Passmed PSA Flashcards

1
Q

Which of the following is contraindicated in patients with structural heart disease?

Amiodarone
Digoxin
Bisoprolol
Flecainide
Warfarin
A

Flecainide

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2
Q

Which drugs might worsen seizure control in epilepsy patients?

A

Alcohol
Ciprofloxacin
Aminophylline
Methylphenidate

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3
Q

Which antidiabetic medications are contraindicated in patients with heart failure?

A

Pioglitazone

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4
Q

How are patients on warfarin managed during pregnancy?

A

Usually switched to LMWH

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5
Q

Which analgesics are contraindicated in HF patients?

A

NSAIDs (cause fluid retention)

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6
Q

Why is verapamil contraindicated in heart failure?

A

Negative inotropic effect

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7
Q

Which medications are known to exacerbate psoriasis?

A

Beta blockers
Lithium
Antimalarials
NSAIDs/ACEi

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8
Q

Which drugs are contraindicated in asthma?

A

B-blockers
NSAIDs
Adenosine

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9
Q

What proportion of asthma patients are sensitive to NSAIDs?

A

10-20%

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10
Q

What feature of an asthmatic increases the likelihood that they will experience NSAID induced bronchospasm?

A

Nasal polyps

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11
Q

WHat should you do if trough drug levels are too high?

A

Increase duration between doses (e.g. TDS to BD)

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12
Q

Is HRT safe for use in IHD?

A

No

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13
Q

When should you consider lowering the dose of Levothyroxine given to a hypothyroid patient?

A

When the TSH is low, indicating over replacement

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14
Q

What type of insulin is Determir?

A

Long acting

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15
Q

Which frequently used anti-diabetic commonly causes hypos?

A

Gliclazide

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16
Q

Why should patients on bisphosphonates regularly see their dentist?

A

Risk of osteonecrosis of the jaw

17
Q

What should you prescribe someone with angina?

A

Atorva 80

Diltiazem MR

18
Q

Are psychiatric problems associated with long or short term steroid use?

A

Long term

19
Q

WHat effect do beta blockers have on glucose control?

A

Impair hypoglycaemic awareness

20
Q

What effect does metformin have on INR in warfarin patients?

A

Increases it

21
Q

What electrolyte abnormality do sulphonylureas such as glimepiride cause/

A

Hyponatraemia (SIADH)

22
Q

What effect does liver dissae have on INR?

A

Increases due to impaired vitamin K synthesis

23
Q

In what clinical scenario should 15L non rebreathe oxygen be given regardless of SpO2?

A

Anaphylaxis

24
Q

How much O2 should be given to a COPD patient without blood gas analysis?

A

28% Venturi at 4l/min