Past Questions 2021/ 2022 Flashcards
Enrofloxacin AMEG
B
Validity of a Vet Prescription
5 days
Gentamycin AMEG
C
How has AM consumption changed in the last 5 years in the EU
Decreased
Pharmacokinetics of colistin and gentamycin
Adsorption very low
O. Rhinotracheale frequently resistant AB
Tylosin and Difloxacin
Systemic T in Otitis Externa
Suppurative
This agent is effective against Actinobacillus suis and Mycoplasma hyopneumoniae in swine?
Enrofloxacin IM, Tulathromycin IM and Lincomycin-Spectinomycin combination IM
This drug can be used for the treatment of foot rot, as it is active against anaerobic bacteria and its penetration is good
Florefenicol + Lincomycin
This drug can effectively be used in cystitis in dogs if it’s caused by enterococci or lactamase producing E.
coli?
Amoxicillin clavulanic acid and Amoxicillin
Authorised for poultry and can be effective against fowl cholera
Amoxicillin
Authorised for poultry and can be effective against ulcerative enteritis
Phenoxymethylpencillin
Gamithromycin Admin
IM ONLY
1st line choice pharyngitis
Azithromycin
1st line choice canine pyoderma
Cefalexin
Systemic MRSP
Rifampicin
Polyserositis in Su
Strep. Suis
Pharmacokinetic
Cmax
Zinc Sulphate
IDD
Single Shot AB
BRDC
Respiratory dx
It is inevitable to remember the pharmacodynamic properties of certain antimicrobials to be able to reduce the spreading of resistance. Based on this knowledge macrolide antibiotics are advised to use in high dosages for short period of time.
False
FQ + aminoglycosides
Tulathromycin can reach effective concentration in lung and this concentration persist in lung until one week.
True
Enrofloxacin is excellent in the treatment of pneumonia caused by gram negative fastidious pathogens in swine, and it is outstanding activity against Mycoplasma species
True
Amoxicillin is authorised ONLY for intramuscular administration in both swine and cattle.
False
- IM and PO
As of February 2022, the prophylactic used of antimicrobials will be limited to the individual treatment of animals
False
The most common form of antibiotics used by veterinarians is a solution and premix
True
NOT INJECTION
The spread of antimicrobial resistance can be slowed down
True
From 2022, when antibiotics are added to feed, the duration of prophylactic treatment must not exceed two weeks
False
The efficacy of oral chlortetracycline against mycoplasmas in poultry species is uncertain due to poor absorption
True
In poultry species, Tilmicosin may be most effective in treating diseases caused by Spirochaete spp
False
Oral sulphonamide-trimethoprim combinations are particularly effective against mycoplasmas in poultry species
False
The PK/PD analysis is (AUC/MIC model) helps estimate the degree of spreading antimicrobial resistance. The higher the ratio the higher the chance is for selection of mutant bacteria resistant to the given antimicrobial agent
False
Acquired resistance to fluoroquinolone in pathogenic bacteria develops gradually and, in several stages, only after several weeks of treatment
False
There is a UTI infection in a GSD. From the urine sample E. Coli could be cultured, which has 32 𝞵g/ml MIC value to amoxicillin. Regarding the table, the substance will be effective during the treatment
GSD= True
There is a UTI infection in a shih-tzu dog. From the urine sample MRSA could be cultured, which has 64 𝞵g/ml MIC value to amikacin. Regarding to the table and PK/PD analysis, the substance will NOT be effective during the treatment
Shih-Tzu= True
There is a UTI infection in a 10-year-old Persian cat. From the urine sample E. Coli could be cultured, which has 4 𝞵g/ml MIC value to cefovecin. Regarding to the table and PK/PD analysis, the substance will be effective during the treatment
Persian Cat= False
There is a UTI infection in a 4-year-old pug. From the urine sample Enterococcus faecalis could be cultured, which has 8 𝞵g/ml MIC value to doxycycline. Regarding to the table and PK/PD analysis, the substance will NOT be effective during the treatment
Pug= False
It is proven, that animal products can transfer antimicrobial resistance to people, the most important and versatile vector of it is the E. coli
True
In case of time dependent bactericidal antibiotics their maximum concentration should be at least six times higher in the treated compartment than the MIC volume of the given antibiotic agent for the given infectious bacterium isolate
False
Multiple causes can be present in the background of BRDS, while the treatment of which the bacterial resistance is rare. Most of the empirically suitable antibiotics can treat the disease in case of P. Multocida, M. Haemolytica and M. Bovis infectious background as well
False
In case of bovine P. Multocida respiratory disease the MIC value for ceftiofur is 0.004 mg/𝞵l. The concentration reached in the PELF, in the blood and in the pulmonary interstitial fluid is higher than the MIC value for more than 8 days. This means a correct drug choice for the treatment of the infectious disease
True
In case of ruminant Porphyromonas levii interdigital dermatitis, although the substance can be present at the site of infection in high concentrations, using tetracycline locally is not advised due to the bacterial resistance against the substance
False
The treatment of calf E. Coli diarrhoea depends on the severity of the animal, in case of lack of systemic symptoms the usage of antibiotic agents is not advised, fluid and electrolyte therapy are recommended
True
For the treatment of Escherichia coli diarrhoea in weaned piglets, enrofloxacin is the best choice, taking into account pharmacokinetic, pharmacodynamic, antibiotic susceptibility and public health considerations
False
Target receptor of amitraz
Ocotpamine Rc
Topically for Canine Pyoderma
Neomycin
Side Effects Florfenicol
NOT KCS/ Anaemia (Chloramphenicol SE)
Using systemic treatment is not needed in cases of intertrigo, because bacteria cannot reach deeper part of the skin in this dx
Whole sentence is true
General indication for AB
The product is indicated for several bacteria which are listed in the indication
NOT Authorised for poultry in the EU
Chloramphenicol and Gentamycin
Authorised for poultry in the EU
Tiamulin, Tylvalosin, phenoxymethylpenicillin
Susceptibility testing should always be performed before treating folliculitis, because bacterial susceptibility is difficult to estimate in case of deep pyodermas
Whole Sentence is false
This drug is very effective against fastidious bacteria and mycoplasmae as well and has excellent distribution.
Both= Enrofloxacin + tulathromycin
True about foot dx in Ru
Interdigital dermatitis can be treated with tetracycline spray, because high, effective concentration can be reached with topical treatment at the site of infection
This drug can be used for the treatment of foot rot, as it is active against anaerobic bacteria and its penetration is good
Tulathromycin
Colistin Admin in Su
IM and PO
In poultry E. coli can cause
Septicaemia + CRD
Also- granulomatosis + arthritis
True about BRDC
Fastidious organisms are the most frequent bacteria present. Luckily,resistance is usually low in them to most antibiotics
Lincomycin Admin in Su
PO and IM
Amox + Clav in Su Admin
PO and IM
Worst resistance rates
Poultry
Brachyspira hyodsentry what antibiotic to use
Tylvalosin
Amoxicillin can be used against Clostridia Perfringens C, E. Rhusiopathiae, Streptococcus
All 3
Mastitis good general condition tx IMM infusion
True
Plasmid E. coli strain in poultry
FALSE
Pigs
As of February 2022, prophylaxis is not allowed to be used
False
Ru, Fusobacterium Necrophorum, locally is good but systemic Tx with amox clav IV
False
- Lincomyin, Tulathromyin, Florfenicol
High conc in macrophages
Macrolides
Disc Diffusion methods something about cannot be used in PK/PD
Peforming AB susceptibility
BRDC, M. bovis hard to eradicate and Tx, 3 drugs tulathromycin, gamithromycin, and enrofloxacin can be used for Tx?
True, all 3
Florfenicol AMEG
C
Marbofloxacin AMEG
B
Colistin reduced by 95%
False
65%
Use of FQ is prohibited in poultry
False
Resistant though
Canine Pyoderma
Cefovecin + Amox/Clav
Conc dependant bactericidal max conc should be 6x higher
False
8-10x
Determine conc in pneumonia
All 3
PELF, blood plasma, urine
E. coli in calves AB susceptibility, Faecal sample/ blood test if severe
True
MRSA local
Mupirocin, Fusidic Acid
MRSA systemic
Rifampicin, Amikacin, Florfenicol, Chloramphenicol
Tylvasin
Macrolides
Ceftiofur
3rd gen ceph, time dep bacter, inhibition cell wall synth
Severe mastitis
IV FQ (marbo, enro), TTC, Pot. SA
Colistin in poultry
Yes
CIA drugs only in severe/ emergency
True, only to be used as a last resort
Tx cow drying off no mastitis present
SCC is normal, Bismuth “seal” into teat canal with combo of disinfection
“In PK/PD analysis for the treatment of respiratory infections, bacteria’s MIC value should be compared to the drug’s concentration in the…
All of them : Blood plasma, urine, PELF = pulmonary epithelial lining fluid
Spaniel with ear infection and ruptured tympanic membrane
· Local + systemic treatment
· Gentamycin and polymyxin-B are ototoxic- CANNOT USE
· Orbifloxacin, marbofloxacin, florfenicol> can use in damaged TM
