part 7 MH meds Flashcards

1
Q

Blocks neuronal reuptake of two monoamine transmitters: NE and 5-HT (serotonin). These increase the concentration of these transmitters at CNS synapses and intensify their effects.

A

TCA’s

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2
Q

What are TCA’s used for?

A

depression
bipolar
fibromyalgia

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3
Q

What are the AE of TCA’s?

A
orthostatic hypotension 
anticholinergic effects 
diaphoresis 
sedation 
cardiac toxicity 
seizures 
hypomania 
suicide risk
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4
Q

What is the most hazardous of the antidepressants?

A

MAOI’s

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5
Q

What is MAO?

A

enzyme found in the liver

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6
Q

What is MOA of MAOI’s?

A

inhibits MAO

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7
Q

What are the therapeutic uses of MAOI’s?

A

depression

other psychiatric disorders (bulimia, agoraphobia)

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8
Q

What are the AE’s of MAOI’s?

A

CNS stimulation
ortho hypotension
HTN crisis for tyramine

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9
Q

What is an atypical antidepressant?

A

Bupropion (Wellbutrin)

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10
Q

What are the classes of antidepressant drugs?

A
  • TCAs
  • SSRIs
  • SNRIs
  • serotonin norepinephrine disinhibitor
  • MAOIs
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