Partial & Total Laryngectomy/Tumors-Test 2 Flashcards
Tumors of the larynx can be divided into ____ & ___ tumors
benign; malignant
Intrinsic cancer
Tumor developing on the true vocal cord (if it’s inside cartilage)
Extrinsic cancer
Tumor developing in some other part of the larynx
Leukoplakia
White growth that if not treated can develop into cancer
Tumor definition
Abnormal mass of tissue
Etiology of benign tumors
Unknown
Believed that most are the result of a chronic inflammatory response
When can a Benign tumor occur?
At any age
Most occur in the 35-50 age range, with 70% occurring in males & 30% occurring in females
Where do Benign tumors most often occur?
Most frequently on the vocal cords & most are located on the anterior 1/3 of the cord with the least being found on the posterior 1/3
Most common symptom of benign laryngeal tumors
Hoarseness
Who gets cancer of the larynx
Middle-aged or older men or women with a history of smoking
Predisposition factors to laryngeal cancer
Pt factors: excess alcohol & tobacco consumption, presence of a chronic disease state
Who is more likely to get laryngeal cancer?
Ratio of men to women is 7:1
Women are getting it more often due to increasing #s of women smoking, especially in Europe
Most common sx of Laryngeal Cancer
Hoarseness
If cancer is intrinsic, hoarseness is an early symptom
Prognosis for intrinsic laryngeal cancer:
Better than any other site of body since surgical removal of organ is considered a cure
Sx’s and Extrinsic Laryngeal Cancer
Does not produce early symptoms because it does not interfere with the voice
Most serious symptom is dyspnea
Might have problems with breathing
Locations of Laryngeal Tumors
May occur at 3 sites:
Glottic (on VFs/larynx), supraglottic, subglottic
Glottic carcinoma
Most common type of laryngeal cancer
Initial symptom of glottic carcinoma
Hoarseness
If it goes undetected & grows to large proportion, laryngeal stridor occurs & airway will become obstructed
Supraglottic Carcinoma
Occurs in the pyriform sinuses, the false VFs or ventricular bands, the ventricles, & the aryepiglottic folds
Initial symptoms of Supraglottic Carcinoma
Dysphagia accompanied by pain radiating to ear on speaking and swallowing
Subglottic Carcinoma
Develops on the undersurface of the VFs
Initial symptoms of Subglottic Carcinoma
Difficulty with breathing
Tumor Stages
TNM System
T: primary tumor
N: regional lymph nodes
M: distant metastasis
TNM: T:
T: Primary tumor
- Supraglottis
- Glottis
- Subglottis
T1s Lesion
Pre-invasive carcinoma or a carcinoma in situ (carcinoma encapsulated & hasn’t broken out of basal membrane)
Rarely found
Can be locally excised when found
Carcinoma in Situ
Can arise in any part of larynx, but majority occur on true VFs
Lesion is composed of squamous cells
Initial change in this tumor occurs in basal layer of epithelium
Important feature is that neoplastic cells are always confined by basement membrane
Lesion never becomes submucosal
Will usually progress into an invasive cancer through violation of basement membrane
Supraglottis Tumor Stages:
T1s: Carcinoma in Situ
T1: Tumor limited to region with normal mobility of structures
T2: Tumor of epiglottis &/or ventricles or ventricular bands & extending to vocal cords without fixation
T3: Tumor limited to larynx w/ fixation &/or destruction or other evidence of deep invasion
T4: Tumor with direct extension beyond larynx, to pyriform sinuses, post-cricoid region, vallecula, or base of tongue
Going posteriorly & upward
Glottis Tumor Stages:
T1s: Carcinoma in Situ
T1: Tumor limited to region with normal mobility
T2: Tumor extending to either the subglottic or supraglottic region w/ normal or impaired mobility
T3: Tumor limited to larynx w/ fixation of 1 or both cords
T4: Tumor extending beyond larynx into cartilage, pyriform sinus, post-cricoid region, or skin
Subglottis Tumor Stages:
T1s: Carcinoma in Situ
T1: Tumor limited to region with normal mobility
T2: Tumor involving subglottic region & extending to 1 or both cords
T3: Tumor limited to larynx w/ fixation of 1 or both cords
T4: Tumor extending beyond larynx to post-cricoid region, trachea, or skin
Tumor Stages: Lymph Nodes
N: Regional lymph nodes N0: Regional lymph nodes not palpable N1: Movable homolateral nodes N2: Movable contralateral or bilateral nodes N3: Fixed nodes