Parte2 -1 Flashcards

1
Q

4 vertices dos dominios

A
  • All Beta
  • All Alpha
  • Alpha + Beta
  • Alpha / Beta
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2
Q

All Beta

A

Predominam folhas Beta

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3
Q

All Alpha

A

Predominam helices alpha

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4
Q

Alpha + Beta

A

Existem tanto de folhas Beta como de helices Alpha

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5
Q

Alpha / Beta

A

Existem folhas Beta alternadas com helices Alpha

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6
Q

Problemas do Folding de Proteínas - 1958

A

Primeira estrutura tridimensional

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7
Q

Problemas do Folding de Proteínas - 1961

A

Hipótese termodinâmica

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8
Q

Problemas do Folding de Proteínas - 1968

A

Paradoxo de Levinthal

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9
Q

Paradoxo de Levinthal

A

Proteína podem apresentar vias cinéticas preferenciais (funil de energia- passam de unfolded para folded)

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10
Q

Hipótese termódinamica

A

Gradiente de energia livre leva a ocorrer folding

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