Parvovirus

Question 1

What are the smallest DNA animal viruses?

Answer 1

Parvoviruses

Question 2

viral replication of parvovirus is dependent on?

Answer 2

dependent on functions supplied by replicating host cells or by coinfecting helper viruses.

Question 3

Parvovirus has tropism for ?

Answer 3

Tropism for erythroid progenitor cells

Question 4

Parvovirus can be inactivated by?

Answer 4

formalin, β-propiolactone, and oxidizing agent

Question 5

Dependovirus

Answer 5

The genus Dependovirus contains members that are defective and depend on a helper virus (an adenovirus or herpesvirus) for replication.

Question 6

What. Is The cellular receptor for B19?

Answer 6

blood group P antigen (globoside).

The α5β1 integrin is believed to be a coreceptor for B19 entry.

Question 7

Learn the important properties of parvovirus

Answer 7

Check text book

Question 8

Blood sample features of Erythema Infectiosum (Fifth Disease)

Answer 8

The first episode of illness coincides in time with viremia and reticulocytopenia and with detection of circulating IgM–parvovirus immune complexes.

Specific IgG antibodies appear about 15 days postinfection.

Question 9

Available tests are for human bocavirus include

Answer 9

polymerase chain reaction (PCR), probe hybridization of serum or tissue extracts, and in situ hybridization of fixed tissue.

Question 10

B19 DNA has been detected in what body samples?

Answer 10

serum, 
blood cells, 
tissue samples, and respiratory secretions
Saliva
Stool sample

Question 11

Antibody for B19 develops when?

Answer 11

Between age 5 to 19