learning from mistakes Flashcards

1
Q

Interaction with Allopurinol

can allopurinol be used in renal imapirment?

A

azathioprine(increased effect of azathioprine)

Yes!

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2
Q

AID- risk of pneumonia- what med is used for prophylaxis

A

Co-trimoxazole

Atovaquone is C/I

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3
Q

fludrocortisone electrolyte disctubance

what to avoid with

A

hypokalaemia

methadone- risk of QT/Torsades de pointes

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4
Q

colestyramine timins with food

A

1 hour before 4 hour after

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5
Q

GTN tabs - how long do they provide symptomatic relief?

A

30 min

NO COTTON WOOL

DISCARD AFTER 8 WEEKS

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6
Q

H pylori Tx

A

clarithromycin
Amoxicillin
PPI

if Pen allergic- metronidazole.

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7
Q

Loperamide- max tabs/day

A

8 Tabs/day (16mg)

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8
Q

Colchicine max G/ course

Time between courses

A

6g

3 days between acute courses

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9
Q

perindopril dose timing

A

30-60 min before food

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10
Q

bendroflumethiazide SE

A
  • hypokalaemia
  • hyperglycaemia
  • hypercalcaemia
  • herperuricaemia
  • hyponatraemia
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11
Q

high intensity statin

A

Atorva 20 -YES

Simva 40- NO

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12
Q

metronidazole gel + warfarin

A

Increased INR

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13
Q

Aminophylline- effect on potassium

A

HYPOKALAEMIA

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14
Q

Prostaglandin analogues- counselling

A

Brown pigmentation

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15
Q

Filgrastim- indication

A

NEUTROPENIA

Commonly used in chemo as it increases production of neutrophils

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16
Q

pregnancy- which vit is advised to take at a dose of 10mcg/day

A

D

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17
Q

why do we need vit D

A

To absorb calcium

in renal impairment- use activated form (calcitrol)

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18
Q

levothyroxine dose timing

A

morning, 30 min before breaky/ caffeine.

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19
Q

what is Oligouria

A

low vol urine

symptom of AKI

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20
Q

Linezolid- monitoring

A

OPTIC NEUROPATHY(visual disturbance)

FBC

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21
Q

Risk of long term trimethoprim

A

blood disorders

watch out for mouth ulcers etc

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22
Q

isotretinoins- avoid which vitamin

A

VIT A

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23
Q

first line tx for chronic stable plaque psoriasis

A

coal tar

24
Q

why are ACE- I cautioned in diabetes

A

lower glucose

25
Q

lethal comp of anaesthesia

A

malignant hyperthermia

26
Q

chemo- highly emetogenic

A

cisplatin

cyclophosphamide

27
Q

least emetogenic

A

vincristine

28
Q

vincristine SE

A

hair loss

29
Q

clindamycin- diarrhoea

A

stop

antibiotic associated colitis

30
Q

macrolides- nausea

A

normal

31
Q

MHRA Quinine

A

QT

32
Q

isotretinoin- giving blood

A

avoid

and for 1 month after

33
Q

threadworms- effect on children

A

Bed wetting

waking at night

34
Q

antipsychotic weight gain

A

olanzapine
clozapine
quetiapine

35
Q

dithranol (for psoriasis)

A

staining

36
Q

CD -patient returns

A

denature prior to disposal

authorised witness not required.

37
Q

purpuric skin rash- which AED

A

phenytoin

38
Q

HF- Diuretic

A

NOT K sparing

furosemide best

39
Q

growth hormones schedual

A

CD 4 part 2

40
Q

baclofen ( should they be taken with ACE/B-Blocker?)

A

NO

Increases hypotensive effect

41
Q

Ganciclovir. when C/I

A

Low neut count

42
Q

bromocriptine (suppression of lactation)- risk when started

A

hypotensive reaction

43
Q

febuxostat

A

tx of gout

prophylaxis and acute episodes

SJS

44
Q

what schedual is midazolam

A

3

45
Q

methotrexate and trimethoprim

A

avoid

46
Q

what is in malarone?

when to take

A

proguanil/atovaquone

1-2 days before
during
1 week after

47
Q

lithium- how oftern to monitor LFTs

A

every 6 months

48
Q

sodium valproate

A

hepatotoxicity

pancreatitis.

49
Q

which drugs carry as risk of gingival hyperplasia?

A

ciclosporin
phenytoin
nifedipine

50
Q

which drugs increase saliva production

A

clozapine

neostigmine (anticholinesterase)

51
Q

which affect can phenobarb have on an infants

A

inhibits sucking reflex

52
Q

lorazepam schedual

A

cd4

Lorazepam

53
Q

antimilarial to avoid in renal impairment

A

proguanil

54
Q

reversal agent for heparin toxicity

A

protamine sulphate

55
Q

which anti-diabetic should NOT be stopped during surgery

A

SGLT2- risk of DKA

56
Q

is a date legal req for a CD requisition

A

no

57
Q

sumatriptan and ssris- whats the risk

A

serotonin syndrome