part 2 Flashcards
MANAGEMENT OF INFERTILITY
- CONTROLLED OVARIAN STIMULATION WITH INTRAUTERINE
INSEMINATION (ARTIFICIAL INSEMINATION) - ASSISTED REPRODUCTIVE TECHNIQUES
- Agent for ovulation induction
CONTROLLED OVARIAN STIMULATION
– First line treatment for those with anovulation and sufficient ovarian estrogen production
- Given only in patients with intact hypothalamic-pituitary ovarian
axis
Clomiphene citrate
No dominant follicle after administration
* Taking _________does not guarantee follicle formation. Follicle monitoring is important
Clomiphene Resistance
Risk of Ovulation Induction:
1.) Multiple Pregnancy
2.) More common with the use of Gonadotropins (FSH)
3.)Life-threatening – When all follicles rupture at the same time
1.) 5-8% with Clomiphene
2.) Ovarian Hyperstimulation Syndrome
3.) ASCITES and EFFUSION
- It is the deliberate introduction of
sperm into the uterine cavity for the
purpose of achieving a pregnancy
through in vivo fertilization (inside
the body) by means other than
sexual intercourse
INTRAUTERINE INSEMINATION
- Second-line treatment for unexplained infertility
Ideal treatment for endometriosis because it is a
progressive disease
- Ovulatory dysfunction
- Failed ovulation induction alone
- Male Subfertility
INTRAUTERINE INSEMINATION
INTRAUTERINE INSEMINATION
- A failure of ____times of ovulation induction warrants intrauterine insemination
6
- Refers to all techniques involving direct retrieval of oocyte from the ovary
- Involves manipulation of the oocyte
ASSISTED REPRODUCTIVE TECHNOLOGIES
ASSISTED REPRODUCTIVE TECHNOLOGIES INDICATIONS
- Severe or bipolar tubal disease
- Severe endometriosis
- Women >35 y/o with 6 months of failed infertility treatment
- Third line treatment for those with unexplained infertility and
ovulatory dysfunction - When other treatments have failed
ASSISTED REPRODUCTIVE TECHNOLOGIES PROCEDURES
- IN VITRO FERTILIZATION
- GAMETE INTRAFALLOPIAN TRANSFER (GIFT)
- ZYGOTE INTRAFALLOPIAN TRANSFER (ZIT)
- TUBAL EMBRYO TRANSFER (TET)
- PERITONEAL OOCYTE AND SPERM TRANSFER (POST)
- According to the Catechism of the Catholic Church, techniques
involving only the married couple (homologous artificial insemination and fertilization) are perhaps less reprehensible, yet remain morally unacceptable since they dissociate the sexual act from the procreative act
ETHICAL ISSUE
- Practice in which a woman (the surrogate mother) bears a child for a couple unable to produce children in the usual way, usually, because the wife is infertile or otherwise unable to undergo pregnancy
SURROGATE MOTHERHOOD
1.) The surrogate mother is impregnated through artificial
insemination with the sperm of the husband
2.) The wife’s ova and the husband’s sperm are subjected to in vitro fertilization and the resulting embryo is implanted in the surrogate mother
1.) TRADITIONAL SURROGACY
2.) GESTATIONAL SURROGACY
In both traditional and gestational surrogacy, the surrogate gives up all ____________, but this has been subject to legal challenge
parental rights
- The stress, anxiety, and emotional distress the surrogate mother has
- The emotional bond between the biological mother and child is
extremely strong and that surrogate motherhood is unnatural and immoral because it violently breaks that bond
ETHICAL ISSUES SURROGATE
LEGITIMACY AND CRITERIA OF THERAPEUTIC PROCEDURES OF HUMAN EMBRYO
- Strictly therapeutic
- Explicit objective is health maladies (chromosomal defects)
- Directed to the true promotion of the personal well-being of an individual
- Does not harm the integrity of the embryo
- Does not worsen the embryo’s condition of life
- Delicate and precaution in embryonic life is called for
