past paper errors

Question 1

Gentamicin: interpreting the graph.

What to do if:

• Low peak?
• High peak?
• Low trough?
• High trough

Answer 1

Peak:
If high- lower the dose
If low- increase the dose

Trough:
If high- increase the dosage interval
If low- decrease the dosage interval

Question 2

Isotretinoin

Monitoring points

SE?

Answer 2

Monitor hepatic (liver) function and LIPIDS at baseline , one month after starting and 3 monthly.

SE:
Alopecia,
anaemia
neutropenia/ thrombocyopenia
hyperuricaemia(risk of pancreatitis if tryglycerides above 9mmol/l)
photosensitivity.

Question 3

symptoms of hyperthyroidism

Answer 3

Cold intolerance
trembling hands
weight loss
depression memory problems

Question 4

co-amoxiclav risk?

Answer 4

cholestatic jaundice (increased ALK and GGT)

Question 5

medicines which cause QT prolongation

Answer 5

antiarrhythmics- amiodarone
antimicrobials
antidepressants
antipsychotics

Question 6

permethrin

where to apply and for how long

Answer 6

8-12 hours

suitable for adults, children aged 2 months and older and the elderly.

adult- not on face
BUT
<2 years old/ elderly- apply to the face( neck, face, ears, scalp)

Question 7

Drugs to stop in the peri-operative period

Answer 7

clopidogrel- 7/7 before
-omit 
-ACE-I/ARB on the morning off surgery
-lithium
diabetic meds
-COC/HRT