice canine pyoderma

A

Cefalexin

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16
Q

Systemic MRSP

A

Rifampicin

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17
Q

Polyserositis in Su

A

Strep. Suis

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18
Q

Pharmacokinetic

A

Cmax

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19
Q

Zinc Sulphate

A

IDD

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20
Q

Single Shot AB

A

BRDC

Respiratory dx

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21
Q

It is inevitable to remember the pharmacodynamic properties of certain antimicrobials to be able to reduce the spreading of resistance. Based on this knowledge macrolide antibiotics are advised to use in high dosages for short period of time.

A

False

FQ + aminoglycosides

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22
Q

Tulathromycin can reach effective concentration in lung and this concentration persist in lung until one week.

A

True

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23
Q

Enrofloxacin is excellent in the treatment of pneumonia caused by gram negative fastidious pathogens in swine, and it is outstanding activity against Mycoplasma species

A

True

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24
Q

Amoxicillin is authorised ONLY for intramuscular administration in both swine and cattle.

A

False

- IM and PO

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25
Q

As of February 2022, the prophylactic used of antimicrobials will be limited to the individual treatment of animals

A

False

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26
Q

The most common form of antibiotics used by veterinarians is a solution and premix

A

True

NOT INJECTION

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27
Q

The spread of antimicrobial resistance can be slowed down

A

True

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28
Q

From 2022, when antibiotics are added to feed, the duration of prophylactic treatment must not exceed two weeks

A

False

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29
Q

The efficacy of oral chlortetracycline against mycoplasmas in poultry species is uncertain due to poor absorption

A

True

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30
Q

In poultry species, Tilmicosin may be most effective in treating diseases caused by Spirochaete spp

A

False

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31
Q

Oral sulphonamide-trimethoprim combinations are particularly effective against mycoplasmas in poultry species

A

False

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32
Q

The PK/PD analysis is (AUC/MIC model) helps estimate the degree of spreading antimicrobial resistance. The higher the ratio the higher the chance is for selection of mutant bacteria resistant to the given antimicrobial agent

A

False

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33
Q

Acquired resistance to fluoroquinolone in pathogenic bacteria develops gradually and, in several stages, only after several weeks of treatment

A

False

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34
Q

There is a UTI infection in a GSD. From the urine sample E. Coli could be cultured, which has 32 𝞵g/ml MIC value to amoxicillin. Regarding the table, the substance will be effective during the treatment

A

GSD= True

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35
Q

There is a UTI infection in a shih-tzu dog. From the urine sample MRSA could be cultured, which has 64 𝞵g/ml MIC value to amikacin. Regarding to the table and PK/PD analysis, the substance will NOT be effective during the treatment

A

Shih-Tzu= True

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36
Q

There is a UTI infection in a 10-year-old Persian cat. From the urine sample E. Coli could be cultured, which has 4 𝞵g/ml MIC value to cefovecin. Regarding to the table and PK/PD analysis, the substance will be effective during the treatment

A

Persian Cat= False

37
Q

There is a UTI infection in a 4-year-old pug. From the urine sample Enterococcus faecalis could be cultured, which has 8 𝞵g/ml MIC value to doxycycline. Regarding to the table and PK/PD analysis, the substance will NOT be effective during the treatment

A

Pug= False

38
Q

It is proven, that animal products can transfer antimicrobial resistance to people, the most important and versatile vector of it is the E. coli

A

True

39
Q

In case of time dependent bactericidal antibiotics their maximum concentration should be at least six times higher in the treated compartment than the MIC volume of the given antibiotic agent for the given infectious bacterium isolate

A

False

40
Q

Multiple causes can be present in the background of BRDS, while the treatment of which the bacterial resistance is rare. Most of the empirically suitable antibiotics can treat the disease in case of P. Multocida, M. Haemolytica and M. Bovis infectious background as well

A

False

41
Q

In case of bovine P. Multocida respiratory disease the MIC value for ceftiofur is 0.004 mg/𝞵l. The concentration reached in the PELF, in the blood and in the pulmonary interstitial fluid is higher than the MIC value for more than 8 days. This means a correct drug choice for the treatment of the infectious disease

A

True

42
Q

In case of ruminant Porphyromonas levii interdigital dermatitis, although the substance can be present at the site of infection in high concentrations, using tetracycline locally is not advised due to the bacterial resistance against the substance

A

False

43
Q

The treatment of calf E. Coli diarrhoea depends on the severity of the animal, in case of lack of systemic symptoms the usage of antibiotic agents is not advised, fluid and electrolyte therapy are recommended

A

True

44
Q

For the treatment of Escherichia coli diarrhoea in weaned piglets, enrofloxacin is the best choice, taking into account pharmacokinetic, pharmacodynamic, antibiotic susceptibility and public health considerations

A

False

45
Q

Target receptor of amitraz

A

Ocotpamine Rc

46
Q

Topically for Canine Pyoderma

A

Neomycin

47
Q

Side Effects Florfenicol

A

NOT KCS/ Anaemia (Chloramphenicol SE)

48
Q

Using systemic treatment is not needed in cases of intertrigo, because bacteria cannot reach deeper part of the skin in this dx

A

Whole sentence is true

49
Q

General indication for AB

A

The product is indicated for several bacteria which are listed in the indication

50
Q

NOT Authorised for poultry in the EU

A

Chloramphenicol and Gentamycin

51
Q

Authorised for poultry in the EU

A

Tiamulin, Tylvalosin, phenoxymethylpenicillin

52
Q

Susceptibility testing should always be performed before treating folliculitis, because bacterial susceptibility is difficult to estimate in case of deep pyodermas

A

Whole Sentence is false

53
Q

This drug is very effective against fastidious bacteria and mycoplasmae as well and has excellent distribution.

A

Both= Enrofloxacin + tulathromycin

54
Q

True about foot dx in Ru

A

Interdigital dermatitis can be treated with tetracycline spray, because high, effective concentration can be reached with topical treatment at the site of infection

55
Q

This drug can be used for the treatment of foot rot, as it is active against anaerobic bacteria and its penetration is good

A

Tulathromycin

56
Q

Colistin Admin in Su

A

IM and PO

57
Q

In poultry E. coli can cause

A

Septicaemia + CRD

Also- granulomatosis + arthritis

58
Q

True about BRDC

A

Fastidious organisms are the most frequent bacteria present. Luckily,resistance is usually low in them to most antibiotics

59
Q

Lincomycin Admin in Su

A

PO and IM

60
Q

Amox + Clav in Su Admin

A

PO and IM

61
Q

Worst resistance rates

A

Poultry

62
Q

Brachyspira hyodsentry what antibiotic to use

A

Tylvalosin

63
Q

Amoxicillin can be used against Clostridia Perfringens C, E. Rhusiopathiae, Streptococcus

A

All 3

64
Q

Mastitis good general condition tx IMM infusion

A

True

65
Q

Plasmid E. coli strain in poultry

A

FALSE

Pigs

66
Q

As of February 2022, prophylaxis is not allowed to be used

A

False

67
Q

Ru, Fusobacterium Necrophorum, locally is good but systemic Tx with amox clav IV

A

False

- Lincomyin, Tulathromyin, Florfenicol

68
Q

High conc in macrophages

A

Macrolides

69
Q

Disc Diffusion methods something about cannot be used in PK/PD

A

Peforming AB susceptibility

70
Q

BRDC, M. bovis hard to eradicate and Tx, 3 drugs tulathromycin, gamithromycin, and enrofloxacin can be used for Tx?

A

True, all 3

71
Q

Florfenicol AMEG

A

C

72
Q

Marbofloxacin AMEG

A

B

73
Q

Colistin reduced by 95%

A

False

65%

74
Q

Use of FQ is prohibited in poultry

A

False

Resistant though

75
Q

Canine Pyoderma

A

Cefovecin + Amox/Clav

76
Q

Conc dependant bactericidal max conc should be 6x higher

A

False

8-10x

77
Q

Determine conc in pneumonia

A

All 3

PELF, blood plasma, urine

78
Q

E. coli in calves AB susceptibility, Faecal sample/ blood test if severe

A

True

79
Q

MRSA local

A

Mupirocin, Fusidic Acid

80
Q

MRSA systemic

A

Rifampicin, Amikacin, Florfenicol, Chloramphenicol

81
Q

Tylvasin

A

Macrolides

82
Q

Ceftiofur

A

3rd gen ceph, time dep bacter, inhibition cell wall synth

83
Q

Severe mastitis

A

IV FQ (marbo, enro), TTC, Pot. SA

84
Q

Colistin in poultry

A

Yes

85
Q

CIA drugs only in severe/ emergency

A

True, only to be used as a last resort

86
Q

Tx cow drying off no mastitis present

A

SCC is normal, Bismuth “seal” into teat canal with combo of disinfection

87
Q

“In PK/PD analysis for the treatment of respiratory infections, bacteria’s MIC value should be compared to the drug’s concentration in the…

A

All of them : Blood plasma, urine, PELF = pulmonary epithelial lining fluid

88
Q

Spaniel with ear infection and ruptured tympanic membrane

A

· Local + systemic treatment
· Gentamycin and polymyxin-B are ototoxic- CANNOT USE
· Orbifloxacin, marbofloxacin, florfenicol> can use in damaged TM

Prudent Use of Antimicrobials Entrance Exam (4 decks)

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