pass med y1-3 Flashcards
sulfonylureas MOA
bind to an ATP-dependent K+(KATP) channel on the cell membrane of pancreatic beta cells
renal failure following transplant in otherwise well patient
delayed graft function
where is the most ACE in the body
lungs
what is important to check after someone has been stuck after a fall
creatine kinase
diabetic drug with low risk of hypoglycaemia and causes glycosuria
SGLT-2 inhibitors
sitagliptin (DPP-4 inhibitor) MOA
increase levels of incretins such as GLP-1 and GIP
by reducing their peripheral breakdown
hormone increasing appetite
ghrelin
most commone substance causing renal stones
calcium oxalate
hyperkalaemia on ecg
small p waves, tall, tented T waves, prolonged PR interval, and bradycardia
graves pathophysiology
IgG antibodies are formed against the TSH receptors on the thyroid gland
where does obturator nerve exit pelvis
obturator foramen
what is enlarged in bph
median lobe
reduced ankle jerk- what nerve root
S1
what secretes secretin
mucosal cells in the duodenum and jejunum
non-patholgys that can raise PSA
digital rectal exam, ejaculation, vigorous excerise
medications to be stopped in AKI
NSAIDS (not aspirin if cardioprotective dose), aminoglycosides (eg gentamicin), ACEi, ARBs, diuretics
hypocalciaemic patient not responding to calcium supplementation (or vit d)
Hypomagnesaemia
testicular cancer causing gynocomastia
HCG secreting teritoma
side effect of acutane (oral isotretinion)
photosensitivity
gout aspirate
needle-shaped negatively birefringent monosodium urate crystals
Structures in the carpal tunnel
Flexor digitorum profundus (four tendons)
Flexor digitorum superficialis (four tendons)
Flexor pollicis longus
Median nerve