Past Paper Qs 2 Flashcards

1
Q

Which of the following statements is true?
* Anaemia of inflammatory disease is characterized by low serum iron, low total iron binding capacity, high bone marrow iron, high percentage transferrin saturation
* Iron-deficiency anaemia is characterized by low serum iron, normal or high total iron-binding capacity, high bone marrow iron, low percentage transferrin saturatio
* Iron-deficiency anaemia is characterized by high serum iron, high bone marrow iron, high percentage transferrin saturation
* Anaemia of inflammatory disease is characterized by low serum iron, low bone marrow iron, low percentage transferrin saturation

A

Anaemia of inflammatory disease is characterized by low serum iron, low total iron binding capacity, high bone marrow iron, high percentage transferrin saturation

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2
Q

What are erythrocyte ghosts?

A

They are pale-staining empty cells on the blood film

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3
Q

What is diagnostic importance of RDW?

A

It describes the variability in red blood cells size and is expressed in %

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4
Q

What is prevalence?

A

It is an estimate of the frequency of a disease in a population at a point in time?

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5
Q

Acute leukaemia occurs..

A

when neoplastic transformation occurs at the stem/committed blast stage and the malignant cells have little differentiation potetial, proliferate rapidly and in uncontrolled manner. The clinical course is rapid and clinical signs are severe. Normal blood cell production is significantly reduced

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6
Q

Disseminated intravasculat coagulation (DIC) is characterized by an augmentation of normal clotting mechanisms which results in depletion of coagulation factors, deposition of fibrin clots in the microvasculature, the second activation of fibrinolytic mechanisms with the production of fibrin-degradation products (FDP) which have anticoagulant properties. There is pathophysiological paradox - ________ in the presence of haemorrhage

A

Thrombosis

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7
Q

Which of the following statements is true?
* Punctate reticulocyte has a clumped reticulum
* Punctate reticulocytes are more mature than aggregate reticulocytes in cat
* Punctate reticulocytes are younger than aggregate reticulocytes in cat
* The aggregate reticulosyt has 2-6 fine dots of residual RNA without clumping

A

Punctate reticulocytes are more mature than aggregate reticulocytes in cat

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8
Q

The longest life span of red blood cells is in?

A

Reptiles

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9
Q

Interprete following laboratory findings together - normal or low packed cell volume with high plasma protein

A

Hyperglobulinemia

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10
Q

What is polychromatic cell?

A

It is young red blood cell

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11
Q

A major blood-forming organ in bony fish is?

A

the kidney

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12
Q

Von Willebrand factor (VWF) is needed for?

A

The adherence of the platelet to the subendothelial surface of an injured vessel and also contributes to platelet aggregation. It stabilizes coagulation factor VIII

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13
Q

What are schisocytes and what is their diagnostic importance?

A

RBC fragments; vascular neoplasms (e.g., haemoangiosarcoma), DIC, iron deficiency

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14
Q

Which of the following statements is true?
* Regenerative left shift occurs when the storage pool is depleted and there is demand for neutrophils, which is met by the release of immature neutrophils or even metamyelocytes and earlier precursors from the maturation pool
* Acute leukaemia occurs when the neoplastic transformation occurs in either a stem cells or later cell but progeny retain a strong tendency to differentiate, the cells are morphologically well differentiated but are functionally abnormal
* In a degenerative left shift there is a low or normal RBC count and band neutrophils exceeds mature neutrophils exceeds mature neutrophils
* Left shift occurs when increased band neutrophils, neutrophilia in which mature neutrophils exceeds band

A

In a degenerative left shift there is a low or normal RBC count and band neutrophils exceeds mature neutrophils exceeds mature neutrophils

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15
Q

Nucleated platelets (thrombocytes) are not present on blood films of?

A

Mammals

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