Passmedicine Flashcards

1
Q

what type of urinary incontinence is the most associated with amitriptyline(TCAs)?

A

overflow incontinence - anticholinergic effect

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2
Q

what are the common side effects of TCAs? (6)

A
drowsiness 
dry mouth 
blurred vision 
constipation 
urinary retention 
lengthening of QT interval
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3
Q

what are the more sedative TCAs? (4)

A

amitriptyline
clomipramine
dosulepin
trazodone

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4
Q

what are the less sedative TCAs (3)?

A

imipramine
lofepramine
nortriptyline

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5
Q

What is raised in anorexia? (G’s and C’s)

A

growth hormone, glucose, salivary glands, cortisol, cholesterol, cartinaemia

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6
Q

what is the name of the condition when a person believes a famous person is in love with them?

A

Erotomania (De Clerambault’s syndrome)

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7
Q

what is the cause of a suicide attempt being successful?

A

male gender
previous suicide attempts
white ethnicity, increasing age
previous mental illness such as depression

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8
Q

what is not a first rank symptom of schizophrenia?

A

catatonia

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9
Q

what is the duration that symptoms to be present before a diagnosis of PTSD?

A

1 month

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10
Q

how can concordance with antipsychotics be improved?

A

with depot medication

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11
Q

what is a common side effect of anti-psychotics?

A

parkinsonian symptoms

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12
Q

which gender does antisocial personality affect more?

A

male gender

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13
Q

what is stopping of voluntary movement or stay still in an unusual position?

A

catatonia

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14
Q

what class of medication should be avoided in patients taking SSRIs?

A

triptans

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15
Q

what happens if you prescribe NSAIDs with SSRIs?

A

prescribe PPI along with it

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16
Q

If on warfarin /heparin should you avoid SSRIs?

A

yes and consider mirtazapine

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17
Q

why should you avoid MAOIs and SSRIs?

A

increased risk of serotonin syndrome

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18
Q

when stopping a SSRI the dose should gradually reduced over what time period?

A

4 week

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19
Q

Use of SSRIs in the first trimester gives a small increased risk of?

A

congenital heart defects

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20
Q

use of SSRIs in the third trimester can result in?

A

persistent pulmonary hypertension of the newborn

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21
Q

which SSRI has an increased risk of congenital malformation particularly in the 1st trimester?

A

paroxetine

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22
Q

what is the first line treatment for children and young people with anorexia nervosa?

A

family based therapy

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23
Q

what is the second line treatment for children and young people with anorexia nervosa?

A

CBT

24
Q

what is the first line treatment for adults with anorexia nervosa?

A

ndividual eating-disorder-focused cognitive behavioural therapy (CBT-ED)

  • Maudsley Anorexia Nervosa Treatment for Adults (MANTRA)
  • specialist supportive clinical management (SSCM)
25
Q

what is used to treat moderate/severe tragic dyskinesia?

A

tetrabenazine

26
Q

what is used to treat acute dystonia?

A

procyclidine and benzotropine

27
Q

what is the ICD10 criteria for duration of depressive illness?

A

2 weeks

28
Q

antipsychotics in the elderly cause an increased risk of?

A

stroke and VTE

29
Q

What is the name of a syndrome where you purposefully cause symptoms?

A

munchaesen’s syndrome

30
Q

what syndrome presents with loss of function which is non-physical eg. memory?

A

dissociative disorder

31
Q

which syndrome presents with loss of function with no cause?

A

conversion syndrome

32
Q

what does zopiclone increase the risk of?

A

falls in elderly patients

33
Q

what enhance the effect of BAGA, the main inhibitory neurotransmitter?

A

Benzodiazepines

34
Q

what is a short term side effect of ECT?

A

cardiac arrhythmia

35
Q

what is a sustained muscle contraction?

A

acute dystonia

36
Q

what is the 1st line management for PTSD that has lasted more than 1month?

A

trauma focused CBT or EMDR

37
Q

what is the strongest risk factor for psychotic disorders?

A

family history

38
Q

what is associated with random panic attacks on a background of no anxiety usually?

A

panic disorder

39
Q

what is associated with anxiety in situations where escape is difficult or help unavailable?

A

agoraphobia

40
Q

what is persistent free floating anxiety with associated features?

A

GAD

41
Q

what is the key difference between knight’s move and flight of ideas?

A

knight’s move thinking there are illogical leaps from one idea to another whereas flight of ideas there are discernible links between ideas

42
Q

what is new word formations?

A

neologisms

43
Q

when speech is completely incoherent and words are strung together into sentences that do not make sense?

A

word salad

44
Q

what is it called when ideas are related to each other only by the fact that they sound similar?

A

clang associations

45
Q

what is the syndrome when symptoms last more than three months after the initial injury. They are often non-specific neurological symptoms and the initial injury is often trivial and can be overlooked - history of contract sports?

A

post-concussion syndrome

46
Q

delirium tremens - alcohol withdrawal for?

A

72 hours

47
Q

seizures - alcohol withdrawal for?

A

36 hours

48
Q

symptoms - alcohol withdrawal for?

A

6-12 hours

49
Q

clozapine missed for more than 48 hours?

A

dose should be restarted again slowly

50
Q

what class of psychiatric drugs are associated with hyponatraemia?

A

SSRIs

51
Q

what should be considered in an elderly patient with first episode sudden onset psychosis?

A

CT head - organic cause for their presentation

52
Q

which antidepressant can be prescribe due to useful side effects of sedation and increased appetite?

A

mirtazapine

53
Q

what is the most common side effect of clozapine?

A

constipation/intestinal obstruction

54
Q

what antipsychotic is best suited for prolactin elevation?

A

aripiprazole

55
Q

what is a sense of inner restlessness and ability to keep still?

A

akathisia