part 7 MH meds Flashcards
Blocks neuronal reuptake of two monoamine transmitters: NE and 5-HT (serotonin). These increase the concentration of these transmitters at CNS synapses and intensify their effects.
TCA’s
What are TCA’s used for?
depression
bipolar
fibromyalgia
What are the AE of TCA’s?
orthostatic hypotension anticholinergic effects diaphoresis sedation cardiac toxicity seizures hypomania suicide risk
What is the most hazardous of the antidepressants?
MAOI’s
What is MAO?
enzyme found in the liver
What is MOA of MAOI’s?
inhibits MAO
What are the therapeutic uses of MAOI’s?
depression
other psychiatric disorders (bulimia, agoraphobia)
What are the AE’s of MAOI’s?
CNS stimulation
ortho hypotension
HTN crisis for tyramine
What is an atypical antidepressant?
Bupropion (Wellbutrin)
What are the classes of antidepressant drugs?
- TCAs
- SSRIs
- SNRIs
- serotonin norepinephrine disinhibitor
- MAOIs