Passmed PSA Flashcards
Which of the following is contraindicated in patients with structural heart disease?
Amiodarone Digoxin Bisoprolol Flecainide Warfarin
Flecainide
Which drugs might worsen seizure control in epilepsy patients?
Alcohol
Ciprofloxacin
Aminophylline
Methylphenidate
Which antidiabetic medications are contraindicated in patients with heart failure?
Pioglitazone
How are patients on warfarin managed during pregnancy?
Usually switched to LMWH
Which analgesics are contraindicated in HF patients?
NSAIDs (cause fluid retention)
Why is verapamil contraindicated in heart failure?
Negative inotropic effect
Which medications are known to exacerbate psoriasis?
Beta blockers
Lithium
Antimalarials
NSAIDs/ACEi
Which drugs are contraindicated in asthma?
B-blockers
NSAIDs
Adenosine
What proportion of asthma patients are sensitive to NSAIDs?
10-20%
What feature of an asthmatic increases the likelihood that they will experience NSAID induced bronchospasm?
Nasal polyps
WHat should you do if trough drug levels are too high?
Increase duration between doses (e.g. TDS to BD)
Is HRT safe for use in IHD?
No
When should you consider lowering the dose of Levothyroxine given to a hypothyroid patient?
When the TSH is low, indicating over replacement
What type of insulin is Determir?
Long acting
Which frequently used anti-diabetic commonly causes hypos?
Gliclazide
Why should patients on bisphosphonates regularly see their dentist?
Risk of osteonecrosis of the jaw
What should you prescribe someone with angina?
Atorva 80
Diltiazem MR
Are psychiatric problems associated with long or short term steroid use?
Long term
WHat effect do beta blockers have on glucose control?
Impair hypoglycaemic awareness
What effect does metformin have on INR in warfarin patients?
Increases it
What electrolyte abnormality do sulphonylureas such as glimepiride cause/
Hyponatraemia (SIADH)
What effect does liver dissae have on INR?
Increases due to impaired vitamin K synthesis
In what clinical scenario should 15L non rebreathe oxygen be given regardless of SpO2?
Anaphylaxis
How much O2 should be given to a COPD patient without blood gas analysis?
28% Venturi at 4l/min
